NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
Chapter 18. Drugs Affecting the Endocrine System: Pancreatic Hormones and Antidiabetic
p p p p p p p p p p p
Drugs
• Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secr
p p p p p p p p p p p
etions. Each replacement drug has lipase, protease, and amylase components, but the dru
p p p p p p p p p p p p
g is prescribed in units of:
p p p p p
a. Lipase
b. Protease
c. Amylase
d. Pancreatin
• Brands of pancreatic enzyme replacement drugs are:
p p p p p p
a. Bioequivalent
b. About the same in cost per unit of lipase across brands
p p p p p p p p p p
c. Able to be interchanged between generic and brand-name products to reduce cost
p p p p p p p p p p p
d. None of the above p p p
• When given subcutaneously, how long until neutral protamine Hagedorn insulin begins to tak
p p p p p p p p p p p p
e effect (onsetof action) after administration?
p p p p p p
a. 15 to 30 minutes p p p
b. 60 to 90 minutes p p p
c. 3 to 4 hours p p p
d. 6 to 8 hours p p p
• Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and
p p p p p p p p p p p p p p p
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
symptoms ofhypoglycemia include: p p p
a. “Fruity” breath odor and rapid respiration p p p p p
b. Diarrhea, abdominal pain, weight loss, and hyper p p p p p p
tensionc. Dizziness, confusion, diaphoresis, and tac
p p p p p p
hycardia
d. Easy bruising, palpitations, cardiac dysrhythmias, and coma
p p p p p p p
• Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
p p p p p p p p p p p p
a. Increase blood glucose levels p p p
b. Produce unexplained diaphoresis p p
c. Interfere with the ability of the body to metabolize p p p p p p p p p
glucosed. Mask the signs and symptoms of altered gluc
p p p p p p p p p
ose levels p
• Lispro is an insulin analogue produced by recombinant DNA technology. W
p p p p p p p p p p
hich of thefollowing statements about this form of insulin is NOT true?
p p p p p p p p p p p p
a. Optimal time of preprandial injection is 15 minutes. p p p p p p p
b. Duration of action is increased when the dose is increased.
p p p p p p p p p
c. It is compatible with neutral protamine Hagedorn insulin.
p p p p p p p
d. It has no pronounced peak.
p p p p
• The decision may be made to switch from twice daily neutral protamine Haged
p p p p p p p p p p p p
orn (NPH)insulin to insulin glargine to improve glycemia control throughout t
p p p p p p p p p p p
he day. If this is done:
p p p p p
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
a. The initial dose of glargine is reduced by 20% to avoid hypoglycemia.
p p p p p p p p p p p
b. The initial dose of glargine is 2 to 10 units per day.
p p p p p p p p p p p
c. Patients who have been on high doses of NPH will need tests for insulin antibodies.
p p p p p p p p p p p p p p
d. Obese patients may require more than 100 units per day.
p p p p p p p p p
• When blood glucose levels are difficult to control in type 2 diabetes some form of i
p p p p p p p p p p p p p p p
nsulin maybe added to the treatment regimen to control blood glucose and limit co
p p p p p p p p p p p p p p
mplication risks. p
Which ofthe following statements is accurate based on research?
p p p p p p p p
a. Premixed insulin analogues are better at lowering HbA1C and have le
p p p p p p p p p p
ss risk forhypoglycemia.
p p p
b. Premixed insulin analogues and the newer premixed insulins are associated
p p p p p p p p p p
with moreweight gain than the oral antidiabetic agents.
p p p p p p p p
c. Newer premixed insulins are better at lowering HbA1C and postprandi
p p p p p p p p p
al glucoselevels than long-acting insulins.
p p p p p
d. Patients who are not controlled on oral agents and have postprandial hype
p p p p p p p p p p p
rglycemiacan have neutral protamine Hagedorn insulin added at bedtime.
p p p p p p p p p
• Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:
p p p p p p p p p p p p p p p
a. Substitutes for insulin usually secreted by the p p p p p p p p
ancreasb. Decreases glycogenolysis by the liver
p p p p p p
c. Increasespthepreleasepofpinsulinpfrompbetapcells
d. Decreasespperipheralpglucoseputilization
• Prior to prescribing metformin, the provider should:
p p p p p p
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
, NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022 p p
a. Draw a serum creatinine to assess renal function
p p p p p p p
b. Try the patient on insulin
p p p p
c. Tell the patient to increase iodine intake
p p p p p p
d. Have the patient stop taking any sulfonylurea to avoid dangerous drug interactions
p p p p p p p p p p p
• The action of “gliptins” is different from other antidiabetic agents because they:
p p p p p p p p p p p
a. Have a low risk for hypoglycemia
p p p p p
b. Are not associated with weight gain
p p p p p
c. Close ATP-dependent potassium channels in the beta cell
p p p p p p p
d. Act on the incretin system to indirectly increase insulin production
p p p p p p p p p
• Sitagliptin has been approved for:
p p p p
a. Monotherapy in once-daily doses p p p
b. Combination therapy with metformin p p p
c. Both 1 and 2
p p p p
d. Neither 1 nor 2 p p p
• GLP-1 agonists: p
a. Directly bind to a receptor in the pancreatic beta cell
p p p p p p p p p
b. Have been approved for monotherapy
p p p p
c. Speed gastric emptying to decrease appetite
p p p p p
d. Can be given orally once daily
p p p p p
• Avoid concurrent administration of exenatide with which of the following drugs?
