ABSITE Questions
2 weeks after a whipple operation, your affected person continues to have early satiety with
oral intake. You determine to start metoglopramide (Reglan) and erythromycin. What
receptor does erythromycin bind to growth gastrointestinal motility? - ANSMotilin (discovered
generally inside the belly, duodenum, and colon)
Proteins are synthesized from:
a. MRNA
b. TRNA
c. DsDNA
d. SsDNA - ANSmRNA
1 week after an APR, our affected person develops urosepsis requiring extent resuscitation,
antibiotics, and moderate quantities of levophed and vasopressin. E. Coli grows out from the
blood cultures. What part of the lipopolysaccharide complicated accounts for its toxicity -
ANSLipid A (with gram negative sepsis; stimulator of TNFα)
Steroid hormones:
a. Bind a receptor at the plasma membrane and spark off a plasma membrane enzyme
b. Bind a cytoplasmic receptor, input the nucleus, and affect transcription of proteins
c. Bind a receptor in the nucleus and have an effect on transcription of proteins
d. Do no longer enter the mobile - ANS(b)
Bind a receptor within the cellular cytoplasm, input the nucleus as a steroid-receptor
complex, and affect transcription of proteins
4 days after an Ivor-Lewis esophagectomy, you decide to begin enteral tube feeding thru a
J-tube. The long chain fatty acids contained inside the tube feeds:
a. Enter the movement thru the portal gadget
b. Enter the flow through lymphatics
c. Are only synthesized in the frame
d. Are now not found in chylomicrons - ANS(b)
Long-chain FAs input the body thru terminal lacteals (absorption via the lymphatic gadget)
both as unfastened LCFAs or as chylomicrons
Medium- and quick-chain FAs at the side of proteins/CHO input thru the portal flow
Cells divide in the course of what segment of the cell cycle?
,A. G1
b. S
c. G2
d. M - ANS(d)
Cells divide all through the M segment (most radiosensitive)
Cell cycle period is determined through what section of the cell cycle?
A. G1
b. S
c. G2
d. M - ANS(a)
G1 ↔ G0 phase determines cell cycle period (most variable cellular length)
Most RNA/protein synthesis
Of the subsequent, that is the maximum crucial thing inside the neovascularization of tumor
metastases?
A. HER receptor
b. VEGF receptor
c. Neu receptor
d. FGF receptor - ANS(d)
Vascular endothelial increase component (VEGF) receptor
For its anticoagulation results, heparin binds:
a. Protein C
b. Protein S
c. Anti-thrombin III
d. Factor VII - ANS(c)
ATIII (heparin-ATIII complicated binds thrombin, factor IX, element X, and component XI)
7 days after a kidney transplant, your affected person develops intense acute rejection with
vasculitis on biopsy. You determine to start the monoclonal antibody OKT3. Monoclonal
antibodies:
a. Bind 1 epitope at one web page
b. Bind 1 epitope at multiple sites
c. Bind a couple of epitopes on a single antigen
d. Bind multiple epitopes on a couple of antigens - ANS(a)
They bind one epitope at the precise identical binding web site
, You start coumadin on a affected person with a pulmonary embolus. Three days later, he
begins sloughing off skin across his legs and arms. All of the subsequent are authentic of
this sufferers most possibly situation except:
a. This probable might had been avoided by way of beginning heparin earlier than coumadin
b. Patients with protein C deficiency are greater liable to this hassle
c. The skin sloughing is resulting from pores and skin necrosis
d. This is probable due to hemophilia A - ANS(d)
Coumadin-brought on pores and skin necrosis takes place in patients started on coumadin
without being given heparin first. It consequences from a noticeably hypercoagulable
kingdom that could arise in some individuals due to the shorter half-life of protein C & S
compared to factors II, VII, IX, and X. Protein C & S ↓ after coumadin before the other factors
↓, resulting in a highly hypercoagulable kingdom.
While performing a LAR for colon most cancers in a affected person on continual dialysis,
you note a widespread amount of bloody oozing from your dissection plane. All of the
subsequent are real of uremic induced platelet disorder besides:
a. Down regulates GpIb
b. Down regulates GpIIb/IIIa
c. Stimulates von Willebrand's thing launch
d. Treatment of preference is dialysis - ANS(c)
Uremia downregulates GpIb, GpIIb/IIIa, and vWF
Dialysis is the preliminary remedy of preference for uremic coagulopathy. Other healing
options encompass DDAVP and conjugated estrogens (which stimulate the discharge of
component VIII and vWF).
