Edition by Sheila L. Videbeck All Chapters 1-24
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They combat the extrapyramidal side effects of the neuroleptic drug. - ANSWER A
nurse is administering medications to clients on a psychiatric unit. What does the
nurse identify as the reason that so many psychiatric clients are given the drug
benztropine or trihexyphenidyl in conjunction with the phenothiazine-derivative
neuroleptic medications?
Torticollis - ANSWER acute dystonia that involves muscle spasms of the neck;
develops within 1 to 5 days after beginning therapy with a conventional antipsychotic
Tardive dyskinesia - ANSWER involuntary repetitious tonic muscular spasms that
involve the face, tongue, lips, limbs, and trunk; takes several months to years to
develop after the start of therapy with a conventional antipsychotic
d/c if observed, may be reversible
Pseudoparkinsonism - ANSWER extrapyramidal tract response that includes
masklike facies, shuffling gait, pill-rolling tremors, stooped posture, and drooling;
develops within several days to 1 month after the start of therapy with a conventional
antipsychotic
Neuroleptic malignant syndrome - ANSWER severe, potentially fatal response to
conventional antipsychotics
caused by acute reduction in dopamine activity, precipitating hyperthermia/pyrexia,
tachycardia, tachypnea, unstable blood pressure, dyskinesia, incontinence,
decreased level of consciousness
Clozapine - ANSWER 2nd gen atypical antipsychotic drug that is more effective
than other second-generation antipsychotics
Seizures, sedation, and akathisia are common side effects
contraindicated in clients with bone marrow depression
may cause agranulocytosis, the client's white blood cell (WBC) count should be
monitored weekly. The drug should be discontinued if the count falls below
3,000/mm 3
use with caution in clients with seizures
Isocarboxazid - ANSWER MAOI
, Circulatory collapse is associated with toxicity
fluphenazine - ANSWER typical antipsychotic
Acute dystonic reactions such as tremors, dyskinesia, and akathisia are observable
side effects
decreased salivating
haloperidol - ANSWER antipsychotic drug used in the long-term treatment of
psychosis
Gynecomastia is one of the adverse effects of this drug
Potential adverse effects: pseudoparkinsonism and urinary retention related to
extrapyramidal syndrome
Ziprasidone - ANSWER atypical antipsychotic
contraindicated in clients with a history of dysrhythmias
Akathisia - ANSWER Motor restlessness
can be treated with an antiparkinsonian or anticholinergic drug while the
antipsychotic medication is continued
acute dystonia - ANSWER Acute, often painful, sustained contraction of muscles
typically occurs 2 to 5 days after the introduction of antipsychotic medications
can be treated with an antiparkinsonian or anticholinergic drug while the
antipsychotic medication is continued
Disulfiram - ANSWER aversion therapy for alcohol addiction/abuse
cannot tolerate alcohol when on it
consuming alcohol while taking it will cause a severe reaction:
nausea, vomiting, hypotension, headache, tachycardia, tachypnea, and flushing
Duloxetine - ANSWER used to treat both generalized anxiety disorder and
depression
can worsen uncontrolled angle-closure glaucoma
Lithium - ANSWER used to treat manic episodes but is contraindicated in clients
with renal or cardiovascular disease
therapeutic range of serum levels is 0.5 to 1.5