p p p p p p p p p p
a. Digoxin
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022 p p
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
Chapter 18. Drugs Affecting the Endocrine System: Pancreatic Hormones and Antidiabetic
p p p p p p p p p p p
Drugs
• Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secr
p p p p p p p p p p p
etions. Each replacement drug has lipase, protease, and amylase components, but the dru
p p p p p p p p p p p p
g is prescribed in units of:
p p p p p
a. Lipase
b. Protease
c. Amylase
d. Pancreatin
• Brands of pancreatic enzyme replacement drugs are:
p p p p p p
a. Bioequivalent
b. About the same in cost per unit of lipase across brands
p p p p p p p p p p
c. Able to be interchanged between generic and brand-name products to reduce cost
p p p p p p p p p p p
d. None of the above p p p
• When given subcutaneously, how long until neutral protamine Hagedorn insulin begins to tak
p p p p p p p p p p p p
e effect (onsetof action) after administration?
p p p p p p
a. 15 to 30 minutes p p p
b. 60 to 90 minutes p p p
c. 3 to 4 hours p p p
d. 6 to 8 hours p p p
• Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and
p p p p p p p p p p p p p p p
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
symptoms ofhypoglycemia include: p p p
a. “Fruity” breath odor and rapid respiration p p p p p
b. Diarrhea, abdominal pain, weight loss, and hyper p p p p p p
tensionc. Dizziness, confusion, diaphoresis, and tac
p p p p p p
hycardia
d. Easy bruising, palpitations, cardiac dysrhythmias, and coma
p p p p p p p
• Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
p p p p p p p p p p p p
a. Increase blood glucose levels p p p
b. Produce unexplained diaphoresis p p
c. Interfere with the ability of the body to metabolize p p p p p p p p p
glucosed. Mask the signs and symptoms of altered gluc
p p p p p p p p p
ose levels p
• Lispro is an insulin analogue produced by recombinant DNA technology. W
p p p p p p p p p p
hich of thefollowing statements about this form of insulin is NOT true?
p p p p p p p p p p p p
a. Optimal time of preprandial injection is 15 minutes. p p p p p p p
b. Duration of action is increased when the dose is increased.
p p p p p p p p p
c. It is compatible with neutral protamine Hagedorn insulin.
p p p p p p p
d. It has no pronounced peak.
p p p p
• The decision may be made to switch from twice daily neutral protamine Haged
p p p p p p p p p p p p
orn (NPH)insulin to insulin glargine to improve glycemia control throughout t
p p p p p p p p p p p
he day. If this is done:
p p p p p
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
a. The initial dose of glargine is reduced by 20% to avoid hypoglycemia.
p p p p p p p p p p p
b. The initial dose of glargine is 2 to 10 units per day.
p p p p p p p p p p p
c. Patients who have been on high doses of NPH will need tests for insulin antibodies.
p p p p p p p p p p p p p p
d. Obese patients may require more than 100 units per day.
p p p p p p p p p
• When blood glucose levels are difficult to control in type 2 diabetes some form of i
p p p p p p p p p p p p p p p
nsulin maybe added to the treatment regimen to control blood glucose and limit co
p p p p p p p p p p p p p p
mplication risks. p
Which ofthe following statements is accurate based on research?
p p p p p p p p
a. Premixed insulin analogues are better at lowering HbA1C and have le
p p p p p p p p p p
ss risk forhypoglycemia.
p p p
b. Premixed insulin analogues and the newer premixed insulins are associated
p p p p p p p p p p
with moreweight gain than the oral antidiabetic agents.
p p p p p p p p
c. Newer premixed insulins are better at lowering HbA1C and postprandi
p p p p p p p p p
al glucoselevels than long-acting insulins.
p p p p p
d. Patients who are not controlled on oral agents and have postprandial hype
p p p p p p p p p p p
rglycemiacan have neutral protamine Hagedorn insulin added at bedtime.
p p p p p p p p p
• Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:
p p p p p p p p p p p p p p p
a. Substitutes for insulin usually secreted by the p p p p p p p p
ancreasb. Decreases glycogenolysis by the liver
p p p p p p
c. Increasespthepreleasepofpinsulinpfrompbetapcells
d. Decreasespperipheralpglucoseputilization
• Prior to prescribing metformin, the provider should:
p p p p p p
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022
p p
, NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022 p p
a. Draw a serum creatinine to assess renal function
p p p p p p p
b. Try the patient on insulin
p p p p
c. Tell the patient to increase iodine intake
p p p p p p
d. Have the patient stop taking any sulfonylurea to avoid dangerous drug interactions
p p p p p p p p p p p
• The action of “gliptins” is different from other antidiabetic agents because they:
p p p p p p p p p p p
a. Have a low risk for hypoglycemia
p p p p p
b. Are not associated with weight gain
p p p p p
c. Close ATP-dependent potassium channels in the beta cell
p p p p p p p
d. Act on the incretin system to indirectly increase insulin production
p p p p p p p p p
• Sitagliptin has been approved for:
p p p p
a. Monotherapy in once-daily doses p p p
b. Combination therapy with metformin p p p
c. Both 1 and 2
p p p p
d. Neither 1 nor 2 p p p
• GLP-1 agonists: p
a. Directly bind to a receptor in the pancreatic beta cell
p p p p p p p p p
b. Have been approved for monotherapy
p p p p
c. Speed gastric emptying to decrease appetite
p p p p p
d. Can be given orally once daily
p p p p p
• Avoid concurrent administration of exenatide with which of the following drugs?
p p p p p p p p p p
a. Digoxin
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
p p p p p p
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
p p p p p p p p
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
p p p p p p p p
T UPDATE 2022 p p
