USMLE STEP 1 Pharmacology exam 2023 with 100% correct answers

Increase vascular smooth muscle contraction, increase pupillary dilator muscle contraction (mydriasis), increase intestinal and bladder sphincter muscle contraction - correct answer What are the major functions of the α1 receptor? Decrease sympathetic outflow, decrease insulin release, decrease lipolysis, increase platelet aggregation, decrease aqueous humor production - correct answer What are the major functions of the α2 receptor? Increase heart rate, increase contractility, increase renin release, increase lipolysis - correct answer What are the major functions of the β1 receptor? Vasodilation, bronchodilation, increase lipolysis, increase insulin release, decrease uterine tone (tocolysis), ciliary muscle relaxation, increase aqueous humor production - correct answer What are the major functions of the β2 receptor? CNS, enteric nervous system - correct answer What are the major functions of the M1 receptor? Decrease heart rate and contractility of atria - correct answer What are the major functions of the M2 receptor? Increase exocrine gland secretions (e.g., lacrimal, salivary, gastric acid), increase gut peristalsis, increase bladder contraction, increase bronchoconstriction, pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accommodation) - correct answer What are the major functions of the M3 receptor? Relaxes renal vascular smooth muscle - correct answer What are the major functions of the D1 receptor? Modulates transmitter release, especially in the brain - correct answer What are the major functions of the D2 receptor? Increase nasal and bronchial mucus production, increase vascular permeability, contraction of bronchioles, pruritis, pain - correct answer What are the major functions of the H1 receptor? Increase gastric acid