Test bank for evolutionary analysis 5th edition by herron jon freeman scott isbn 9780321998378.

TEST BANK FOR
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EvolutionaryeAnalysise5theEditionebyeHerroneJon;eFreemaneScotteISBNe9780321998378eChapt
ere1-20

Chaptere1e e AeCaseeforeEvolutionaryeThinking:eUnderstandingeHIV

1) InewhicheofetheefollowingeregionsehaseAIDSekilledetheelargestenumbereofeindividuals?
A) India
B) Sub-SaharaneAfrica
C) UnitedeStates
D) China
E) UnitedeKingdom
eAnswer:e Be Section

:e 1.1
Skill:e Knowledge/Comprehension

2) TheeHIVevirusecontainsealleofetheefollowingecomponentseexcepte .
A) integrase
B) double-strandedeRNA
C) single-strandedeRNA
D) reverseetranscriptase
E) proteasee
Answer:eBeS
ection:e 1.1
Skill:e Knowledge/Comprehension

3) TheeacronymeHIVestandseforewhicheofetheefollowing?
A) humaneintercellularevirus
B) humaneimmuneevirus
C) humaneimmunodeficiencyevirus
D) humaneimmunityevirus
E) humaneimmunodeficiencyevectore
Answer:e C
Section:e 1.1
Skill:e Knowledge/Comprehension

4) WhicheofetheefollowingeenzymeseiseresponsibleeforetranscribingeviraleRNAeintoeDNA?
A) RNAepolymerase
B) reverseetranscriptase
C) DNAepolymerase
D) reverseeintegrase
E) RNAeduplicase
eAnswer:e BeSectio

n:e 1.1
Skill:e Knowledge/Comprehension

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,5) TheeproteinsethateenableetheeHIVevirusetoebindetoecellseareetypicallyeCD4eandeCCR5.eOnewhatety
peeofecellseareetheseeproteinsetypicallyeobserved?
A) plasmaecells
B) dendriticecells
C) effectorehelpereTecells
D) memoryehelpereTecells
E) botheCeandeDe
Answer:e EeSecti
on:e 1.1
Skill:e Knowledge/Comprehension

6) TheeAIDSephaseeofeHIVeinfectionebeginsewhenetheeconcentrationeofeCD4eTecellseinetheebloodedr
opsebelowewhateconcentration?
A) 2,000ecellseperecubicemillimeter
B) 1,000ecellseperecubicemillimeter
C) 500ecellseperecubicemillimeter
D) 200ecellseperecubicemillimeter
E) NoeCD4eTecellseareeobserved.e
Answer:e D
Section:e 1.1
Skill:e Knowledge/Comprehension

7) WhicheofetheefollowingedrugecategorieseareeusedetoetreateHIVeinfections?
A) integraseeinhibitors
B) proteaseeinhibitors
C) reverseetranscriptaseeinhibitors
D) DNAseeinhibitors
E) fusioneinhibitors
eAnswer:e DeSectio

n:e 1.2
Skill:e Knowledge/Comprehension

8) CoreceptoreinhibitorseblockeHIVeinfectionebyepreventingewhicheofetheefollowing?
A) bindingeofetheeHIVevirioneontoetheeplasmaemembrane
B) bindingeofetheeHIVevirioneontoetheeCCR5ereceptor
C) bindingeofetheeHIVevirioneontoetheegp120eprotein
D) degradingetheecoreceptoresoetheevirionecannoteattach
E) bindingeofetheeHIVevirioneontoetheeCD4ereceptore
Answer:e B
Section:e 1.2
Skill:e Application/Analysis

9) Whateisetheeeffecteofethee∆32ealleleeofeCCR5eoneHIVebinding?
A) appearseonetheesurfaceeofeCD4eTecells,ebutetheeHIVevirioneiseunableetoeinfectetheehostecell
B) doesenoteappeareonetheesurfaceeofeCD4eTecells
C) appearseonetheesurfaceeofetheeCD4eTecellseandeinactivatesetheevirioneuponebinding
D) interferesewithebindingeofetheevirionetoetheeCD4ereceptoreprotein
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,E) appearseonetheesurfaceeofetheeCD4eTecellseandecausesetheevirionetoelyseeuponebindingeA
nswer:e B
Section:e 1.3
Skill:e Application/Analysis

