NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, ren
Study online at https://quizlet.com/_dcrufh
blood cell formation
Hematopoiesis Fetus- liver and spleen
Adult- bone marrow
A condition in which the blood is deficient
Anemia in red blood cells, in hemoglobin, or in
total volume.
formation of red blood cells
Erythropoiesis
In kidney in response to hypoxia
Large RBC's, normal hemoglobin
macrocytic normochromic anemia
Folic acid or Vitamin B12 deficiency
small, abnormally shaped erythrocytes
that are not able to carry normal hemo-
microcytic hypochromic anemia
globin
Thalassemia- mediterranean
Characterized by red cells that are rela-
tively normal in size and normal hemo-
normocytic normochromic anemia globin
Aplastic, hemorrhagic, hemolytic, sickle
cell
anemia resulting when there is not
enough iron to build hemoglobin for red
iron deficiency anemia blood cells
Affects children, poverty, child bearing
age
red blood cells
Most abundant cell in the body
Erythrocytes
Responsible for tissue oxygenation
Mitotic division- 100-120 days
A genetic disorder in which erythroctyes
sickle cell anemia take on an abnormal curved or "sickle"
shape (Hb-s)
Inherited defect in the ability to produce
Thalassemia hemoglobin, usually seen in persons of
Mediterranean background.
, NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, ren
Study online at https://quizlet.com/_dcrufh
Lack of mature erythrocytes caused by
pernicious anemia inability to absorb vitamin B12 into the
bloodstream
Characterized by an inadequate number
of circulating red blood cells due to the
premature destruction of red blood cells
hemolytic anemia
by the spleen
Pancytopenia- reduction in all 3 types of
blood cells (RBC, WBC, Plt)
Hormone secreted by the kidney to stim-
ulate the production of red blood cells by
Erythropoietin (EPO) bone marrow
In response to hypoxia
In the fetus the liver produces this
Iron-containing protein in red blood cells
that carries oxygen for delivery to cells
Hemoglobin
4 molecules of O2
Made of polypeptide, heme, iron
Iron def anemia is major cause after this
Removal of stomach often leads to
marked decrease in production of gastric
anemia due to gastrectomy
acid. This acid is necessary to convert
dietary iron to a form that is more readily
absorbed by the duodenum
Sickle cell disease, ABO or Rh incompat-
hemolytic anemia causes
ibility, drug induced
Innate:
1. Phagocytosis
PRR or opsonization w/ complement
2. Secrete Cytokines: Recruit more cells,
inflammation, fever, etc.
Adaptive:
1. Phagocytosis: opsonization with com-
plement or Abs
2. Secrete cytokines: recruit more cells
Study online at https://quizlet.com/_dcrufh
blood cell formation
Hematopoiesis Fetus- liver and spleen
Adult- bone marrow
A condition in which the blood is deficient
Anemia in red blood cells, in hemoglobin, or in
total volume.
formation of red blood cells
Erythropoiesis
In kidney in response to hypoxia
Large RBC's, normal hemoglobin
macrocytic normochromic anemia
Folic acid or Vitamin B12 deficiency
small, abnormally shaped erythrocytes
that are not able to carry normal hemo-
microcytic hypochromic anemia
globin
Thalassemia- mediterranean
Characterized by red cells that are rela-
tively normal in size and normal hemo-
normocytic normochromic anemia globin
Aplastic, hemorrhagic, hemolytic, sickle
cell
anemia resulting when there is not
enough iron to build hemoglobin for red
iron deficiency anemia blood cells
Affects children, poverty, child bearing
age
red blood cells
Most abundant cell in the body
Erythrocytes
Responsible for tissue oxygenation
Mitotic division- 100-120 days
A genetic disorder in which erythroctyes
sickle cell anemia take on an abnormal curved or "sickle"
shape (Hb-s)
Inherited defect in the ability to produce
Thalassemia hemoglobin, usually seen in persons of
Mediterranean background.
, NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, ren
Study online at https://quizlet.com/_dcrufh
Lack of mature erythrocytes caused by
pernicious anemia inability to absorb vitamin B12 into the
bloodstream
Characterized by an inadequate number
of circulating red blood cells due to the
premature destruction of red blood cells
hemolytic anemia
by the spleen
Pancytopenia- reduction in all 3 types of
blood cells (RBC, WBC, Plt)
Hormone secreted by the kidney to stim-
ulate the production of red blood cells by
Erythropoietin (EPO) bone marrow
In response to hypoxia
In the fetus the liver produces this
Iron-containing protein in red blood cells
that carries oxygen for delivery to cells
Hemoglobin
4 molecules of O2
Made of polypeptide, heme, iron
Iron def anemia is major cause after this
Removal of stomach often leads to
marked decrease in production of gastric
anemia due to gastrectomy
acid. This acid is necessary to convert
dietary iron to a form that is more readily
absorbed by the duodenum
Sickle cell disease, ABO or Rh incompat-
hemolytic anemia causes
ibility, drug induced
Innate:
1. Phagocytosis
PRR or opsonization w/ complement
2. Secrete Cytokines: Recruit more cells,
inflammation, fever, etc.
Adaptive:
1. Phagocytosis: opsonization with com-
plement or Abs
2. Secrete cytokines: recruit more cells
