NR565 Advanced Pharmacology Midterm
Exam ACTUAL Exam Questions and
CORRECT Answers
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with greater risk for
those with diabetes and a risk score >7.5% - CORRECT ANSWER✔✔- ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a statin or
fibrate - CORRECT ANSWER✔✔- Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing absorption from
the small intestine, without affecting triglycerides - CORRECT ANSWER✔✔- Ezetimibe
Non-drug measures to lower LDL, including diet, exercise, weight control, and smoking
cessation - CORRECT ANSWER✔✔- Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally well-
tolerated side effects - CORRECT ANSWER✔✔- Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels, reduction of
preload and afterload, and promotion of vasodilation - CORRECT ANSWER✔✔- Organic
Nitrates Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes, including
grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal drugs, and
some CCB - CORRECT ANSWER✔✔- Ranolazine Contraindications
Avoid in children under 10 - CORRECT ANSWER✔✔- Statin Prescription Age
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply - CORRECT
ANSWER✔✔- CCB Role in Variant Angina
, Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help with
symptoms - CORRECT ANSWER✔✔- HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing cardiac
oxygen demand - CORRECT ANSWER✔✔- CCB Stable Angina
Prescribe a BB to help with increased heart rate - CORRECT ANSWER✔✔- Nitro Patches
Side Effect Response
When not used correctly, they lead to increased side effects, adverse reactions, and toxicity -
CORRECT ANSWER✔✔- CYP450 Inhibitors and Reducers
In patients with infrequent flareups (less than three per year), NSAIDs are the first line agent
for relieving pain - CORRECT ANSWER✔✔- Gouty Arthritis Treatment Decision
Prescribe a glucocorticoid (prednisone) or make dietary changes - CORRECT ANSWER✔✔-
Gouty Arthritis NSAID Ineffectiveness
Considered for long term treatment if a person has three or more gouty attacks per year -
CORRECT ANSWER✔✔- Colchicine Long Term Treatment
Should not be taken with statins or CYP3A4 inhibitors - CORRECT ANSWER✔✔-
Colchicine Contraindications
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis - CORRECT
ANSWER✔✔- Colchicine Adverse Effects
Can lead to severe cutaneous adverse reaction (SCAR) with symptoms like rash, fever,
eosinophilia, and liver and kidney function issues - CORRECT ANSWER✔✔- Allopurinol
Long Term Effect
Should be co-administered with NSAIDs or colchicine - CORRECT ANSWER✔✔-
Febuxostat Co-Administration
Exam ACTUAL Exam Questions and
CORRECT Answers
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with greater risk for
those with diabetes and a risk score >7.5% - CORRECT ANSWER✔✔- ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a statin or
fibrate - CORRECT ANSWER✔✔- Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing absorption from
the small intestine, without affecting triglycerides - CORRECT ANSWER✔✔- Ezetimibe
Non-drug measures to lower LDL, including diet, exercise, weight control, and smoking
cessation - CORRECT ANSWER✔✔- Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally well-
tolerated side effects - CORRECT ANSWER✔✔- Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels, reduction of
preload and afterload, and promotion of vasodilation - CORRECT ANSWER✔✔- Organic
Nitrates Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes, including
grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal drugs, and
some CCB - CORRECT ANSWER✔✔- Ranolazine Contraindications
Avoid in children under 10 - CORRECT ANSWER✔✔- Statin Prescription Age
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply - CORRECT
ANSWER✔✔- CCB Role in Variant Angina
, Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help with
symptoms - CORRECT ANSWER✔✔- HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing cardiac
oxygen demand - CORRECT ANSWER✔✔- CCB Stable Angina
Prescribe a BB to help with increased heart rate - CORRECT ANSWER✔✔- Nitro Patches
Side Effect Response
When not used correctly, they lead to increased side effects, adverse reactions, and toxicity -
CORRECT ANSWER✔✔- CYP450 Inhibitors and Reducers
In patients with infrequent flareups (less than three per year), NSAIDs are the first line agent
for relieving pain - CORRECT ANSWER✔✔- Gouty Arthritis Treatment Decision
Prescribe a glucocorticoid (prednisone) or make dietary changes - CORRECT ANSWER✔✔-
Gouty Arthritis NSAID Ineffectiveness
Considered for long term treatment if a person has three or more gouty attacks per year -
CORRECT ANSWER✔✔- Colchicine Long Term Treatment
Should not be taken with statins or CYP3A4 inhibitors - CORRECT ANSWER✔✔-
Colchicine Contraindications
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis - CORRECT
ANSWER✔✔- Colchicine Adverse Effects
Can lead to severe cutaneous adverse reaction (SCAR) with symptoms like rash, fever,
eosinophilia, and liver and kidney function issues - CORRECT ANSWER✔✔- Allopurinol
Long Term Effect
Should be co-administered with NSAIDs or colchicine - CORRECT ANSWER✔✔-
Febuxostat Co-Administration
