BioChem C785 - WGU - Module 3 - all questions with complete solutions

Hb (hemoglobin) binds to CO (carbon monoxide) with a higher affinity than oxygen and stabilizes the R (relaxed) state True When hemoglobin changes from the T to the R, it has a high affinity for oxygen True When hemoglobin changes from the R to T, it has a low affinity for oxygen True Cooperatively refers to structural changes that increases the affinity for oxygen in hemoglobin When the oxygen concentration is high, the heme shape is planar. When the oxygen concentration is low, the heme shape is bent shape. True The Bohr effect is a relationship between hemoglobin's oxygen binding behavior in conjunction with the pH of the surroundings. When the pH is low, hemoglobin has low affinity for oxygen and releases oxygen True Bohr effect is a relationship between hemoglobin's oxygen binding behavior in conjunction with the pH of the surroundings. When the pH is high, hemoglobin has high affinity for oxygen and binds oxygen. TrueRelative to the lungs, the pH in the peripheral tissues is lower, because the CO2 generated by metabolism is converted to bicarbonate, which releases proton (H+) True The Bohr effect is a relationship between hemoglobin's oxygen binding behavior in conjunction with the pH of the surroundings. When the H+ ion concentration increases, the pH of the solution decreases. True Myoglobin stores oxygen, whereas hemoglobin transports oxygen. Myoglobin has a higher affinity for oxygen compared to hemoglobin True Hemoglobin is an oxygen transport protein, whereas myoglobin is an oxygen storage protein. They exhibit different binding curves when plotted on a graph with total partial pressure of the oxygen (x-axis) plotted against the percentage saturation of hemoglobin (y-axis). What pattern of binding curves do these proteins exhibit? Hemoglobin has a sigmoidal curve whereas the myoglobin has a hyperbolic curve. Hemoglobin and myoglobin proteins bind to molecular oxygen. However, the protein part of the hemoglobin does not bind directly to the oxygen. Instead a specific atom helps bind the oxygen - Iron