10) Thee∆32ealleleeofeCCR5eisefoundeatetheehighestefrequencyeinewhicheofetheefollowingep
opulations?
A) Africans
B) Japanese
C) NortheAmericans
D) Europeans
E) SoutheAmericans
eAnswer:e De Sectio

n:e 1.3
Skill:e Knowledge/Comprehension

11) HIV-
1eisebelievedetoehaveebeenetransmittedetoehumansefromewhicheofetheefollowingeorganisms?
A) gorillas
B) sootyemangabeys
C) Africanegreenemonkeys
D) chimpanzees
E) baboonse
Answer:eDeS
ection:e 1.4
Skill:e Knowledge/Comprehension

12) HIV-1eGroupeMeiseresponsibleefore95%eofehumaneinfections.eWheneiseiteestimatedethateHIV-
1eGroupeMewasetransferredetoehumans?
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer:e Ce
Section:e 1.4
Skill:e Knowledge/Comprehension

13) AntibodieseandekillereTecellserecognizeeHIVeoreHIV-
infectedecellsebyebindingetoeshortepieceseofeviraleproteinsedisplayedeonetheeviruseoretheeinfectedehost
ecell.eTheseeshortepieceseofeviraleproteinseareecallede .

A) coateproteins
B) virosomes
C) proteosomes
D) epitopes
E) episomes
eAnswer:e D



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, Section:e 1.5
Skill:e Knowledge/Comprehension

14) Tetherineiseaneimportanteproteineproducedebyetheehost.eWhateisetheefunctioneofetetherineinepr
otectingeaehostecellefromeHIV?
A) tiesematuringevirionsetoetheemembraneeofetheehostecell,etherebyepreventingetheereleaseeofetheem
atureevirus
B) bindsetheevirusetoetheeexternalehostecellemembrane,etherebyepreventingetheevirusefromeenteringeth
eehostecell
C) bindsetheeviraleRNAetoereverseetranscriptase,ethusepreventingesynthesiseofetheeviraleDNA
D) bindsetheetwoeviraleRNAestrandsetogether,ethusepreventingetheetranscriptioneofeviraleDNAeineth
eehostecell
E) causesetheematuringevirionsetoeaggregateetogether,ethusepreventingetheirereleaseefrometheehostec
ell
Answer:e Ae
Section:e 1.5
Skill:e Application/Analysis

15) EarlyeinetheeinfectionewitheHIV,emostevirionsebindetoetheehostecelleusingeCCR5easeaeco
receptor.eAsetheeinfectioneprogresses,etheeHIVepopulationeevolvesetoeuseeanealternateecore
ceptor.eWhateisetheealternateecoreceptoretheseeX4eviruseseutilize?
A) Tetherin
B) CCR5α
C) vpu
D) TRIM5α
E) CXCR4
Answer:e Ee
Section:e 1.5
Skill:e Knowledge/Comprehension

16) InewhateregioneofetheeworldeisetheeincidenceeofeinfectionewitheHIVehighest?eA
nswer:e Sub-SaharaneAfrica
Section:e 1.1
Skill:e Knowledge/Comprehension

17) Originally,eHIVewasethoughtetoebeerestrictedetoetransmissioneduringehomosexualecontacteb
etweenegayemen.eListeotherewayseinewhicheHIVeisecurrentlyeknownetoebeetransmitted.
Answer:e HIVecanebeetransmittedebyeheterosexualesex,eoralesex,eneedleesharing,etransfusionewithecont
aminatedebloodeproducts,eothereunsafeemedicaleprocedures,echildbirtheandebreast-feeding.
Section:e 1.1
Skill:e Knowledge/Comprehension

18) WhatedoesetheeacronymeAIDSestandefor?eAnsw
er:e AcquiredeImmuneeDeficiencyeSyndromeeSectio
n:e 1.1
Skill:e Knowledge/Comprehension


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