BIO2015
Human Pathophysiology
COMPLETE MIDTERM GUIDE
© SU 2024/2025
,1. Multiple Choice: Which of the following mechanisms is
primarily involved in the development of anemia of chronic
disease?
A) Increased erythropoietin production
B) Decreased iron availability
C) Enhanced iron absorption
D) Increased red blood cell lifespan
Correct Answer: B) Decreased iron availability
Rationale: Anemia of chronic disease is often associated with
decreased iron availability due to inflammatory cytokines affecting
iron metabolism and impairing erythropoiesis.
2. Fill-in-the-Blank: __________ is the term used to describe the
accumulation of fluid in the peritoneal cavity, commonly seen in
patients with liver cirrhosis.
Correct Answer: Ascites
Rationale: Ascites refers to the buildup of fluid in the peritoneal
cavity, which can occur due to increased portal pressure and
hypoalbuminemia in liver cirrhosis.
3. True/False: The presence of Reed-Sternberg cells is a definitive
diagnostic feature of Hodgkin's lymphoma.
© SU 2024/2025
, Correct Answer: True
Rationale: Reed-Sternberg cells are characteristic of Hodgkin's
lymphoma and their presence is essential for diagnosis.
4. Multiple Response: Select all that apply. Which of the following
are potential complications of myocardial infarction?
A) Arrhythmias
B) Cardiac tamponade
C) Left ventricular aneurysm
D) Stroke
Correct Answers: A) Arrhythmias, B) Cardiac tamponade, C)
Left ventricular aneurysm
Rationale: Complications of myocardial infarction can include
arrhythmias, cardiac tamponade, and left ventricular aneurysm.
Stroke is not a direct complication but may occur separately due to
other cardiovascular issues.
5. Multiple Choice: What is the primary pathophysiological
process of type 1 diabetes mellitus?
A) Insulin resistance
B) Beta-cell destruction
C) Excessive glucagon secretion
D) Decreased glucose uptake by cells
© SU 2024/2025
Human Pathophysiology
COMPLETE MIDTERM GUIDE
© SU 2024/2025
,1. Multiple Choice: Which of the following mechanisms is
primarily involved in the development of anemia of chronic
disease?
A) Increased erythropoietin production
B) Decreased iron availability
C) Enhanced iron absorption
D) Increased red blood cell lifespan
Correct Answer: B) Decreased iron availability
Rationale: Anemia of chronic disease is often associated with
decreased iron availability due to inflammatory cytokines affecting
iron metabolism and impairing erythropoiesis.
2. Fill-in-the-Blank: __________ is the term used to describe the
accumulation of fluid in the peritoneal cavity, commonly seen in
patients with liver cirrhosis.
Correct Answer: Ascites
Rationale: Ascites refers to the buildup of fluid in the peritoneal
cavity, which can occur due to increased portal pressure and
hypoalbuminemia in liver cirrhosis.
3. True/False: The presence of Reed-Sternberg cells is a definitive
diagnostic feature of Hodgkin's lymphoma.
© SU 2024/2025
, Correct Answer: True
Rationale: Reed-Sternberg cells are characteristic of Hodgkin's
lymphoma and their presence is essential for diagnosis.
4. Multiple Response: Select all that apply. Which of the following
are potential complications of myocardial infarction?
A) Arrhythmias
B) Cardiac tamponade
C) Left ventricular aneurysm
D) Stroke
Correct Answers: A) Arrhythmias, B) Cardiac tamponade, C)
Left ventricular aneurysm
Rationale: Complications of myocardial infarction can include
arrhythmias, cardiac tamponade, and left ventricular aneurysm.
Stroke is not a direct complication but may occur separately due to
other cardiovascular issues.
5. Multiple Choice: What is the primary pathophysiological
process of type 1 diabetes mellitus?
A) Insulin resistance
B) Beta-cell destruction
C) Excessive glucagon secretion
D) Decreased glucose uptake by cells
© SU 2024/2025
