ONS ONCC Chemotherapy Immunotherapy Certificate Exam Latest Questions And Verified Answers

ONS ONCC Chemotherapy Immunotherapy Certificate Exam Latest Questions And Verified Answers Define mutations - ANSWER- Variations in the nucleotide sequence of a gene 3 main goals of treatment: - ANSWER- Cure Control Palliation Define neoadjuvant therapy - ANSWER- Treatment is given prior to surgery to shrink the tumor Define adjuvant therapy - ANSWER- Additional cancer treatment given after the primary treatment to lower the risk that the cancer reoccur Define conditioning/preparative therapy - ANSWER- Treatments used to prepare a patient for stem cell transplantation 2 types of conditioning therapies: - ANSWER- Myeloablative Nonmyeloablative Define dose density - ANSWER- Drug dose per unit of time Define dose intensity - ANSWER- Amount of drug delivered over time How is relative dose intensity (RDI) calculated? - ANSWER- By comparing the dose that the patient ACTUALLY received to the planned dose of the standard regimen How do alkylating agents work? - ANSWER- By causing a break in the DNA helix strand, interfering with DNA replication and causing cell death 3 subcategories of alkylating agents: - ANSWER- 1. Nitrogen mustards 2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as they work similarly) 3. Nitrosoureas Most common subcategory of alkylating agents: - ANSWER- Nitrogen mustards Common alkylating agents: - ANSWER- Cyclophosphamide (Cytoxan) Ifosfamide (Ifex) Bendamustine (Treanda) Common platinum-based agents: - ANSWER- Cisplatin (Platinol) Carboplatin (Paraplatin) What is unique about nitrosoureas agents? - ANSWER- Able to cross the blood- brain barrier; can be effective in treating some brain tumors