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Fundamentals of clinical pharmacology

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Pharmacology basics This chapter focuses on the fundamental principles of pharmacology. It discusses basic information, such as how drugs are named and how they’re created. It also discusses the different routes by which drugs can be administered. Kinetics, dynamics, therapeutics This chapter also discusses what happens when a drug enters the body. This involves three main areas: pharmacokinetics (the absorption, distribution, metabolism, and excretion of a drug) pharmacodynamics (the biochemical and physical effects of drugs and the mechanisms of drug actions) pharmacotherapeutics (the use of drugs to prevent and treat diseases). In addition, the chapter provides an introduction to drug interactions and adverse drug reactions.

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Clinical Pharmacology Made
Incredibly Easy!
3rd Edition


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© 2009
Lippincott Williams & Wilkins
Philadelphia
323 Norristown Road, Suite 200, Ambler, PA 19002-
2756
978-0-7817-8938-7

0-7817-8938-9

The clinical treatments described and recommended in
this publication are based on research and consultation
with nursing, medical, and legal authorities. To the best
of our knowledge, these procedures reflect currently
accepted practice. Nevertheless, they can’t be
considered absolute and universal recommendations.
For individual applications, all recommendations must
be considered in light of the patient’s clinical condition
and, before administration of new or infrequently used
drugs, in light of the latest package-insert information.
The authors and publisher disclaim any responsibility
for any adverse effects resulting from the suggested
procedures, from any undetected errors, or from the
reader’s misunderstanding of the text.

,© 2009 by Lippincott Williams & Wilkins. All rights
reserved. This book is protected by copyright. No part
of it may be reproduced, stored in a retrieval system,
or transmitted, in any form or by any means’electronic,
mechanical, photocopy, recording, or otherwise’without
prior written permission of the publisher, except for
brief quotations embodied in critical articles and
reviews and testing and evaluation materials provided
by publisher to instructors whose schools have adopted
its accompanying textbook. Printed in the United States
of America. For information, write Lippincott Williams &
Wilkins, 323 Norristown Road, Suite 200, Ambler, PA
19002-2756.
CPIE3E—010608

Staff

Executive Publisher
Judith A. Schilling McCann, RN, MSN

Editorial Director
David Moreau
Clinical Director

Joan M. Robinson, RN, MSN
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Mary Ludwicki

Clinical Project Manager
Jennifer Meyering, RN, BSN, MS, CCRN
Editors

,Margaret Eckman, Diane Labus
Copy Editors

Kimberly Bilotta (supervisor), Jane Bradford, Shana
Harrington, Lisa Stockslager, Dorothy P. Terry, Pamela
Wingrod
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Georg W. Purvis IV
Illustrator
Bot Roda

Digital Composition Services
Diane Paluba (manager), Joy Rossi Biletz, Donna S.
Morris
Associate Manufacturing Manager

Beth J. Welsh
Editorial Assistants
Karen J. Kirk, Jeri O’Shea, Linda K. Ruhf

Indexer
Barbara Hodgson
Library of Congress Cataloging-in-Publication Data

Clinical pharmacology made incredibly easy!. — 3rd ed.
p.; cm.
Includes bibliographical references and index.

1. Clinical pharmacology — Outlines, syllabi, etc.
I. Lippincott Williams & Wilkins.

, [DNLM: 1. Pharmacology, Clinical — methods —
Handbooks. 2. Drug Therapy — Handbooks. 3.
Pharmaceutical Preparations — Handbooks. QV 39
C6417 2008]
RM301.28.C556 2008
615′.1—dc22
ISBN-13: 978-0-7817-8938-7 (alk. paper)
ISBN-10: 0-7817-8938-9 (alk. paper) 2008009967


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