©BRIGHTSTARS EXAM SOLUTIONS
11/16/2024 10:16 AM
NSG203 Unit 9 Study Guide Questions With
Correct Answers
What are the adverse effects of sulfonamides? - answer✔- allergic reaction is typically a
delayed cutaneous reaction (fever, rash)
- photosensitivity: can result in severe sunburn
- other: GI upset (N/V, diarrhea, pancreatitis, hepatotoxicity), hematologic (anemia,
thrombocytopenia)
what is beta-lactam antibiotics? - answer✔- penicillins
- inhibit enzymes that can inactivate penicillin antibiotics
- combination products of penicillins and beta-lactamase inhibitors (ampicillin/sulbactam-
unasyn)
- effective against gram-positive
- little if ant ability against gram-negative with the exception of extended-spectrum
(pipercillin/tazobactam-zosyn)
what is amoxicillin and ampicillin? - answer✔- beta-lactam antibiotics penicillins
- amoxicillin: used to treat infections in the ears, nose, throat, GU, skin and skin structures; can
be given with or without food and its available in PO form
- ampicillin: am[icillin anhydrous and ampicillin trihydrate given PO, ampicillin sodium is given
parenterally, and combination of ampicillin and sulbactam (unasyn) is most commonly used
what are the interactions to penicillin? - answer✔- methotrexate: increase methotrexate levels
- NSAIDs: increase the amount of free and active penicillin
- oral contraceptives: decreased efficacy of contraceptive
- warfarin: enhanced anticoagulant effect
1|Page
, ©BRIGHTSTARS EXAM SOLUTIONS
11/16/2024 10:16 AM
what is nursing care related to administration of antiinfectives? - answer✔- non-HIV antivirals:
use appropriate technique when administering (wear gloves when applying ointments to
prevent spread of disease)
- administer oral meds with meals to help minimize GI upset
- take medication for the entire course of therapy (if a dose is missed, take as soon as possible)
- IV acyclovir is stable for 12 hours at room temp but will precipitate if refrigerated (infuse over
at least an hr to prevent renal damage, increase fluids to help protect kidneys, monitor IV site
closely, doc. characteristics of lesions, implement appropriate isolation for chickenpox or
herpes zoster)
- HIV antivirals (antiretrovirals): follow any admin. and handling guidelines, film-coated oral
dosage forms (do not alter the drug), evenly space doses around the clock to maintain blood
levels, and administer with food unless contraindicated (indinacir)
what are the interactions to gentamicin? - answer✔- concurrent use of other nephrotoxic drugs
- concurrent use of loop diuretics increases the r/f ototoxicity
- warfarin: can potentiate warfarin activity
what is client education for quinolones? - answer✔- take for the full course of treatment
- do not administer with antacids, iron, zinc, multivitamins, or sucralfate
- educate about photosensitivity
what is the nurse care of a client on vancomycin? - answer✔- blood levels must be monitored
bc its nephrotoxic and ototoxic
- labs: liver function, kidney function, urinalysis, EKG, culture and sensitivity, CBC, assess for
superinfection
- assess trough levels: generally done before the 4th dose
- assess for "red man syndrome": flushing of the face, head, neck, and trunk associated with an
infucision rate that is too rapid
- assess BP as hypotension can develop with a rapid infusion
- there are many IV incompatibilities
- do not infuse any faster than 60 mins
- monitor IV site closely d/t extravasation
2|Page
11/16/2024 10:16 AM
NSG203 Unit 9 Study Guide Questions With
Correct Answers
What are the adverse effects of sulfonamides? - answer✔- allergic reaction is typically a
delayed cutaneous reaction (fever, rash)
- photosensitivity: can result in severe sunburn
- other: GI upset (N/V, diarrhea, pancreatitis, hepatotoxicity), hematologic (anemia,
thrombocytopenia)
what is beta-lactam antibiotics? - answer✔- penicillins
- inhibit enzymes that can inactivate penicillin antibiotics
- combination products of penicillins and beta-lactamase inhibitors (ampicillin/sulbactam-
unasyn)
- effective against gram-positive
- little if ant ability against gram-negative with the exception of extended-spectrum
(pipercillin/tazobactam-zosyn)
what is amoxicillin and ampicillin? - answer✔- beta-lactam antibiotics penicillins
- amoxicillin: used to treat infections in the ears, nose, throat, GU, skin and skin structures; can
be given with or without food and its available in PO form
- ampicillin: am[icillin anhydrous and ampicillin trihydrate given PO, ampicillin sodium is given
parenterally, and combination of ampicillin and sulbactam (unasyn) is most commonly used
what are the interactions to penicillin? - answer✔- methotrexate: increase methotrexate levels
- NSAIDs: increase the amount of free and active penicillin
- oral contraceptives: decreased efficacy of contraceptive
- warfarin: enhanced anticoagulant effect
1|Page
, ©BRIGHTSTARS EXAM SOLUTIONS
11/16/2024 10:16 AM
what is nursing care related to administration of antiinfectives? - answer✔- non-HIV antivirals:
use appropriate technique when administering (wear gloves when applying ointments to
prevent spread of disease)
- administer oral meds with meals to help minimize GI upset
- take medication for the entire course of therapy (if a dose is missed, take as soon as possible)
- IV acyclovir is stable for 12 hours at room temp but will precipitate if refrigerated (infuse over
at least an hr to prevent renal damage, increase fluids to help protect kidneys, monitor IV site
closely, doc. characteristics of lesions, implement appropriate isolation for chickenpox or
herpes zoster)
- HIV antivirals (antiretrovirals): follow any admin. and handling guidelines, film-coated oral
dosage forms (do not alter the drug), evenly space doses around the clock to maintain blood
levels, and administer with food unless contraindicated (indinacir)
what are the interactions to gentamicin? - answer✔- concurrent use of other nephrotoxic drugs
- concurrent use of loop diuretics increases the r/f ototoxicity
- warfarin: can potentiate warfarin activity
what is client education for quinolones? - answer✔- take for the full course of treatment
- do not administer with antacids, iron, zinc, multivitamins, or sucralfate
- educate about photosensitivity
what is the nurse care of a client on vancomycin? - answer✔- blood levels must be monitored
bc its nephrotoxic and ototoxic
- labs: liver function, kidney function, urinalysis, EKG, culture and sensitivity, CBC, assess for
superinfection
- assess trough levels: generally done before the 4th dose
- assess for "red man syndrome": flushing of the face, head, neck, and trunk associated with an
infucision rate that is too rapid
- assess BP as hypotension can develop with a rapid infusion
- there are many IV incompatibilities
- do not infuse any faster than 60 mins
- monitor IV site closely d/t extravasation
2|Page
