RNA processing I
Friday, November 08, 2024 10:06 AM
BIOL200%2
0lecture%...
The steps are coordinated with the transcription (happen at the same time)
BIOL200 Page 1
, Pausing phase = when the cap is added
Degradation mecanisms target mrnas that arent capped
Mrna has to go to the cytoplasm – this helps it go there
BIOL200 Page 2
, 7 heptomers repeated with a lot of serine (cuz they can get phosphorylated)
We have 52 repeats
Ser 5 is the first to get phosphorylated
Ser2 in elongation = phosphorylated
BIOL200 Page 3
, At the paused state – the 5 prime end is close to the CTD = capping
Both events take place in the nucleus
COME BACK HERE FOR LECTURE TO SEE WHAT HE SAID ABOUT 2
CTD could be considered as a scaffold on which many proteins can bind
BIOL200 Page 4
Friday, November 08, 2024 10:06 AM
BIOL200%2
0lecture%...
The steps are coordinated with the transcription (happen at the same time)
BIOL200 Page 1
, Pausing phase = when the cap is added
Degradation mecanisms target mrnas that arent capped
Mrna has to go to the cytoplasm – this helps it go there
BIOL200 Page 2
, 7 heptomers repeated with a lot of serine (cuz they can get phosphorylated)
We have 52 repeats
Ser 5 is the first to get phosphorylated
Ser2 in elongation = phosphorylated
BIOL200 Page 3
, At the paused state – the 5 prime end is close to the CTD = capping
Both events take place in the nucleus
COME BACK HERE FOR LECTURE TO SEE WHAT HE SAID ABOUT 2
CTD could be considered as a scaffold on which many proteins can bind
BIOL200 Page 4
