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HESI A2 Biology Study Guide 2023

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HESI A2 Biology Study Guide 2023 Cellular respiration is the process inside of cells that converts nutrients (such as sugars, amino acids, and fatty acids) into ATP (adenosine triphosphate), which is used throughout the organism for energy. Large molecules are broken into smaller molecules, which releases both energy and waste. Aerobic respiration occurs in the presence of Oxygen and has four main stages:  Glycolysis: Larger sugar molecule is broken down into 2 smaller sugar molecules in the cytoplasm. Net gain of 2 ATP and 2 NADH  Formation of Acetyl CoA: Pyruvate undergoes oxidative decarboxylation to form Acetyl coenzyme A. 1 CO2 is released as waste. Net gain of 2 NADH.  Citric acid cycle: also known as Krebs cycle. The 2 small sugar molecules produced during glycolysis are oxidized forming new products. Gain of 2 ATP, 6 NADH, 2 FADH2.  Electron transport chain: redox reaction involving the electrons removed during glycolysis and the Krebs cycle. Protons are pumped across the mitochondrial membrane to form a gradient, which drives the synthesis of 34 ATP. Anaerobic respiration is a type of cellular respiration which occurs when oxygen is not present. This process is most commonly performed by bacteria and Achaea. These organisms use this process to obtain energy because they live in environments with low oxygen levels. Example: Achaea called methanogens use carbon dioxide to accept electrons. Methanogens can be found in soil and the digestive systems of animals called ruminants, which includes cows and sheep. Anaerobic respiration, similar to aerobic cellular respiration, uses electrons from the fuel molecules to pass through the electron transport chain, which drives ATP synthesis. The electron transport chain moves electrons to create a proton gradient that allows for the synthesis of ATP. Electron transport chains are used for extracting energy. This can happen in plants, where the energy from the sunlight is used to create glucose and oxygen through photosynthesis in the chloroplast. Eukaryotes perform this process in the mitochondria. Fermentation is another type of cellular respiration which occurs in the absence of Oxygen. Organisms capable of fermentation include prokaryotes, yeast, and multicellular organisms such as humans. Feature Aerobic Respiration Anaerobic Respiration Oxygen requirement Yes, always No, never Waste products Carbon dioxide and water Carbon dioxide and ethanol Efficiency in releasing energy from glucose Very efficient (most of the energy is released from glucose) Less efficient (some energy locked in ethanol is not released) Some energy released as heat Yes Yes, but less than that for aerobic respiration 3 | P a g e © 2017 All Rights Reserved. www.ReadyForTheHESI.org Antibiotics Antibiotics are a kind of medicine used to treat bacterial infections. Not all bacteria are bad or unhealthy. Humans and other animals actually have a healthy ecosystem of bacteria, called normal flora. These are the good kind of bacteria. Pathogenic bacteria are the type which can cause infection. Some bacteria will cause infection no matter where they are, but others are safe in some areas of the body, but become infectious when they wander to a new location in the body. An example of this is if the bacteria in the gut, or intestines, were to try and live in the bladder or another organ. This is what happens in case of a urinary tract infection. The body’s immune system must try to fight and destroy the invading bacteria

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