how long does it take for side effects of a medication to wear off after it has been d/c? - Answers 1-2
weeks
what is pharmacokinetics? - Answers what the body does to the drug
what is the result of decreased total body water? - Answers decreased distribution of water soluble
drugs
what is the result of decreased plasma protein (albumin)? - Answers decreased distribution of highly
albumin bound drug
increases free drug, which causes therapeutic & adverse side effects
what is the result of decreased hepatic blood flow & size? - Answers decreased metabolism
what is the result of decreased renal plasma flow & mass? - Answers decreased elimination
what is the result of increased % of body fat? - Answers increased distribution of lipid soluble drugs
what is pharmacodynamics? - Answers what drugs do to the body
what is the result of decreased number & sensitivity of receptors? - Answers decreased agonist OR
increased antagonist
what is the result of decreased baroreceptor reflex & decreased sensitivity? - Answers decreased
homeostatic response
what are side effects of first generation antihistamines? - Answers confusion
dry mouth
constipation
what is the FDA class warning for antipsychotics? - Answers increased risk of CVA
when is it acceptable to use an anti-parkinsonian agent? - Answers acute dystonia with laryngeal spasm
when is it acceptable to use anti-psychotics? - Answers low dose antipsychotics for behavioral purposes
& chemo n/v
how long do long acting benzos act in the body of a normal adult? - Answers 100 hours = 4 days
how long do long acting benzos act in the body of an adult > 65 y/o? - Answers almost 150 hours
how is meperidine excreted? - Answers by the kidneys
, what are pts at an increased risk for when taking NSAIDs? - Answers GI bleed
what are pts at an increased risk for when taking muscle relaxants? - Answers fractures
what drugs may exacerbate a disease or syndrome? - Answers anticholinergics
antipsychotics
benzos
OTC drugs like cimetidine, ranitidine
if a pt presents with delirium, what is the first thing you should look at? - Answers if there have been any
changes in the pt's medications in the last 4 weeks
what medications may cause an increased fall risk in elderly pts? - Answers antiepileptics
antipsychotics
benzos
Z drugs
antidepressants
opioids
pharmacokinetic sis when one drug alters the concentration of another by altering its.... - Answers
absorption
distribution
metabolism
excretion
what is the MC pharmacokinetic problem? - Answers metabolism
how are most drugs metabolized? - Answers cytochrome P450
what are ways that drugs modulate the pharmacologic effect of another in pharmacodynamics? -
Answers additive
synergistic
antagonistic
what is the role of absorption in pharmacokinetics? - Answers GI motility
pH