, Anatomy and Histology ofLymphatic System Neoplastic D
1
lymphatic systemfunction ->
lym
regulate balance of fluids and pla
filter the blood to
tiss
↳
lymphatic capillaries, vessels, lym
ducts and tracts
↳ 2
lymphatic
1 and
organs
co
=>
t
Lymphatic capillaries
collect interstitial fluid from
tissues,
organized in lymphatic
plexuses.
2:
lymphatic vessels Lymp Nodes Lymphocytes immune cells
->
->
↳
superficial a 10
->
- subcutaneous regions:axillary, pelvic, mediastinal... arise in
lymphoid organs -> mature -> se
layer of skin-> drain to deep contains:
lymphocytes, macrophages... divided into 3:T cells, B
->
cells, NK cells
vessels ↳ serve IT cells
lymphatic as a filtration point for lymph. "B cell: produce antibody and
↳
lymph from internal
carry organs.
both
#
sup, and deep lymph vessels go Lymphoid Organs
through lymph nodes.
y yo 2
affarent efferent y
↑
*Ye
I Bone Marrow:
B
cells:
originate and mature
Spleen. Tonsils. Vermiform
empty to
lymphatic
trunks
I cells:
only originate #Lymbocytes mature in
1"orgent
last location
final maturation (antigen-depen
T cells
lymphatic ducts S
=>
Thymus: mature
duct:r
1) rightlymphatic upperlimb,
head, chest development of called
lymphocytes
#
2) thoracic duct:rest of
body Antigen-native development. -
carried
↓ to functions
notes: bloodstream
vessels H
lymphatic fluid balance:drain extra fluid
->
one-way
-
I' (ex. s
lymp. lymph.organs large molecules
->
too
V.-> RO
pump. carry
lymp.r. -> have VALVES (preventflowing backward ->
immune survalance and fight pa
lymp. v. ->
Open system
#
lymphatic system -> route fat
of transportation, which ab
Clinical of
lymph
absorbed - packaged
fats ->
chylomicrons -lymph capillaries ->
lymph ve
->
=>
lymphoma -
enlarged
node
, Spleen
6:Germinal Centre
lymphocytes
-> White Pulp
↓
-
Red Pulp cells
T cells
B
Is -
cortex
-
paracortex
perishes PALS
-
-
Histology of Lymph Nodes 1
200-450 L.M.
medullary cords body
·
in our
Medulla sinuses
·
encapsulated Jelastin and collagen)
·afferentvessels the trabecular Trabecular
godeep by of cortex. continue
-> cords populated by B and T cells.
-> luminal surface sinuses
of contain Cortex trabecular sinus
reticular cells ->
final point
offiltration. -> made subscapular
of and cortical sinuses and lymph nodules
->
medullary sinuses are continuations
-Mph-> subscapulos. -> corticals.
cortical
of sinuses. They eventually APCs, antigens, lymphocytes lymphatic tissue
-
form efferent vessels.
through endothelium of cortical laye
->
Trabecular layer has T-helper, is cells -> more in than I cells.
cortex
* of values:
function
⑱
flow lymph- afferent L.N.- efferent. ->
Primary follice:small dormant lymphocytes.
-
of ->
secondary fullice:heterogenous mix activated large
-> of B cells.
-> Germinal Center Mantle Zone:inactive B cells, follicular dendritic cells (FD
have 3 zones: Montle, light, dark - ↓
meanstermeland
may mature into
or
plasma cells and
mode
stay in
LightZom:contain centrocytes
-
with
interact FDC
B cell, T-helper and help to
my clean up.
Dark Zone:contain centroblasts source cells
->
for
1
lymphatic systemfunction ->
lym
regulate balance of fluids and pla
filter the blood to
tiss
↳
lymphatic capillaries, vessels, lym
ducts and tracts
↳ 2
lymphatic
1 and
organs
co
=>
t
Lymphatic capillaries
collect interstitial fluid from
tissues,
organized in lymphatic
plexuses.
2:
lymphatic vessels Lymp Nodes Lymphocytes immune cells
->
->
↳
superficial a 10
->
- subcutaneous regions:axillary, pelvic, mediastinal... arise in
lymphoid organs -> mature -> se
layer of skin-> drain to deep contains:
lymphocytes, macrophages... divided into 3:T cells, B
->
cells, NK cells
vessels ↳ serve IT cells
lymphatic as a filtration point for lymph. "B cell: produce antibody and
↳
lymph from internal
carry organs.
both
#
sup, and deep lymph vessels go Lymphoid Organs
through lymph nodes.
y yo 2
affarent efferent y
↑
*Ye
I Bone Marrow:
B
cells:
originate and mature
Spleen. Tonsils. Vermiform
empty to
lymphatic
trunks
I cells:
only originate #Lymbocytes mature in
1"orgent
last location
final maturation (antigen-depen
T cells
lymphatic ducts S
=>
Thymus: mature
duct:r
1) rightlymphatic upperlimb,
head, chest development of called
lymphocytes
#
2) thoracic duct:rest of
body Antigen-native development. -
carried
↓ to functions
notes: bloodstream
vessels H
lymphatic fluid balance:drain extra fluid
->
one-way
-
I' (ex. s
lymp. lymph.organs large molecules
->
too
V.-> RO
pump. carry
lymp.r. -> have VALVES (preventflowing backward ->
immune survalance and fight pa
lymp. v. ->
Open system
#
lymphatic system -> route fat
of transportation, which ab
Clinical of
lymph
absorbed - packaged
fats ->
chylomicrons -lymph capillaries ->
lymph ve
->
=>
lymphoma -
enlarged
node
, Spleen
6:Germinal Centre
lymphocytes
-> White Pulp
↓
-
Red Pulp cells
T cells
B
Is -
cortex
-
paracortex
perishes PALS
-
-
Histology of Lymph Nodes 1
200-450 L.M.
medullary cords body
·
in our
Medulla sinuses
·
encapsulated Jelastin and collagen)
·afferentvessels the trabecular Trabecular
godeep by of cortex. continue
-> cords populated by B and T cells.
-> luminal surface sinuses
of contain Cortex trabecular sinus
reticular cells ->
final point
offiltration. -> made subscapular
of and cortical sinuses and lymph nodules
->
medullary sinuses are continuations
-Mph-> subscapulos. -> corticals.
cortical
of sinuses. They eventually APCs, antigens, lymphocytes lymphatic tissue
-
form efferent vessels.
through endothelium of cortical laye
->
Trabecular layer has T-helper, is cells -> more in than I cells.
cortex
* of values:
function
⑱
flow lymph- afferent L.N.- efferent. ->
Primary follice:small dormant lymphocytes.
-
of ->
secondary fullice:heterogenous mix activated large
-> of B cells.
-> Germinal Center Mantle Zone:inactive B cells, follicular dendritic cells (FD
have 3 zones: Montle, light, dark - ↓
meanstermeland
may mature into
or
plasma cells and
mode
stay in
LightZom:contain centrocytes
-
with
interact FDC
B cell, T-helper and help to
my clean up.
Dark Zone:contain centroblasts source cells
->
for
