At most institutions, who must review and monitor the animal use protocols at an institution?
a. Institutional Animal Care and Use Committee
b. Institutional Official
c. Office of Laboratory Animal Welfare
d. Attending Veterinarian Correct answer-a. IACUC
What is the term described in the 3Rs for designing an experiment so that stress or pain to an
animal is minimized?
a. Reduction
b. Refinement
c. Replacement
d. Reconstitution Correct answer-b. Refinement
Using cell or tissue culture or mathematical models in the experiment whenever possible and
substituting "lower" species for "higher" mammalian species are examples of which of the 3Rs
principles?
a. Reduction
b. Refinement
, ALAT Chapter 2 Practice Test with Complete Solutions
c. Replacement
d. Reconstitution Correct answer-c. Replacement
Using the minimum number of animals that will serve a useful purpose, yet yield statistically
sound data and produce scientific benefit demonstrates which principle?
a. Reduction
b. Refinement
c. Replacement
d. Reconstitution Correct answer-a. Reduction
Which document is named by the Guide and PHS Policy as the one that must be followed when
euthanizing research animals?
a. OLAW Guide to Euthanasia
b. USDA Panel on Euthanasia
c. Animal Welfare Act
d. AVMA Guidelines on Euthanasia Correct answer-d. AVMA Guidelines on Euthanasia
Beyond food, water, shelter, and healthcare requirements, to comply with the AWA, what must
be
provided to dogs in a laboratory animal research facility?