Pharmacology 1st Semester Nursing STLCC Exam With Complete Solution 2024.

Pharmacology 1st Semester Nursing STLCC Exam With Complete Solution 2024. At what phase during drug evaluation does the drug first hit the clinical market? A. Preclinical Trial B. Phase I C. Phase II D. Phase III E. Phase IV - ANSWER D. Phase III During Preclinical Trials the chemical is tested in a lab on animals to determine its therapeutic and toxic effects. During Phase I the drug is then tested on human volunteers that are typically compensated. During Phase II the drug is tested on patients that the drug is designed to treat and is more selective than Phase I. During Phase III the drug will first hit the clinical market. During Phase IV the drug is continued to be evaluated and monitored. What an example of a Generic Drug name? (Select all the apply) A. Tylenol B. Ibuprofen Pharmacology 1st Semester Nursing STLCC Exam With Complete Solution 2024 C. Acetaminophen D. Excedrin - ANSWER B. Ibuprofen C. Acetaminophen Tylenol and Excedrin are examples of brand names How long is a standard patent on a drug once it hits the market before other drug companies can start to produce the drug? A. 2 years B. 3 years C. 5 years D. 10 years - ANSWER C. 5 years What is the term used to describe how a drug moves through the body? A. Pharmacotherapeutics B. Bioavailability C. Biotransformation D. Pharmacokinetics - ANSWER D. Pharmacokinetics Pharmacotherapeutics is a branch of pharmacology that uses drugs to treat, prevent, and diagnose disease. Bioavailability is the concentration of a drug that actually reaches the systemic circulation Biotransformation is the alteration of a drug structure, changing a drug from it's original form to an activated form Pharmacokinetics refers to the action of a drug as it moves through the body kinetics meaning movement What organ in the body does biotransformation take place? A. Kidney B. Liver C. Brain D. Small intestine - ANSWER B. Liver The liver is where the body does a good portion of it's metabolism The kidney is the most common place of excretion in the body. Where else can the body excrete from? (Select all the apply) A. Skin B. Saliva C. Lungs D. Bile E. Feces - ANSWER All of the listed the body excrete from Which can pass through the blood-brain barrier? A. Drugs that are fat soluble B. Drugs that are water soluble - ANSWER A. Drugs that are fat soluble.