Local Anesthesia and Vasoconstrictors in Dentistry questions with correct answers

What are 4 reasons why vasoconstrictors are used? CORRECT ANSWER 1. reduces potential overdose 2. increases duration 3. improves effectiveness 4. reduces blood flow What is the MRD of epinephrine for healthy patients? CORRECT ANSWER 0.2 mg per appointment What is the MRD of epinephrine for a cardiovascular compromised patient? CORRECT ANSWER 0.04 mg Epinephrine ____________________(increases or decreases) the rate of heart conditions. CORRECT ANSWER increases Levonodefrin is mostly paired with which other local anesthetic? CORRECT ANSWER mepivacaine Once absorbed, biotransformation is _______________, with expected plasma half-lives of about _________________. CORRECT ANSWER rapid, 1-2 minutes Which enzyme is responsible for biotransformation of epinephrine? CORRECT ANSWER catecholamine-O-methyltransferase (COMT) Which enzyme is responsible for further breakdown of epinephrine? CORRECT ANSWER monoamine oxidase (MAO)