ONS Chemotherapy Immunotherapy Certificate 2023 Exam Study Guide

3 major phases of cell division: - Correct Answer Interphase Mitotic phase Cytokinesis 3 steps of interphase: - Correct Answer First growth phase (G1) Synthesis phase (S phase) Second growth phase (G2) 4 phases of mitosis: - Correct Answer Prophase Metaphase Anaphase Telophase Innate immunity: - Correct Answer Non-specific response, either: 1. Barrier (skin, mucous membranes, flora of skin/gut) 2. Cellular components (phagocytes, natural killer cells, granulocytes, macrophages) Adaptive immunity: - Correct Answer Follows innate immunity if unsuccessful. Memory immunity, including: 1. Humoral immunity (production of antibodies or immunoglobulins) 2. Cell mediated immunity (dependent upon T cells) 3. Regulatory T -cells (prevent autoimmune reactions and limit inflammatory responses) Define mutations - Correct Answer Variations in the nucleotide sequence of a gene 3 main goals of treatment: - Correct Answer Cure Control Palliation Define neoadjuvant therapy - Correct Answer Treatment is given prior to surgery to shrink the tumor Define adjuvant therapy - Correct Answer Additional cancer treatment given after the primary treatment to lower the risk that the cancer reoccur Define conditioning/preparative therapy - Correct Answer Treatments used to prepare a patient for stem cell transplantation 2 types of conditioning therapies: - Correct Answer Myeloablative Nonmyeloablative Define dose density - Correct Answer Drug dose per unit of time