Exam 2 – Neuropharmacology || A+ Verified Solutions.

Neurotransmitters correct answers •Glutamate •GABA •Acetylcholine •Dopamine •Norepinephrine •Serotonin •Opioid Peptides •Endocannabinoids Glutamate correct answers excitatory neurotransmitter everywhere too much = seizures GABA correct answers inhibitory neurotransmitter everywhere ALCOHOL: acts on both GABA and Glutamate correct answers increases GABA activity (agonist), decreases Glu activity (antagonist) Acetylcholine correct answers Sent from basal forebrain Sent to: cortex, amygdala, hippocampus, skeletal muscles, PNS Major role: in CNS: learning and memory modulation; in PNS: motor control, parasympathetic activity Dopamine correct answers Sent from: Midbrain: VTA and SN Sent to: cortex, basal ganglia and nucleus accumbens Major roles: reward, learning, motivation, movement Which NT characterizes: Most likely NT affected by recreational drugs Major deficiency in Parkinson's patients correct answers Dopamine Norepinephrine correct answers Sent from: Brainstem (locus coeruleus / LC) & midbrain (tegmentum) Sent to: cortex, thalamus, limbic system Major roles: alertness, mood, sexual behavior Catecholamine production correct answers Dopamine -> Norepinephrine -> Epinephrine Many drugs affect all three (chemically similar) Serotonin correct answers Sent from: Midbrain & brainstem (raphaenuclei) Sent to: throughout forebrain Major roles: sleep & wakefulness, mood, anxiety, hunger (LOTS!) SSRIs inhibit reuptake of _____ correct answers Serotonin