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ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE EXAM-LATEST UPDATE | MOSTLY TESTED QUESTIONS AND ANSWERS-RATED 100% CORRECT!!ALREADY GRADED A+

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ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE EXAM-LATEST UPDATE | MOSTLY TESTED QUESTIONS AND ANSWERS-RATED 100% CORRECT!!ALREADY GRADED A+

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ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY
CERTIFICATE EXAM-LATEST UPDATE | MOSTLY TESTED
QUESTIONS AND ANSWERS-RATED 100% CORRECT!!
ALREADY GRADED A+
Lesson 1: Foundations to Set the Stage - CORRECT ANSWERS



Focusing on Cellular Structure and Function - CORRECT ANSWERS



The Normal Cell Cycle - CORRECT ANSWERS -The cell cycle refers to the ordered seres of
processes of DNA replication and mitosis, or cell division



-Cell nucleus regulates these processes by gathering and processing complexes molecular information



Interphase and Mitotic Phase - CORRECT ANSWERS Cell division produces two identical cells
through these two major phases



During interphase: - CORRECT ANSWERS Cell grows and DNA is replicated through the
following three steps:



1: First growth phase (G1 or first gap)



2: Synthesis phase (S phase)



3:Mitotic Phse (M phase)



First Growth Phase (G1 or first gap) - CORRECT ANSWERS -cells increase in size



-reproduce RNA



-"quality assurance" test that the cell will be ready to synthesis DNA

,ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY
CERTIFICATE EXAM-LATEST UPDATE | MOSTLY TESTED
QUESTIONS AND ANSWERS-RATED 100% CORRECT!!
ALREADY GRADED A+


-Length of time is variable, can be from hours to days



Synthesis Phase (S phase) - CORRECT ANSWERS -DNA replicates



-Results in the formation of identical pairs of DNA (chromatids)



-which are attached a t the centromere



-lasts 2-10 hours



Mitotic Phase (M phase) - CORRECT ANSWERS -Replicated chromosomes are aligned,
separated, and move into 2 new, identical daughter cells



-takes about 30-60 minutes



Major points of cell regulation are entry and exit from - CORRECT ANSWERS -G1 checkpoint



-S Phase



-G2 checkpoint



-M phase

,ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY
CERTIFICATE EXAM-LATEST UPDATE | MOSTLY TESTED
QUESTIONS AND ANSWERS-RATED 100% CORRECT!!
ALREADY GRADED A+
Restriction Point - CORRECT ANSWERS -The transition from the resting phase into an actively
dividing phase (G0-G1) is a point where cellular transformation can occur



-During this time, cells pass through a transition phase known as a restriction point



-Extracellular growth factors trigger reentry into G1, and GF are required to send the cells past the
restriction point, or the point of no return



G0 Phase (resting phase) - CORRECT ANSWERS -After mitosis, cells may enter back into the G1
phase or go into a resting phase, known as G0



-Most cells in the human body reside in G0



-Exceptions to this are those that are (Resting in G0 phase) - CORRECT ANSWERS -Exceptions to
this are those that are metabollically active, such as



-granulocytes



-and the epithelium of the GI tract



Cell Cycling Time - CORRECT ANSWERS Amount of time from mitosis to mitosis



Cell cycle video and image - CORRECT ANSWERS
http://highered.mheducation.com/sites/0072495855/student_view0/chapter2/
animation__how_the_cell_cycle_works.html

, ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY
CERTIFICATE EXAM-LATEST UPDATE | MOSTLY TESTED
QUESTIONS AND ANSWERS-RATED 100% CORRECT!!
ALREADY GRADED A+
Check points in the Cell Cycle: Keeping it All Under Control - CORRECT ANSWERS -The cell cycle
is carefully controlled through a series of checkpoints



-Variation in duplication or distribution of chromosomes during cell division can alter the genetic
information passed on to daughter cells, leading to cellular dysfunction and disease, such as cancer



-These checkpoints monitor for DNA integrity and control progression through mitosis



Progression through the cell cycle is controlled through two proteins: - CORRECT ANSWERS 1.
cyclines (D, E, A, B)



2. Cyclin-dependent kinases (CDKs)



-Cyclin-CDK complex allows the cell to progress through each phase of the cell cycle



Locations of proteins Cyclins (D, E, A, B) and CDKs - CORRECT ANSWERS -(G0-G1) : Cyclin D and
CDK 4/6



-Early S: Cyclin E and CDK 1/2



-Late S: Cyclin A and CDK 1/2



-G2: CDK 1/2 and cyclin A



-Before M: CDK 1 and Cyclin B
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