SUBSTRATEN INDUCTOREN INHIBITOREN
P-gp - Digoxine - Rifamcipine - Verapamil, diltiazem
- DOAC - Sint-Janskruid - Amiodarone
- Colchicine - Anti-epileptica (carbamazepine) - Ciclosporine
- Posaconazol - Canagliflozine
- Macrolide antibiotica
- Itraconazol
- Ketoconazol
CYP1A2 - Theofylline - Roken - SSRI (fluvoxamine)
- Antipsychotica (clozapine) - Anti-epileptica (fenytoïne, carbamazepine) - Chinolonen
- Fenobarbital, primidon
- Rifamcipine
CYP2C9 - Fenytoïne - Sint-Janskruid - Azoolderivaten
- VKA - Anti-epileptica (fenytoïne, carbamazepine) (metronidazol, miconazol, voriconazol)
- Brivaracetam - Fenobarbital, primidon
- Fenobarbital - Rifamcipine
- Fluvastatine - Fluconazol
- Sulfonylureumderivaten
CYP2C19 - Fenytoïne - Sint-Janskruid - SSRI (fluvoxamine)
- Fenobarbital - Anti-epileptica (carbamazepine) - Topiramaat
- Benzodiazepines - Rifamcipine - Ticlopidine
- Clodipogrel - Azoolderivaten
CYP2D6 - Bètablokkers - Anti-epileptica (carbamazepine) - SSRI (fluoxetine/norfluoxetine/ paroxetine)
(genetisch - TCA - Rifamcipine - SNRI (duloxetine/venlafaxine)
polymorfisme) - SSRI’s - Bupropion
- Antipsychotica (risperidon & haloperidol) - Terbinafine
- Opiaten (oxycodon, codeïne, tramadol)
- Tamoxifen (activatie)
CYP3A4 - H1-antihistaminica (terfenadine) - Sint-Janskruid - Antimycotica, azoolderivaten
- Macrolide antibiotica - Anti-epileptica (fenytoïne, carbamazepine) (itraconazol, ketoconazol, posaconazol)
(clarithromycine, erythromycine) - Antiretrovirale middelen - Macrolide antibiotica
- Statines (simvastatine & atorvastatine) - Rifamycines (rifabutine, rifamcipine) - HIV protease inhibitoren
- Dihydropyridine, calciumantagonist - Fenobarbital, primidon - Ciclosporine
- Benzodiazepine (uitz: lorazepam & oxazepam) - Fluconazol - Pompelmoessap
- HIV protease inhibitoren - SSRI (fluvoxamine)
- Immuunsuppressiva - Verapamil
- Anticonceptie - Diltiazem
- Morfine - Aprepitant
- Tamoxifen (activatie)
- Digoxine
- Antipsychotica
- Carbamazepine
- Ivabradine
- DOAC
- Ciclosporine
- Tacrolimus, sirolimus
- Moederkoornalkaloïden
- Colchicine
- Itraconazol
P-gp - Digoxine - Rifamcipine - Verapamil, diltiazem
- DOAC - Sint-Janskruid - Amiodarone
- Colchicine - Anti-epileptica (carbamazepine) - Ciclosporine
- Posaconazol - Canagliflozine
- Macrolide antibiotica
- Itraconazol
- Ketoconazol
CYP1A2 - Theofylline - Roken - SSRI (fluvoxamine)
- Antipsychotica (clozapine) - Anti-epileptica (fenytoïne, carbamazepine) - Chinolonen
- Fenobarbital, primidon
- Rifamcipine
CYP2C9 - Fenytoïne - Sint-Janskruid - Azoolderivaten
- VKA - Anti-epileptica (fenytoïne, carbamazepine) (metronidazol, miconazol, voriconazol)
- Brivaracetam - Fenobarbital, primidon
- Fenobarbital - Rifamcipine
- Fluvastatine - Fluconazol
- Sulfonylureumderivaten
CYP2C19 - Fenytoïne - Sint-Janskruid - SSRI (fluvoxamine)
- Fenobarbital - Anti-epileptica (carbamazepine) - Topiramaat
- Benzodiazepines - Rifamcipine - Ticlopidine
- Clodipogrel - Azoolderivaten
CYP2D6 - Bètablokkers - Anti-epileptica (carbamazepine) - SSRI (fluoxetine/norfluoxetine/ paroxetine)
(genetisch - TCA - Rifamcipine - SNRI (duloxetine/venlafaxine)
polymorfisme) - SSRI’s - Bupropion
- Antipsychotica (risperidon & haloperidol) - Terbinafine
- Opiaten (oxycodon, codeïne, tramadol)
- Tamoxifen (activatie)
CYP3A4 - H1-antihistaminica (terfenadine) - Sint-Janskruid - Antimycotica, azoolderivaten
- Macrolide antibiotica - Anti-epileptica (fenytoïne, carbamazepine) (itraconazol, ketoconazol, posaconazol)
(clarithromycine, erythromycine) - Antiretrovirale middelen - Macrolide antibiotica
- Statines (simvastatine & atorvastatine) - Rifamycines (rifabutine, rifamcipine) - HIV protease inhibitoren
- Dihydropyridine, calciumantagonist - Fenobarbital, primidon - Ciclosporine
- Benzodiazepine (uitz: lorazepam & oxazepam) - Fluconazol - Pompelmoessap
- HIV protease inhibitoren - SSRI (fluvoxamine)
- Immuunsuppressiva - Verapamil
- Anticonceptie - Diltiazem
- Morfine - Aprepitant
- Tamoxifen (activatie)
- Digoxine
- Antipsychotica
- Carbamazepine
- Ivabradine
- DOAC
- Ciclosporine
- Tacrolimus, sirolimus
- Moederkoornalkaloïden
- Colchicine
- Itraconazol
