Neoplasia NUR 631 UPDATED ACTUAL
Exam Questions and CORRECT Answers
Cancer is associated with? - CORRECT ANSWER - Altered expression of cellular genes
that are responsible for proliferation and differentiation
What characteristics of benign tumors can make them potentially lethal? - CORRECT
ANSWER - 1. Proximity to critical structures (obstructing airway, growth in brain creating
increased intracranial pressure)
2. Some benign cells have shown potential to become malignant
Describe the common characteristics of benign tumors - CORRECT ANSWER - 1. Do not
invade adjacent tissue
2. typically encapsulated
3. Resemble their tissue of origin (liver, skin)
_____ is a lack of differentiated features in malignant cells.
What is this correlated with? - CORRECT ANSWER - Anaplasia
More aggressive tumors
What characteristic determines the diagnosis of malignancy? - CORRECT ANSWER -
Invasion of local tissue or metastasis to distant sites
The growth rate of _____ tumors is typically slow whereas the growth rate of ____tumors is
rapid - CORRECT ANSWER - Benign
Malignant
, ____tumors rarely have areas of necrosis and tend to maintain structure similar to their cells of
origin.
______ tumors often have areas of necrosis and have abnormal shape and size - CORRECT
ANSWER - Benign
Malignant
The great majority of human cancers (90%) are carcinomas from malignant transformation of? -
CORRECT ANSWER - Epithelial cells
List some abnormal behaviors of cancer cells that allow them to proliferate? - CORRECT
ANSWER - 1. Cancer cells proliferate despite lack of growth-initiating signals from the
environment
2. Cancer cells escape apoptotic signals
3. Cancer cells are genetically unstable and evolve by accumulating new mutations at a much
faster rate than normal cells
4. Cancer cells develop proangiogenic signaling abilities allowing them to create their own
vascular supply
5. Cancer cells develop the ability to evade immune surveillance and destruction
Americans have an almost ______ lifetime risk of developing cancer - CORRECT
ANSWER - One in Three
What are some modifiable risk factors that can influence cancer risk? - CORRECT
ANSWER - Tobacco and Alcohol use, obesity, Nutrition, Sun exposure
What exposure increases the risk of cancers in the anogenital, head and neck, and liver? -
CORRECT ANSWER - Certain viruses increase the risk of cancer in these areas
What form of cancer accounts for the highest estimated deaths in both males and females? -
CORRECT ANSWER - Lung & Bronchus
Exam Questions and CORRECT Answers
Cancer is associated with? - CORRECT ANSWER - Altered expression of cellular genes
that are responsible for proliferation and differentiation
What characteristics of benign tumors can make them potentially lethal? - CORRECT
ANSWER - 1. Proximity to critical structures (obstructing airway, growth in brain creating
increased intracranial pressure)
2. Some benign cells have shown potential to become malignant
Describe the common characteristics of benign tumors - CORRECT ANSWER - 1. Do not
invade adjacent tissue
2. typically encapsulated
3. Resemble their tissue of origin (liver, skin)
_____ is a lack of differentiated features in malignant cells.
What is this correlated with? - CORRECT ANSWER - Anaplasia
More aggressive tumors
What characteristic determines the diagnosis of malignancy? - CORRECT ANSWER -
Invasion of local tissue or metastasis to distant sites
The growth rate of _____ tumors is typically slow whereas the growth rate of ____tumors is
rapid - CORRECT ANSWER - Benign
Malignant
, ____tumors rarely have areas of necrosis and tend to maintain structure similar to their cells of
origin.
______ tumors often have areas of necrosis and have abnormal shape and size - CORRECT
ANSWER - Benign
Malignant
The great majority of human cancers (90%) are carcinomas from malignant transformation of? -
CORRECT ANSWER - Epithelial cells
List some abnormal behaviors of cancer cells that allow them to proliferate? - CORRECT
ANSWER - 1. Cancer cells proliferate despite lack of growth-initiating signals from the
environment
2. Cancer cells escape apoptotic signals
3. Cancer cells are genetically unstable and evolve by accumulating new mutations at a much
faster rate than normal cells
4. Cancer cells develop proangiogenic signaling abilities allowing them to create their own
vascular supply
5. Cancer cells develop the ability to evade immune surveillance and destruction
Americans have an almost ______ lifetime risk of developing cancer - CORRECT
ANSWER - One in Three
What are some modifiable risk factors that can influence cancer risk? - CORRECT
ANSWER - Tobacco and Alcohol use, obesity, Nutrition, Sun exposure
What exposure increases the risk of cancers in the anogenital, head and neck, and liver? -
CORRECT ANSWER - Certain viruses increase the risk of cancer in these areas
What form of cancer accounts for the highest estimated deaths in both males and females? -
CORRECT ANSWER - Lung & Bronchus
