Test Bank for Basic and Clinical Pharmacology 14th Edition By Bertram G. Katzung Chapter 1-66 Complete Guide A+

Pagea1aofa822




BASIC AND CLINICAL PHARMACOLOGY 14thE
a

a a
a

a
a

Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
a a a a
a

a a
a




DITION KATZUNG TREVOR Test Bank
a a a a




Chaptera1.aIntroduction:aTheaNatureaofaDrugsa&aDrugaDevelopmenta&aRegulation


1.
Aanurseaworkingainaradiologyaadministersaiodineatoaaapatientawhoaisahavingaa
acomputedatomographya(CT)ascan.aTheanurseaworkingaonatheaoncologyaunitaad


ministersachemotherapyatoapatientsawhoahaveacancer.aAtatheaPublicaHealthaDep
artment,aaanurseaadministersaaameasles-mumps-rubellaa(MMR)avaccineatoaaa14-
month-
oldachildaasaaaroutineaimmunization.aWhichabranchaofapharmacologyabestadescr
ibesatheaactionsaofaallathreea nurses?
A) Pharmacoeconomics

B) Pharmacotherapeutics

C) Pharmacodynamics

D) Pharmacokinetics

Ans: B

Feedback:

Pharmacologyaisatheastudyaofatheabiologicaeffectsaofachemicals.aNursesaareainvo
lvedawithaclinicalapharmacologyaorapharmacotherapeutics,awhichaisaaabranchaof
apharmacologyathatadealsawithatheausesaofadrugsatoatreat,aprevent,aandadiagnosea


disease.aThearadiologyanurseaisaadministeringaaadrugatoahelpadiagnoseaaadisease
.aTheaoncologyanurseaisaadministeringaaadrugatoahelpatreataaadisease.aPharmacoe
conomicsaincludesaanyacostsainvolvedainadruga therapy.
Pharmacodynamicsainvolvesahowaaadrugaaffectsatheabodyaandap
harmacokineticsaisahowatheabodyaactsaonatheabody.


2.
Aaphysicianahasaorderedaintramusculara(IM)ainjectionsaofamorphine,aaanarco
tic,aeverya4ahoursaasaneededaforapainainaaamotoravehicleaaccidentavictim.aTheanu
rseaisaawareathisadrugahasaaahighaabuseapotential.aUnderawhatacategoryawouldam
orphineabeaclassified?
A) ScheduleaI


WWW.THENURSINGMASTERY.COM
WWW.NURSYLAB.COM

, Pagea2aofa822



B) ScheduleaII




WWW.THENURSINGMASTERY.COM
WWW.NURSYLAB.COM

, Pagea3aofa822




C) ScheduleaIII

D) ScheduleaIV

Ans: B

Feedback:

NarcoticsawithaaahighaabuseapotentialaareaclassifiedaasaScheduleaIIadrugsabecau
seaofasevereadependencealiability.aScheduleaIadrugsahaveahighaabuseapotentiala
andanoaacceptedamedicalause.aScheduleaIIIadrugsahaveaaalesseraabuseapotentiala
thanaIIaandaanaacceptedamedicalause.aScheduleaIVadrugsahavealowaabuseapotent
ialaandalimitedadependencea liability.


3.
WhenainvolvedainaphaseaIIIadrugaevaluationastudies,awhataresponsibilitie
sawouldatheanurseahave?
A) Workingawithaanimalsawhoaareagivenaexperimentala drugs

B) Choosingaappropriateapatientsatoabeainvolvedainatheadruga study

C) Monitoringaandaobservingapatientsacloselyaforaadversea effects

D) Conductingaresearchatoadetermineaeffectivenessaofathea drug

Ans: C

Feedback:

PhaseaIIIastudiesainvolveauseaofaaadrugainaaavastaclinicalapopulationainawhichap
atientsaareaaskedatoarecordaanyasymptomsatheyaexperienceawhileatakingatheadr
ugs.aNursesamayabearesponsibleaforahelpingacollectaandaanalyzeatheainformati
onatoabeasharedawithatheaFoodaandaDrugaAdministrationa(FDA)abutawouldanota
conductaresearchaindependentlyabecauseanursesadoanotaprescribeamedications
.aUseaofaanimalsainadrugatestingaisadoneainatheapreclinicalatrials.aSelectapatients
awhoaareainvolvedainaphaseaIIastudiesatoaparticipateainastudiesawhereatheapartic


ipantsahaveatheadiseaseatheadrugaisaintendedatoatreat.aTheseapatientsaareamonit
oredacloselyaforadrugaactionaandaadverseaeffects.aPhaseaIastudiesainvolveahealt
hyahumanavolunteersawhoaareausuallyapaidaforatheiraparticipation.aNursesamay
aobserveaforaadverseaeffectsaandatoxicity.




4.
Whataconceptaisaconsideredawhenagenericadrugsaareasubstitutedaforabran
danameadrugs?
A) Bioavailability

WWW.THENURSINGMASTERY.COM
WWW.NURSYLAB.COM

, Pagea4aofa822




B) Criticalaconcentration

C) Distribution

D) Half-life

Ans: A

Feedback:

Bioavailabilityaisatheaportionaofaaadoseaofaaadrugathatareachesatheasystemicacirc
ulationaandaisaavailableatoaactaonabodyacells.aBindersausedainaaagenericadrugama
yanotabeatheasameaasathoseausedainatheabrandanameadrug.aTherefore,atheawayath
eabodyabreaksadownaandausesatheadrugamayadiffer,awhichamayaeliminateaaagen
ericadrugasubstitution.aCriticalaconcentrationaisatheaamountaofaaadrugathataisanee
dedatoacauseaaatherapeuticaeffectaandashouldanotadifferabetweenagenericaandabr
andanameamedications.aDistributionaisatheaphaseaofapharmacokinetics,awhichai
nvolvesatheamovementaofaaadrugatoatheabodysatissuesaandaisatheasameainageneri
caandabrandanameadrugs.aAadrugsahalf-
lifeaisatheatimeaitatakesaforatheaamountaofadrugatoadecreaseatoahalfatheapeakalevel,
awhichashouldanotachangeawhenasubstitutingaaagenerica medication.




5.
Aanurseaisaassessingatheapatientsahomeamedicationause.aAfteralisteningatoath
eapatientalistacurrentamedications,atheanurseaasksawhataprioritya question?
A) Doayouatakeaanyagenerica medications?

B) Areaanyaofatheseamedicationsaorphana drugs?

C) Areatheseamedicationsasafeatoatakeaduringa pregnancy?

D) Doayouatakeaanyaover-the-countera medications?

Ans: D

Feedback:

Itaisaimportantaforatheanurseatoaspecificallyaquestionauseaofaover-the-
counteramedicationsabecauseapatientsamayanotaconsiderathemaimportant.aTheap
atientaisaunlikelyatoaknowatheameaningaofaorphanadrugsaunlessatheyatooaareahea
lthacareaproviders.aSafetyaduringapregnancy,auseaofaaagenericamedication,aoracl
assificationaofaorphanadrugsaareathingsatheapatientawouldabeaunableatoaanswera
butacouldabeafoundainareferenceabooksaifatheanurseawishesatoaresearchathem.




WWW.THENURSINGMASTERY.COM
WWW.NURSYLAB.COM