Clayton's Basic Pharmacology for Nurses: Chapter 2
questions with verified answers
3 routes of drug administration: Ans✓✓✓ - enteral
- parenteral
- percutaneous
a drug only forms a bond with a receptor if: Ans✓✓✓ - the drug and the receptor
have similar shapes
- the drug has a chemical affinity for the receptor
a patient with renal failure often has a ___________________ in the action and
duration of a drug if the dosage and frequency of administration are not adjusted
to allow for the patient's reduced renal function Ans✓✓✓ increase
absorption of a drug is slowest when administered this way Ans✓✓✓
subcutaneous injection
after administration, all drugs go through 5 stages: Ans✓✓✓ - liberation
- absorption
- distribution
- metabolism
- excretion
ampicillin + gentamicin = ampicillin inactivates gentamicin Ans✓✓✓
incompatibility
, an injury resulting from medical intervention related to a drug; medication errors
Ans✓✓✓ adverse drug events (ADE)
any noxious, unintended and undesired effect of a drug which occurs at dosages
used in humans for prophylaxis, diagnosis, or therapy Ans✓✓✓ adverse drug
reaction (ADR)
aspirin + codeine = much greater analgesic effect Ans✓✓✓ synergistic effect
classes of medication which account for the largest number of ADR's Ans✓✓✓ -
antibiotics
- cardiovascular medicines
- cancer chemotherapy agents
- analgesics
- antiinflammatory agents
common drugs that bind to enzymes and increase the metabolism of other drugs:
Ans✓✓✓ - phenobarbital
- carbamazepine
- rifampin
- phenytoin
drug interactions are elicited in two ways: Ans✓✓✓ - by agents that when
combined increase the actions of one or both drugs
- by agents that when combined decrease the effectiveness of one or both drugs
questions with verified answers
3 routes of drug administration: Ans✓✓✓ - enteral
- parenteral
- percutaneous
a drug only forms a bond with a receptor if: Ans✓✓✓ - the drug and the receptor
have similar shapes
- the drug has a chemical affinity for the receptor
a patient with renal failure often has a ___________________ in the action and
duration of a drug if the dosage and frequency of administration are not adjusted
to allow for the patient's reduced renal function Ans✓✓✓ increase
absorption of a drug is slowest when administered this way Ans✓✓✓
subcutaneous injection
after administration, all drugs go through 5 stages: Ans✓✓✓ - liberation
- absorption
- distribution
- metabolism
- excretion
ampicillin + gentamicin = ampicillin inactivates gentamicin Ans✓✓✓
incompatibility
, an injury resulting from medical intervention related to a drug; medication errors
Ans✓✓✓ adverse drug events (ADE)
any noxious, unintended and undesired effect of a drug which occurs at dosages
used in humans for prophylaxis, diagnosis, or therapy Ans✓✓✓ adverse drug
reaction (ADR)
aspirin + codeine = much greater analgesic effect Ans✓✓✓ synergistic effect
classes of medication which account for the largest number of ADR's Ans✓✓✓ -
antibiotics
- cardiovascular medicines
- cancer chemotherapy agents
- analgesics
- antiinflammatory agents
common drugs that bind to enzymes and increase the metabolism of other drugs:
Ans✓✓✓ - phenobarbital
- carbamazepine
- rifampin
- phenytoin
drug interactions are elicited in two ways: Ans✓✓✓ - by agents that when
combined increase the actions of one or both drugs
- by agents that when combined decrease the effectiveness of one or both drugs