The most not unusual blood transfusion response is:
a. Clerical blunders leading to ABO incompatibility
b. Transfusion related ALI
c. Delayed hemolysis from response to minor antigens
d. Febrile non-hemolytic transfusion response - ANS(d)
Occurs from WBCs in the donor blood
Clerical blunders leading to ABO incompatibility is the maximum not unusual transfusion
reaction main to DEATH
Prevention of febrile non-hemolytic transfusion reaction in patients requiring blood involves:
a. Heating blood to smash the WBCs
b. Prophylactic antibiotics
c. NSAIDs
d. Leukocyte filter - ANS(d)
2 weeks after a whipple operation, your affected person continues to have early satiety with
oral intake. You determine to start metoglopramide (Reglan) and erythromycin. What
receptor does erythromycin bind to growth gastrointestinal motility? - ANSMotilin (discovered
generally inside the belly, duodenum, and colon)
Proteins are synthesized from:
a. MRNA
b. TRNA
c. DsDNA
d. SsDNA - ANSmRNA
1 week after an APR, our affected person develops urosepsis requiring extent resuscitation,
antibiotics, and moderate quantities of levophed and vasopressin. E. Coli grows out from the
blood cultures. What part of the lipopolysaccharide complicated accounts for its toxicity -
ANSLipid A (with gram negative sepsis; stimulator of TNFα)
Steroid hormones:
a. Bind a receptor at the plasma membrane and spark off a plasma membrane enzyme
b. Bind a cytoplasmic receptor, input the nucleus, and affect transcription of proteins
c. Bind a receptor in the nucleus and have an effect on transcription of proteins
d. Do no longer enter the mobile - ANS(b)
Bind a receptor within the cellular cytoplasm, input the nucleus as a steroid-receptor
complex, and affect transcription of proteins
4 days after an Ivor-Lewis esophagectomy, you decide to begin enteral tube feeding thru a
J-tube. The long chain fatty acids contained inside the tube feeds:
a. Enter the movement thru the portal gadget
b. Enter the flow through lymphatics
c. Are only synthesized in the frame
d. Are now not found in chylomicrons - ANS(b)
Long-chain FAs input the body thru terminal lacteals (absorption via the lymphatic gadget)
both as unfastened LCFAs or as chylomicrons
Medium- and quick-chain FAs at the side of proteins/CHO input thru the portal flow
Cells divide in the course of what segment of the cell cycle?
,A. G1
b. S
c. G2
d. M - ANS(d)
Cells divide all through the M segment (most radiosensitive)
Cell cycle period is determined through what section of the cell cycle?
A. G1
b. S
c. G2
d. M - ANS(a)
G1 ↔ G0 phase determines cell cycle period (most variable cellular length)
Most RNA/protein synthesis
Of the subsequent, that is the maximum crucial thing inside the neovascularization of tumor
metastases?
A. HER receptor
b. VEGF receptor
c. Neu receptor
d. FGF receptor - ANS(d)
Vascular endothelial increase component (VEGF) receptor
For its anticoagulation results, heparin binds:
a. Protein C
b. Protein S
c. Anti-thrombin III
d. Factor VII - ANS(c)
ATIII (heparin-ATIII complicated binds thrombin, factor IX, element X, and component XI)
7 days after a kidney transplant, your affected person develops intense acute rejection with
vasculitis on biopsy. You determine to start the monoclonal antibody OKT3. Monoclonal
antibodies:
a. Bind 1 epitope at one web page
b. Bind 1 epitope at multiple sites
c. Bind a couple of epitopes on a single antigen
d. Bind multiple epitopes on a couple of antigens - ANS(a)
They bind one epitope at the precise identical binding web site
, You start coumadin on a affected person with a pulmonary embolus. Three days later, he
begins sloughing off skin across his legs and arms. All of the subsequent are authentic of
this sufferers most possibly situation except:
a. This probable might had been avoided by way of beginning heparin earlier than coumadin
b. Patients with protein C deficiency are greater liable to this hassle
c. The skin sloughing is resulting from pores and skin necrosis
d. This is probable due to hemophilia A - ANS(d)
Coumadin-brought on pores and skin necrosis takes place in patients started on coumadin
without being given heparin first. It consequences from a noticeably hypercoagulable
kingdom that could arise in some individuals due to the shorter half-life of protein C & S
compared to factors II, VII, IX, and X. Protein C & S ↓ after coumadin before the other factors
↓, resulting in a highly hypercoagulable kingdom.
While performing a LAR for colon most cancers in a affected person on continual dialysis,
you note a widespread amount of bloody oozing from your dissection plane. All of the
subsequent are real of uremic induced platelet disorder besides:
a. Down regulates GpIb
b. Down regulates GpIIb/IIIa
c. Stimulates von Willebrand's thing launch
d. Treatment of preference is dialysis - ANS(c)
Uremia downregulates GpIb, GpIIb/IIIa, and vWF
Dialysis is the preliminary remedy of preference for uremic coagulopathy. Other healing
options encompass DDAVP and conjugated estrogens (which stimulate the discharge of
component VIII and vWF).
The most not unusual blood transfusion response is:
a. Clerical blunders leading to ABO incompatibility
b. Transfusion related ALI
c. Delayed hemolysis from response to minor antigens
d. Febrile non-hemolytic transfusion response - ANS(d)
Occurs from WBCs in the donor blood
Clerical blunders leading to ABO incompatibility is the maximum not unusual transfusion
reaction main to DEATH
Prevention of febrile non-hemolytic transfusion reaction in patients requiring blood involves:
a. Heating blood to smash the WBCs
b. Prophylactic antibiotics
c. NSAIDs
d. Leukocyte filter - ANS(d)
