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Blood Bank ASCP EXAM Question and answer 2023 verified

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Blood Bank ASCP EXAM Question and answer 2023 verified What type of serological testing does the blood bank technologist perform when determining the blood group of a patient? phenotyping If anti-K reacts 3+ with a donor cell with a genotype KK and 2+ with a Kk cell, the antibody is demonstrating: Dosage Carla expresses the blood group antigens Fya, Fyb, and Xga. James shows expressions of none of these antigens. What factor(s) may account for the absence of these antigens in James? Gender and Race. The frequency of Duffy antigens Fya and Fyb varies with race. The Fy(a−b−) phenotype occurs in almost 70% of African Americans and is very rare in whites. The Xga antigen is X-linked and, therefore, expressed more frequently in women (who may inherit the antigen from either parent) than in men. Which of the following statements is true? A. An individual with the BO genotype is homozygous for B antigen B. An individual with the BB genotype is homozygous for B antigen C. An individual with the OO genotype is heterozygous for O antigen D. An individual with the AB phenotype is homozygous for A and B antigens B. An individual with the BB genotype is homozygous for B antigen Which genotype is heterozygous for C? A. DCe/dce B. DCE/DCE C. Dce/dce D. DCE/dCe A. DCe/dce Which genotype(s) will give rise to the Bombay phenotype? The Bombay phenotype will be expressed only when no H substance is present. The Oh type is expressed by the genotype hh. Bombays produce naturally occurring anti-H, and their serum agglutinates group O red cells in addition to red cells from groups A, B, and AB persons. Meiosis in cell division is limited to the ova and sperm producing four gametes containing what complement of DNA? 1N. Meiosis involves two nuclear divisions in succession resulting in four gametocytes each containing half the number of chromosomes found in somatic cells or 1N. A cell that is not actively dividing is said to be in: Interphase, The cell is engaged in metabolic activity. Chromosomes are not clearly discerned; however, nucleoli may be visible Which of the following describes the expression of most blood group antigens? Codominant What blood type is not possible for an offspring of an AO and BO mating? All are possible The alleged father of a child in a disputed case of paternity is blood group AB. The mother is group O and the child is group O. What type of exclusion is this? -Indirect/secondary/second order An indirect/secondary/second order exclusion occurs when a genetic marker is absent in the child but should have been transmitted by the alleged father. In this case, either A or B should be present in the child. If the frequency of gene Y is 0.4 and the frequency of gene Z is 0.5, one would expect that they should occur together 0.2 (20%) of the time. In actuality, they are found together 32% of the time. This is an example of: Linkage disequilibrium. Linkage disequilibrium is a phenomenon in which alleles situated in close proximity on a chromosome associate with one another more than would be expected from individual allelic frequencies.

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