ATI Pharmacology Questions with correct answers
Rocephin belongs to what class of anti-infectives? Correct Answer - 3rd generation
cephalosporin
Rocephin, as a cephalosporin, is contraindicated in pts. with an allergy to this class of anti-infectives Correct Answer - penicillin
valporic acid (Depakene) indicated for Correct Answer - seizures
valporic acid (Depakene) may carry adverse side effects such as Correct Answer - thrombocytopenia, prolonged bleeding time, life-threatening hepatotoxicity
valporic acid (Depakene) may have toxic effects on this organ Correct Answer - liver
chlorothiazide (Diuril) puts one at risk of this electrolyte imbalance Correct Answer - hypokalemia
lactulose (Cephulac) is a laxative given to promote the excretion of Correct Answer - ammonia
What doe lactulose (Cephulac) do? Correct Answer - discourages growth of bacteria, traps ammonia in the gut, expels ammonia from the colon
What happens to ammonia levels in liver failure? Correct Answer - ammonia levels increase in liver failure toxic megacolon is Correct Answer - a condition characterized by paralysis of colonic peristalsis resulting in rapid dilatation of the bowel -- the bowel gets bigger
as feces is trapped; symptoms include tachycardia, fever, abd tenderness/cramping,
reduction/cessation of diarrhea
filgastrim (Neupogen) is used with clients who have this decreased count on their CBC Correct Answer - neutophils
proteinuria is related to what type of toxicity? Correct Answer - nephrotoxicity
gentamicin sulface (Garamycin) is related to this type of toxicity Correct Answer - nephrotoxicity
metoclopramide (Reglan) is used to Correct Answer - control vomiting associated with chemotherapy, postop vomiting, etc.
tamoxifen (Nolvadex) is used in tx of breast cancer; it belongs to this class of drugs: Correct Answer - anti-estrogenic, antineoplastics
amantadine (Symmetrel) belongs to what class of drugs used to treat extrapyramidal side effects Correct Answer - antiparkinsonian drugs
Hydroxyzine (Vistaril) belongs to which therapeutic classes Correct Answer - Antianxiety agents, antihistamines, sedative/hypnotics
This is a common side effect of hydroxyzine (Vistaril) Correct Answer - Dry mouth Why return TPN to pharmacy when noticing a marked separation of oil droplets from rest of solution? Correct Answer - This is called cracking of lipid emulsion, and renders the solution unusable.
Does bismuth subsalicylate (Pepto Bismol) have anti-infective properties against H. pylori? Correct Answer - Yes
What common GI disorder is caused by H. pylori? Correct Answer - Peptic ulcer disease
Should glucocorticoids be taken on an empty stomach? Correct Answer - No, because they can cause severe GI distress and lead to ulcer formation
Name an acceptable means of reducing the side effects of long term oral glucocorticoid therapy Correct Answer - Schedule the medication on alternate days
Why avoid tricyclic antidepressants during pregnancy? Correct Answer - They are associated with fetal anomalies, especially during the first trimester
Amitriptyline (Elavil) is what type of medication? Correct Answer - Tricyclic antidepressant
Risedronate (Actonel) Correct Answer - Bisphosphonate used in osteoporosis; take
first thing in morning with glass water at least 30 mins prior to eating
Streptomycin and furosemide taken together increase the risk for this type of toxicity Correct Answer - Ototoxicity
Rocephin belongs to what class of anti-infectives? Correct Answer - 3rd generation
cephalosporin
Rocephin, as a cephalosporin, is contraindicated in pts. with an allergy to this class of anti-infectives Correct Answer - penicillin
valporic acid (Depakene) indicated for Correct Answer - seizures
valporic acid (Depakene) may carry adverse side effects such as Correct Answer - thrombocytopenia, prolonged bleeding time, life-threatening hepatotoxicity
valporic acid (Depakene) may have toxic effects on this organ Correct Answer - liver
chlorothiazide (Diuril) puts one at risk of this electrolyte imbalance Correct Answer - hypokalemia
lactulose (Cephulac) is a laxative given to promote the excretion of Correct Answer - ammonia
What doe lactulose (Cephulac) do? Correct Answer - discourages growth of bacteria, traps ammonia in the gut, expels ammonia from the colon
What happens to ammonia levels in liver failure? Correct Answer - ammonia levels increase in liver failure toxic megacolon is Correct Answer - a condition characterized by paralysis of colonic peristalsis resulting in rapid dilatation of the bowel -- the bowel gets bigger
as feces is trapped; symptoms include tachycardia, fever, abd tenderness/cramping,
reduction/cessation of diarrhea
filgastrim (Neupogen) is used with clients who have this decreased count on their CBC Correct Answer - neutophils
proteinuria is related to what type of toxicity? Correct Answer - nephrotoxicity
gentamicin sulface (Garamycin) is related to this type of toxicity Correct Answer - nephrotoxicity
metoclopramide (Reglan) is used to Correct Answer - control vomiting associated with chemotherapy, postop vomiting, etc.
tamoxifen (Nolvadex) is used in tx of breast cancer; it belongs to this class of drugs: Correct Answer - anti-estrogenic, antineoplastics
amantadine (Symmetrel) belongs to what class of drugs used to treat extrapyramidal side effects Correct Answer - antiparkinsonian drugs
Hydroxyzine (Vistaril) belongs to which therapeutic classes Correct Answer - Antianxiety agents, antihistamines, sedative/hypnotics
This is a common side effect of hydroxyzine (Vistaril) Correct Answer - Dry mouth Why return TPN to pharmacy when noticing a marked separation of oil droplets from rest of solution? Correct Answer - This is called cracking of lipid emulsion, and renders the solution unusable.
Does bismuth subsalicylate (Pepto Bismol) have anti-infective properties against H. pylori? Correct Answer - Yes
What common GI disorder is caused by H. pylori? Correct Answer - Peptic ulcer disease
Should glucocorticoids be taken on an empty stomach? Correct Answer - No, because they can cause severe GI distress and lead to ulcer formation
Name an acceptable means of reducing the side effects of long term oral glucocorticoid therapy Correct Answer - Schedule the medication on alternate days
Why avoid tricyclic antidepressants during pregnancy? Correct Answer - They are associated with fetal anomalies, especially during the first trimester
Amitriptyline (Elavil) is what type of medication? Correct Answer - Tricyclic antidepressant
Risedronate (Actonel) Correct Answer - Bisphosphonate used in osteoporosis; take
first thing in morning with glass water at least 30 mins prior to eating
Streptomycin and furosemide taken together increase the risk for this type of toxicity Correct Answer - Ototoxicity
