Test Bank for Pharmacotherapeutics for Advanced Practice, 5th Edition by Virginia Poole Arcangelo, 9781975160593, Covering Chapters 1-56 | Includes Rationales

Pharmacotherapeutics for advanced practice a practical
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approach 5th edition test bank
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Pharmacology for Nurses (Mercy College)
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,Chapter 1 Issues for the Practitioner in Drug Therapy
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MULTIPLE CHOICE k




1. Nurse practitioner prescriptive authority is regulated by:
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A. The National Council of State Boards of Nursing
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B. The U.S. Drug Enforcement Administration
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C. The State Board of Nursing for each state
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D. The State Board of Pharmacy
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ANS: C k PTS: k k 1

2. Physician Assistant (PA) prescriptive authority is regulated by:
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A. The National Council of State Boards of Nursing
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B. The U.S. Drug Enforcement Administration
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C. The State Board of Nursing
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D. The State Board of Medical Examiners
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ANS: D k PTS: k k 1

3. Clinical judgment in prescribing includes:
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A. Factoring in the cost to the patient of the medication prescribed
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B. Always prescribing the newest medication available for the disease process
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C. Handing out drug samples to poor patients
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D. Prescribing all generic medications to cut costs k k k k k k




ANS: A k PTS: k k 1

4. Criteria for choosing an effective drug for a disorder include:
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A. Asking the patient what drug they think would work best for them
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B. Consulting nationally recognized guidelines for disease management
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C. Prescribing medications that are available as samples before writing a prescription
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D. Following U.S. Drug Enforcement Administration (DEA) guidelines for
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k prescribing
ANS: B k PTS: k k 1

5. Nurse practitioner practice may thrive under health-care reform due to:
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A. The demonstrated ability of nurse practitioners to control costs and improve patient
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k outcomes
B. The fact that nurse practitioners will be able to practice independently
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C. The fact that nurse practitioners will have full reimbursement under health-care
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reform
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D. The ability to shift accountability for Medicaid to the state level
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ANS: A k PTS: k k 1

,Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
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MULTIPLE CHOICE k




1. A patient’s nutritional intake and lab work reflects hypoalbuminemia. This is critical to
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prescribing because:
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A. Distribution of drugs to target tissue may be affected k k k k k k k k


B. The solubility of the drug will not match the site of absorption
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C. There will be less free drug available to generate an effect
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D. Drugs bound to albumin are readily excreted by the kidney
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ANS: A k PTS: k k 1

2. Drugs that have a significant first-pass effect:
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A. Must be given by the enteral (oral) route only
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B. Bypass the hepatic circulation k k k


C. Are rapidly metabolized by the liver and may have little if any desired action
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D. Are converted by the liver to more active and fat-soluble forms
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ANS: C k PTS: k k 1

3. The route of excretion of a volatile drug will likely be:
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A. The kidneys k


B. The lungs k


C. The bile and feces k k k


D. The skin k




ANS: B k PTS: k k 1

4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of the k k k k k k k k k k k k


k drug. Storage reservoirs:
k k


A. Assure that the drug will reach its intended target tissue
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B. Are the reason for giving loading doses
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C. Increase the length of time a drug is available and active
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D. Are most common in collagen tissues
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ANS: C k PTS: k k 1

5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s:
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A. Propensity to go to the target receptor k k k k k k


B. Biological half-life k


C. Pharmacodynamics
D. Safety and side effects k k k




ANS: B k PTS: k k 1

6. Azithromycin dosing requires the first day’s dose be twice those of the other 4 days of the
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prescription. This is considered a loading dose. A loading dose:
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A. Rapidly achieves drug levels in the therapeutic range
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B. Requires four to five half-lives to attain k k k k k k


C. Is influenced by renal function
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, D. Is directly related to the drug circulating to the target tissues
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ANS: A k PTS: k k 1

7. The point in time on the drug concentration curve that indicates the first sign of a therapeutic
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k effect is the:
k k


A. Minimum adverse effect level k k k


B. Peak of action k k


C. Onset of action k k


D. Therapeutic range k




ANS: C k PTS: k k 1

8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
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A. When the drug has a wide therapeutic range
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B. When the drug will be administered for a short time only
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C. When there is a high correlation between the dose and saturation of receptor sites
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D. To determine if a drug is in the therapeutic range
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ANS: D k PTS: k k 1

9. A laboratory result indicates the peak level for a drug is above the minimum toxic
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concentration. This means that the:
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A. Concentration will produce therapeutic effects k k k k


B. Concentration will produce an adverse response k k k k k


C. Time between doses must be shortened
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D. Duration of action of the drug is too long k k k k k k k k




ANS: B k PTS: k k 1

10. Drugs that are receptor agonists may demonstrate what property?
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A. Irreversible binding to the drug receptor site k k k k k k


B. Up-regulation with chronic use k k k


C. Desensitization or down-regulation with continuous use k k k k k


D. Inverse relationship between drug concentration and drug action
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ANS: C k PTS: k k 1

11. Drugs that are receptor antagonists, such as beta blockers, may cause:
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A. Down-regulation of the drug receptor k k k k


B. An exaggerated response if abruptly discontinued
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C. Partial blockade of the effects of agonist drugs
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D. An exaggerated response to competitive drug agonists
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ANS: B k PTS: k k 1

12. Factors that affect gastric drug absorption include:
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A. Liver enzyme activity k k


B. Protein-binding properties of the drug molecule k k k k k


C. Lipid solubility of the drug k k k k


D. Ability to chew and swallow k k k k




ANS: C k PTS: k k 1