Judy Harrison is a 38-year-old African American female with a long history of diabetes mellitus type 2 and
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hypertension. She has experienced renal insufficiency for the last two years. Her current medications include t t t t t t t t t t t t t t t
an angiotensin converting enzyme inhibitor (ACEI), a diuretic, and an oral hypoglycemic agent. She reports to
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the nurse at the clinic that she has lost her appetite and is very fatigued. She adds that she has to get up to go to
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the bathroom several times during the night and has trouble catching her breath at times. Her current weight is
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114 lbs (51.7 kg). She is scheduled for diagnostic studies to evaluate for the onset of end-stage renal disease
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(ESRD). - correct answer Background for Chronic Kidney Disease HESI Case Study
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Which explanation by the nurse is an accurate description of CKD?
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-There are frequent exacerbations since half of all nephrons are damaged
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-It is a fatal disorder unless renal replacement therapy is received.
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-The condition has a rapid onset with frequent remissions
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-symptoms are reversible with lifelong medication - correct answer It is a fatal disorder unless renal
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replacement therapy is received. t t t
CKD is fatal unless some form of renal replacement therapy dialysis or organ transplant is done whereas acute
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renal failure has a good prognosis for the return of kidney function if appropriate supportive care is provided
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during the acute. t t
-symptoms are reversible with lifelong medication = chronic kidney disease is progressive irreversible kidney
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injury acute renal failure may be reversible with adequate supportive care during the acute episode
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-The condition has a rapid onset with frequent remissions = acute renal failure has a rapid onset but chronic
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kidney disease has a gradual onset occurring over months or years neither form of renal failure has frequent
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periods of remission t t
,-There are frequent exacerbations since half of all nephrons are damaged =
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half of all nephrons are often damaged in acute renal failure in CKD about 90% of nephrons are typically
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involved
What additional information in Judy's history may be related to the onset of ESRD?
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A) Hypertension
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B) Polycystic Kidney Disease
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C) Hysterectomy at age 35
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D) Female gender
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E) African-American ethnicity
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F) Hypertension - correct answer E + F
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African American ethnicity = African American clients are more likely to develop ESKD and have hypertensive
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ESKD
Hypertension
Polycystic Kidney Disease = Polycystic kidney disease gene mutation will develop kidney cysts by age 30 half of
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these people develop CKD by age 50t t t t t t
-hysterectomy at age 35 = t t t t t
this is not a risk factor for CKD
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-Female gender = CKD does not seem to be more common in either gender
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-HTN = hypertension is one of the primary causes of CKD the vast majority of clients with CKD have
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hypertension which may be either the cause or the result of CKD t t t t t t t t t t t
Which lab value is likely to be decreased in a client with chronic kidney disease?
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-Serum K+ t
,-Serum BUN and Creatinine t t t
-Serum Ca+ t
-Serum Phosphorous - correct answer Serum calcium = Serum calcium is decreased in CKD in response to an
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increase in serum phosphorus t t t
-serum potassium levels are increased in CKD as the kidney loses the ability to remove potassium from the
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body clients with CKD should be assessed carefully for symptoms of hyperkalemia
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- serum creatinine and BUN are tests which evaluate the removal of nitrogenous wastes by the kidney. Both
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are increased in CKD although BUN levels are directly impacted by protein intake hydration status and other
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factors
- serum phosphorus is increased as less phosphorus is excreted by the kidney
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Judy's hemoglobin level is 7.8. Which underlying pathology does the nurse recognize as the cause of this
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abnormal lab value? t t
-Fewer red blood cells are being formed
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-hematuria results in blood loss t t t t
-renal waste products destroy red blood cells
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-dehydration causes dilutional anemia - correct answer Fewer red blood cells are being formed = hemoglobin
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is decreased as the kidneys become less able to produce erythropoietin necessary for the formation of red
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blood cells t
-hematuria results in blood loss = CKD does not result in hematuria t t t t t t t t t t t
-renal waste products destroy red blood cells = this does not occur in CKD
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-dehydration causes dilutional anemia = if dehydration occurred it would be likely to result in a high
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hemoglobin level rather than a low level t t t t t t
What is the correct interpretation of these ABGs?
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Metabolic acidosis (compensated) t t
respiratory alkalosis (compensated) t t
metabolic alkalosis (compensated) t t
, respiratory acidosis (compensated) - correct answer Metabolic acidosis (compensated) = an excessive
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bicarbonate is excreted, the HCO3 level decreases causing metabolic acidosis (decreased pH). compensation
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occurs when an increased rate and depth of respirations reduce the CO2 levels returning the pH to low normal
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- alkalosis would be indicated by an increased pH rather than decreased pH
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-respiratory acidosis (compensated) = this is a compensated acidosis but if it were respiratory in nature the
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CO2, would be elevated rather than decreased
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Which additional assessment finding is consistent with ESRD?
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A) Clay colored stool
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b) tall tented T waves on c) electrocardiogram
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d) decrease attention span
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e) stridor t
f) yellow Gray pallor - correct answer B, D, F
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Tall tented T waves on electrocardiogram = potassium excretion occurs mainly through the kidney. any
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increase in potassium load during the later stages of CKD can lead to hyperkalemia (high serum potassium
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levels)
Decreased attention span = problems ranging from lethargy to seizures or coma which may indicate uremic
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encephalopathy
Yellow-gray pallor = the client with ESRD often exhibits a yellow Gray pallor as the result of anemia and uremia.
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in addition the client with ESRD may exhibit other skin manifestations such as bruising and uremic frost (a very
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late manifestation) t
- Stridor is a crowing respiratory noise due to bronchoconstriction it is not an expected finding in ESRD
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- Clay-colored stools = not a manifestation seen in ESRD
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Which explanation best describes the pathology resulting in her hypertension?
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