PCAM FINAL MATERIAL
| 100 STUDY
QUESTIONS | WITH
COMPLETE ANSWERS,
GRADED A+
PCAM
Evatee 8/3/24 PCAM
,PCAM FINAL MATERIAL | 100 STUDY
QUESTIONS | WITH COMPLETE ANSWERS,
GRADED A+
What can you tell a colleague about drug-supplement interactions?
A) In vitro studies are reliable indicators of the risk of interactions in humans
B) The elderly population may be at the greatest risk for a potential infection
C) Dietary supplement manufacturers typically test for potential interactions
with drugs
D) Prescription drugs are required to test for potential interactions with
supplements Answer - B
What is an example of a pharmacokinetic interaction?
A) SAMe (S-adenosyl-methionine) increases serotonin levels, and combining it
with a selective serotonin reuptake inhibitor (SSRI) might cause serotonin
syndrome
B) Flaxseed oil might decrease platelet aggregation and prolonged use of
flaxseed with aspirin or warfarin might increase the risk of bleeding
C) Taking large amounts of licorice increases potassium loss and combining it
with a diuretic may result in hypokalemia and hypotension
D) Orange juice inhibits organic anion transporting polypeptide (OATP) in the
gut which might decrease the absorption of fexofenadine Answer - D
,Based on the system for evaluating the significance of drug-supplement
interactions described in this course, what would the overall rating be for an
interaction that is "probable" and has "moderate" severity?
A) Major
B) Moderate
C) Minor
D) Insignificant Answer - B
What is the best way to prevent an interaction between grapefruit and CYP3A4
substrates?
A) Consume only white flesh grapefruit and avoid pink flesh
B) Separate consuming grapefruit and CYP3A4 substrate drugs by 4 hours
C)Avoid grapefruit juice , but it's okay to eat whole grapefruit
D) Avoid grapefruit and grapefruit products when taking CYP3A4 substrate
drugs Answer - D
A transplant patient stabilized on cyclosporine mentions to his healthcare
provider that he feels depressed. He wants to try St. John's Wort. How would
you counsel this patient?
A) Do not take St. John's wort
B) It's okay to take St. John's wort as long as cyclosporine levels are monitored
C) St. John's wort is a better choice than a conventional SSRI
D) St. John's wort does not interact with cyclosporine, it is okay to take Answer
-A
, A 32-year-old female asks you if she should take an allicin-rich garlic
supplement for lower cholesterol. Her current medications include an oral
contraceptive, ibuprofen as needed for menstrual discomfort, and calcium.
What would you recommend for this patient?
A) She should separate administration of ibuprofen and garlic by at least 2
hours
B) Don't use calcium and garlic at the same time because it can decrease the
effectiveness of garlic
C) Use a backup form of birth control while taking allicin-rich garlic
D) Garlic may cause severe stomach discomfort when taken with an oral
contraceptive Answer - C
A patient was prescribed ciprofloxacin for a lower respiratory tract infection.
She has heard that some people drink tea and honey to battle similar
infections. She doesn't like drinking tea but she is planning to start taking green
tea capsules instead. How would you counsel this patient?
A) It's okay to take the green tea supplement
B) Do not take the green tea supplement, but it's okay to drink green tea
C) Do not take the green tea supplement, and do not drink green tea while
taking ciprofloxacin
D) Take the green tea supplement, but separate it from the ciprofloxacin by 2
hours Answer - C
Which is a clinically significant drug-supplement interaction?
A) Calcium and clopidogrel
B) Fish oil and aspirin
| 100 STUDY
QUESTIONS | WITH
COMPLETE ANSWERS,
GRADED A+
PCAM
Evatee 8/3/24 PCAM
,PCAM FINAL MATERIAL | 100 STUDY
QUESTIONS | WITH COMPLETE ANSWERS,
GRADED A+
What can you tell a colleague about drug-supplement interactions?
A) In vitro studies are reliable indicators of the risk of interactions in humans
B) The elderly population may be at the greatest risk for a potential infection
C) Dietary supplement manufacturers typically test for potential interactions
with drugs
D) Prescription drugs are required to test for potential interactions with
supplements Answer - B
What is an example of a pharmacokinetic interaction?
A) SAMe (S-adenosyl-methionine) increases serotonin levels, and combining it
with a selective serotonin reuptake inhibitor (SSRI) might cause serotonin
syndrome
B) Flaxseed oil might decrease platelet aggregation and prolonged use of
flaxseed with aspirin or warfarin might increase the risk of bleeding
C) Taking large amounts of licorice increases potassium loss and combining it
with a diuretic may result in hypokalemia and hypotension
D) Orange juice inhibits organic anion transporting polypeptide (OATP) in the
gut which might decrease the absorption of fexofenadine Answer - D
,Based on the system for evaluating the significance of drug-supplement
interactions described in this course, what would the overall rating be for an
interaction that is "probable" and has "moderate" severity?
A) Major
B) Moderate
C) Minor
D) Insignificant Answer - B
What is the best way to prevent an interaction between grapefruit and CYP3A4
substrates?
A) Consume only white flesh grapefruit and avoid pink flesh
B) Separate consuming grapefruit and CYP3A4 substrate drugs by 4 hours
C)Avoid grapefruit juice , but it's okay to eat whole grapefruit
D) Avoid grapefruit and grapefruit products when taking CYP3A4 substrate
drugs Answer - D
A transplant patient stabilized on cyclosporine mentions to his healthcare
provider that he feels depressed. He wants to try St. John's Wort. How would
you counsel this patient?
A) Do not take St. John's wort
B) It's okay to take St. John's wort as long as cyclosporine levels are monitored
C) St. John's wort is a better choice than a conventional SSRI
D) St. John's wort does not interact with cyclosporine, it is okay to take Answer
-A
, A 32-year-old female asks you if she should take an allicin-rich garlic
supplement for lower cholesterol. Her current medications include an oral
contraceptive, ibuprofen as needed for menstrual discomfort, and calcium.
What would you recommend for this patient?
A) She should separate administration of ibuprofen and garlic by at least 2
hours
B) Don't use calcium and garlic at the same time because it can decrease the
effectiveness of garlic
C) Use a backup form of birth control while taking allicin-rich garlic
D) Garlic may cause severe stomach discomfort when taken with an oral
contraceptive Answer - C
A patient was prescribed ciprofloxacin for a lower respiratory tract infection.
She has heard that some people drink tea and honey to battle similar
infections. She doesn't like drinking tea but she is planning to start taking green
tea capsules instead. How would you counsel this patient?
A) It's okay to take the green tea supplement
B) Do not take the green tea supplement, but it's okay to drink green tea
C) Do not take the green tea supplement, and do not drink green tea while
taking ciprofloxacin
D) Take the green tea supplement, but separate it from the ciprofloxacin by 2
hours Answer - C
Which is a clinically significant drug-supplement interaction?
A) Calcium and clopidogrel
B) Fish oil and aspirin
