Ada Alvarez
STUDENT NAME _____________________________________
celecoxib ( Celebrex)
MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________
Analgesic, Anti-inflammatory, Antirrheumatic
CATEGORY CLASS ______________________________________________________________________
PURPOSE OF MEDICATION
Expected Pharmacological Action Therapeutic Use
Inhibits activity of cyclooxygenase-2 (COX-2) To relieve signs and symptoms of
osteoarthritis, rheumatoid arthritis, juvenile
this enzyme helps in prostaglandin rheumatoid arthritis, ankylosing spondylitis, to
production due to the inflammatory response. manage acute pain.
Complications Medication Administration
Dyspepsia, abdominal pain, heartburn, and nausea. Capsules 100mg-200mg twice
Impaired Kidney Function: Decreased urine output, weight daily, up to 400mg daily
gain from fluid retention, increased BUN, and creatinine
level. Increased risk of heart attack and stroke:with non
Contraindications/Precautions
Allergies to sulfonamide derivatives, aspirin and other
NSAIDs or history of apsirin-induced nasal polyps with
bronchospasm; hypersensitivity to celecoxib or its Nursing Interventions
components; treatment of pain after coronary artery
bypass graft surgery. History of smoking, drinking or poor general Assess range of motion, history
health status. History of ulcer disease or GI Bleeding of MI or heart failure, GI bleed,
hypertension, sulfonamide
allergy.
Assess patient for skin rash
frequently during therapy.
Interactions Monitor CBC, WBC, H&H, Liver
ACE inhibitors, angiotensin II receptor antagonists, beta monitor Urine output
blockers; Decreased antihypertensive effect of these monitor wt
drugs, increased risk of renal failure aspirin and other
salicylates, corticosteroids: Increased risk of GI ulceration
and other GI complications.
Client Education
Take with food, milk, or an
8oz glass of water to reduce
Evaluation of Medication Effectiveness gastric discomfort. Do not chew
or crush enteric-coated.
Reduction in inflammation, reduced fever, relief from mild Take exactly as directed. Advice prt to
to moderate pain, absence of injury. Reduce Join painin notify PCP promply if signd of GI
patients with osteoarthritis. Reduction in join tenderness, toxicity(abdominal pain) or allergies
reactions.
join swelling with reumatoid arthritis and juvenile
rheumatoid arthritis.
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