Immunology Exam 1 Questions With Verified Answers

Immunology Exam 1 Questions With Verified Answers primary lymphoid organs bone marrow and thymus secondary lymphoid organs lymph nodes, spleen, Peyer's patches Hematopoietic stem cells are multipotent stem cells NK cells secrete perforins and granzymes NK cells release this for communication cytokines Innate immune cells neutrophils, macrophages, DC cells, mast cells, eosinophils, basophils, NK cells Adaptive immune cells T cells and B cells B cells and T cells contain which receptors BCRs and TCRs respectively Cytokines Secreted by cells for communication Chemokines cytokine that helps movement, migration and enhancement of adaptive immunity tumor necrosis factor cytokine that promotes anti-tumor and inflammation What is humoral immunity? antibody-mediated immunity What are the antibody isotypes IgA, IgE, IgD, IgG, IgM What are antibody idiotypes? variable regions (Fab) What antibody isotype is found in mucosal immunity? IgA what antibody is most common IgG Which antibody is first released IgM What determine if BCRs are membrane bound or secreted as antibodies mRNA splicing PRRs are located on innate immune cells Toll-like receptors (TLRs) plasma membrane PRRs for extracellular pathogens NOD-like receptors (NLRs) Cytoplasmic PRRs for intracellular pathogens Endosomal TLRs DNA/RNA pathogens Neutrophils phagocytes responsible for bacteria and some viruses the most abundant WBC is neutrophil DC cells are Phagocytes and antigen presenting cells DC cells are located in the blood and peripheral tissues Macrophages phagocytes located in tissues Which cells are antigen presenting cells B cells, macrophages, dendritic cells