BASIC AND CLINICAL PHARMACOLOGY 15TH EDITIONK
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ATZUNG TREVOR TEST BANK
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INCLUSIVEpOFpCHAPTERSp1-66pCOMPLETEpWITHpEXPLAINEDpANSWERS
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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapterp1.pIntroduction:pThepNaturepofpDrugsp&pDrugpDevelopmentp&pRegulation
1.
Apnursepworkingpinpradiologypadministerspiodineptopappatientpwhopisphavingp
apcomputedptomographyp(CT)pscan.pThepnursepworkingponptheponcologypunitpa
dministerspchemotherapyptoppatientspwhophavepcancer.pAtpthepPublicpHealthpD
epartment,papnursepadministerspapmeasles-mumps-
rubellap(MMR)pvaccineptopap14-month-
oldpchildpaspaproutinepimmunization.pWhichpbranchpofppharmacologypbestpdesc
ribespthepactionspofpallpthreep nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacologypispthepstudypofpthepbiologicpeffectspofpchemicals.pNursesparepinv
olvedpwithpclinicalppharmacologyporppharmacotherapeutics,pwhichpispapbranchp
ofppharmacologypthatpdealspwithpthepusespofpdrugsptoptreat,pprevent,pandpdiagno
sepdisease.pThepradiologypnursepispadministeringpapdrugptophelppdiagnosepapdise
ase.pTheponcologypnursepispadministeringpapdrugptophelpptreatpapdisease.pPharma
coeconomicspincludespanypcostspinvolvedpinpdrugptherapy.
Pharmacodynamicspinvolvesphowpapdrugpaffectspthepbodypandppharmacokinetic
spisphowpthepbodypactsponpthepbody.
2.
WhenpinvolvedpinpphasepIIIpdrugpevaluationpstudies,pwh
atpresponsibilitiespwouldpthepnursephave?
A) Workingpwithpanimalspwhoparepgivenpexperimentalp drugs
B) Choosingpappropriateppatientsptopbepinvolvedpinpthepdrugp study
C) Monitoringpandpobservingppatientspcloselypforpadversep effects
D) Conductingpresearchptopdeterminepeffectivenesspofpthep drug
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Ans: C
Feedback:
PhasepIIIpstudiespinvolvepusepofpapdrugpinpapvastpclinicalppopulationpinpwhichpp
atientsparepaskedptoprecordpanypsymptomsptheypexperiencepwhileptakingpthepdr
ugs.pNursespmaypbepresponsiblepforphelpingpcollectpandpanalyzepthepinformati
onptopbepsharedpwithpthepFoodpandpDrugpAdministrationp(FDA)pbutpwouldpnotp
conductpresearchpindependentlypbecausepnursespdopnotpprescribepmedications
.pUsepofpanimalspinpdrugptestingpispdonepinptheppreclinicalptrials.pSelectppatient
spwhoparepinvolvedpinpphasepIIpstudiesptopparticipatepinpstudiespwhereptheppart
icipantsphavepthepdiseasepthepdrugpispintendedptoptreat.pTheseppatientsparepmon
itoredpcloselypforpdrugpactionpandpadversepeffects.pPhasepIpstudiespinvolvephe
althyphumanpvolunteerspwhoparepusuallyppaidpforptheirpparticipation.pNursesp
maypobservepforpadversepeffectspandptoxicity.
3.
Apphysicianphasporderedpintramuscularp(IM)pinjectionspofpmorphine,papnarco
tic,peveryp4phourspaspneededpforppainpinpapmotorpvehiclepaccidentpvictim.pThepn
ursepispawarepthispdrugphaspaphighpabuseppotential.pUnderpwhatpcategorypwouldp
morphinepbepclassified?
A) SchedulepI
B) SchedulepII
C) SchedulepIII
D) SchedulepIV
Ans: B
Feedback:
NarcoticspwithpaphighpabuseppotentialparepclassifiedpaspSchedulepIIpdrugspbec
ausepofpseverepdependencepliability.pSchedulepIpdrugsphavephighpabuseppotent
ialpandpnopacceptedpmedicalpuse.pSchedulepIIIpdrugsphavepaplesserpabuseppote
ntialpthanpIIpandpanpacceptedpmedicalpuse.pSchedulepIVpdrugsphaveplowpabusep
potentialpandplimitedpdependencep liability.
4.
Whatpconceptpispconsideredpwhenpgenericpdrugsparepsubstitutedpforpbran
dpnamepdrugs?
A) Bioavailability
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