What is Cyclophosphamide used for and its side effects?
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Alkylating agent
Used for non-hodgkin's and burkitts lymphoma, or in combo with
methotrexate and fluorouracil for breast cancer. also used for RA
SE: alopecia (less thrombocytopenia), SIADH, N/V
,To treat trichomoniasis/bacterial vaginosis
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Metrondiazole + clindamycin cream
BBW for avastin (Bevaclizumab)
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GI perforation, hemorrhage, and wound healing problems
This drug is an Anthracycline antibiotic that intercalates DNA, is used for solid tumors
and leukemias in combination.
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doxorubicin
A vaccine strategy that uses an antigen that attracts a huge immune response, isolates
this gene, and adds it to a non pathogenic organism, which is then injected.
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Live recombinant vaccine
,Step-down from steroids > 2 weeks
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convert over 2 weeks to once a day dose while decreasing the second
dose and increasing the morning dose
This antibiotic is used for Gram + positive infections as IV only, and inhibits cell wall
formation as a B lactam antibiotic. What are the side effects?
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Vancomycin (IV only except in the case of C. diff)
(bactericidal
Gram positive ONLY- MRSA and c. diff.
G+ specific b/c it can't penetrate LPS layer(
Can cause "RED MAN SYNDROME" so give with slow infusion and pre-treat
with antihistimines
Nephrotoxic, Ototoxic, Thrombophlebitis
This vaccine can be either killed (requires boosters), or live-attenuated (which may
mutate) and infect unvaccinated populations.
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Polio
(note: contraindications: allergy, pregnancy, current illness)
, What are the 3 mechanisms for antibiotic resistance?
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Drug fails to reach target, is inactivated, or target is changed
Broad spectrum antifungal (systemic) that can cause Side effects involving GI, CNS,
rash, hepatotoxicity, significant drug interactions, N/V up to 10%, decrease
testosterone, gynecomastia, alopecia, menstrual irreg, at high doses decrease
cortisol synthesis.
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Ketoconazole
(CI: with antacids/cimetidine, fatal terfenadine/coumadin interaction)
This is an antimalarial drug used in combination with other drugs. Made from
wormwood shrub
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artemisinin
Treatment for Traveler's diarrhea
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Give this one a try later!
Alkylating agent
Used for non-hodgkin's and burkitts lymphoma, or in combo with
methotrexate and fluorouracil for breast cancer. also used for RA
SE: alopecia (less thrombocytopenia), SIADH, N/V
,To treat trichomoniasis/bacterial vaginosis
Give this one a try later!
Metrondiazole + clindamycin cream
BBW for avastin (Bevaclizumab)
Give this one a try later!
GI perforation, hemorrhage, and wound healing problems
This drug is an Anthracycline antibiotic that intercalates DNA, is used for solid tumors
and leukemias in combination.
Give this one a try later!
doxorubicin
A vaccine strategy that uses an antigen that attracts a huge immune response, isolates
this gene, and adds it to a non pathogenic organism, which is then injected.
Give this one a try later!
Live recombinant vaccine
,Step-down from steroids > 2 weeks
Give this one a try later!
convert over 2 weeks to once a day dose while decreasing the second
dose and increasing the morning dose
This antibiotic is used for Gram + positive infections as IV only, and inhibits cell wall
formation as a B lactam antibiotic. What are the side effects?
Give this one a try later!
Vancomycin (IV only except in the case of C. diff)
(bactericidal
Gram positive ONLY- MRSA and c. diff.
G+ specific b/c it can't penetrate LPS layer(
Can cause "RED MAN SYNDROME" so give with slow infusion and pre-treat
with antihistimines
Nephrotoxic, Ototoxic, Thrombophlebitis
This vaccine can be either killed (requires boosters), or live-attenuated (which may
mutate) and infect unvaccinated populations.
Give this one a try later!
Polio
(note: contraindications: allergy, pregnancy, current illness)
, What are the 3 mechanisms for antibiotic resistance?
Give this one a try later!
Drug fails to reach target, is inactivated, or target is changed
Broad spectrum antifungal (systemic) that can cause Side effects involving GI, CNS,
rash, hepatotoxicity, significant drug interactions, N/V up to 10%, decrease
testosterone, gynecomastia, alopecia, menstrual irreg, at high doses decrease
cortisol synthesis.
Give this one a try later!
Ketoconazole
(CI: with antacids/cimetidine, fatal terfenadine/coumadin interaction)
This is an antimalarial drug used in combination with other drugs. Made from
wormwood shrub
Give this one a try later!
artemisinin
Treatment for Traveler's diarrhea
Give this one a try later!
