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NU 578 / NU578 UNIT 1 EXAM. DRUGS. QUESTIONS WITH 100% CORRECT ANSWERS.

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The nurse is preparing to administer a dose of clonidine [Catapres]. Which is the best description of the action of this drug? A. It selectively activates alpha2 receptors in the central nervous system (CNS) adrenergic blocker, clonidine's action occurs in the CNS. B. It causes peripheral activation of alpha1 and alpha2 receptors. C. It depletes sympathetic neurons of norepinephrine. D. It directly blocks alpha and beta receptors in the periphery -Clonidine is an alpha2-adrenergic agonist that causes selective activation of alpha2 receptors in the CNS. This in turn reduces sympathetic outflow to the blood vessels and the heart. Although the body's responses are similar to those from a peripheral adrenergic blocker, clonidine's action occurs in the CNS. The nurse is assessing a patient in a clinic who has been taking clonidine [Catapres] for hypertension. Which clinical findings are most indicative of an adverse effect of this drug? A. Cough and wheezing B. Epigastric pain and diarrhea C. Drowsiness and dry mouth D. Positive Combs’ test result and anemia -Drowsiness and dry mouth are common adverse effects (35% to 40%) associated with clonidine. The other effects are not commonly associated with clonidine. The nurse is caring for a patient prescribed methyldopa [Aldomet]. Which laboratory test is most important to obtain before treatment? A. Creatinine level B. Serum glucose level C. White blood cell count D. Hematocrit -Methyldopa causes a positive Coombs' test result in about 10% to 20% of patients. About 5% of those patients develop hemolytic anemia. A Coombs' test and blood cell count (hematocrit, hemoglobin, or red cell count) should be done prior to treatment to establish a baseline and periodically thereafter Which statement is most appropriate for the nurse to include in the discharge teaching plan for a 30-year-old woman beginning a new prescription of clonidine [Catapres]? A. "If you stop taking this drug abruptly, your blood pressure might go up very high.". B. "You will need to have your blood drawn regularly to check for anemia." C. "Take this medication first thing in the morning to reduce nighttime wakefulness." D. "This medication often is used to manage hypertension during pregnancy." -Rebound hypertension is a potential adverse effect of clonidine. Patients should be warned against abrupt withdrawal. Clonidine is not associated with anemia. It can cause drowsiness and usually is taken at night. Clonidine is not recommended for pregnant patients. Following the administration of guanfacine [Tenex], the nurse should assess for which effects? A. Constipation and tachycardia B. Sweating and vivid dreams C. Skin rash and headache D. Sedation and dry mouth -The major adverse effects of guanfacine [Tenex] are sedation and dry mouth. The nurse is preparing to administer medication to the following patients. Which medication should the nurse question before administering? A. Clonidine [Duraclon] to a patient with severe pain B. Guanfacine [Intuniv] to a patient with attention-deficit/hyperactivity disorder (ADHD) C. Reserpine to a patient with a history of depression D. Methyldopa [Aldomet] to a patient with a diagnosis of hypertension -The reserpine's side effect of greatest concern is severe depression, and it is contraindicated in patients with a history of depressive disorders. The nurse is evaluating the teaching done with a patient who has a new prescription for transdermal clonidine [Catapres-TTS]. Which statement by the patient indicates understanding of the nurse's teaching? A. "I will apply the patch to a hairless, intact skin area on my upper arm." B. "I need to apply the patch before my evening meal." C. "The patch will not cause any skin reaction." D. "I will need to apply a new patch once every 3 to 4 days." -For a transdermal clonidine patch the patient is instructed to apply the patch to hairless, intact skin on the upper arm or torso, and to apply a new patch every 7 days. Localized skin reactions are common with transdermal clonidine patches. A patient who abuses cocaine, opioids, and other drugs frequently abuses which drug? A. Guanfacine B. Reserpine C. Methyldopa D. Clonidine -Patients who abuse cocaine, opioids, and other drugs frequently abuse clonidine as well. '

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2024/2025
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NU 578 UNIT 1 EXAM
A nurse is preparing to give an oral dose of drug X to treat a patient's high blood
pressure. After giving the drug, the nurse finds that it not only reduces the blood
pressure without serious harmful effects, but it also causes the patient to have
nausea and headache. Based on this information, which property of an ideal drug is
this drug lacking?
A. Effectiveness
B. Safety
C. Selectivity
D. Ease of administration


-The drug is effective in lowering the blood pressure and safe in that it does not cause
harmful effects. However, as do most drugs, it causes other effects besides the one
response desired; therefore, it lacks selectivity. The oral form provides ease of
administration.




The nurse is preparing to give a drug with certain properties. Which property of the
drug is the most compelling indication that it should not be given?
A. The drug produces an unwanted side effect.
B. The drug is difficult to administer.
C. The drug's effects are reversible.
D. The drug is not effective for its intended purpose.

,-If a drug is not effective, there is no justification for giving it. Some drugs may be
given even though they produce unwanted side effects or are difficult to administer.
Reversible action is a desired property for most drugs.




Why is it important for drugs to have ease of administration?
A. Fewer administration errors
B. Less risk of side effects
C. Greater chemical stability
D. Greater likelihood of reversibility
-Ease of administration increases convenience and adherence and can reduce
administration errors. Ease of administration is not related to side effects, chemical
stability, or reversibility.




The nurse teaches a patient not to consume alcohol with nitroglycerine, because the
blood pressure often drops significantly when nitroglycerine is taken with alcohol.
Which drug property does this illustrate?
A. Chemical instability
B. Drug interaction
C. Reversible action
D. Drug selectivity
-When two or more drugs are taken together, they can interact, causing either
increased or decreased drug responses. In this case, alcohol would increase the
nitroglycerine response. Chemical instability, reversible action, and drug selectivity
are not related to this situation.

,When studying the impact a drug has on the body, the nurse is reviewing what?
A. The drug's pharmacokinetics
B. The drug's selectivity
C. The drug's pharmacodynamics
D. The drug's predictability.
-Pharmacodynamics can be thought of as the impact of drugs on the body.
Pharmacokinetics describes the movement of drugs through the body. Selectivity is
the ability of a drug to elicit only the response for which it is given. Predictability is
the degree of certainty about how a patient will respond to a certain drug.




When studying the effects of drugs in humans, the nurse is learning about what?
A. Pharmacology
B. Clinical pharmacology
C. Therapeutics
D. Effectiveness
-Clinical pharmacology is the study of the effects of drugs in humans. Pharmacology
can be defined as the study of drugs and their interactions with living systems.
Therapeutics, also known as pharmacotherapeutics, is the use of drugs to diagnose,
prevent, or treat disease or to prevent pregnancy. The term effectiveness indicates
that the drug elicits the intended response or responses.

, Which statement by a new nurse indicates that further study is indicated?
A. Effectiveness is the most important property a drug can have.
B. There is no such thing as a safe drug.
C. Drugs are defined as illegal substances.
D. There is no such thing as a selective drug; all medications cause side effects.
-A drug is any chemical that can affect living processes. All the other statements are
correct.




What is the ultimate concern for the nurse when administering a drug?
A. Intensity of the response
B. Dosage
C. Route of administration
D. Timing of administration
-The ultimate concern for the nurse when administering a drug is the intensity of the
response, which is determined by the dosage size, route of administration, and
timing of administration.




What is the objective of drug therapy?
A. To provide maximum benefit with minimal harm
B. To provide minimum benefit with maximum harm
C. To provide total relief of symptoms regardless of harm
D. To provide as much benefit as possible

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