NSG6005 Final Questions

NSG6005 Final Questions The U.S. Food and Drug Administration (FDA) regulates: The official labeling for all prescriptions and over-the-counter drugs Nurse practitioner prescriptive authority is regulated by: The State Board of Nursing for each state Electronic health records (EHRs) Allow for all patient data to be centralized in one location for access by multiple providers Alterations in drug metabolism among Asians may lead to Slower metabolism of antidepressants, requiring lower doses Pharmacokinetics among Asians are universal to all the Asian ethnic groups. B. False Gender differences between men and women in pharmacokinetics include: Higher proportion of body fat so that lipophilic drugs have relatively greater volumes of distribution The factor that has the greatest effect on males developing male sexual characteristics is: Androgen production An advantage of prescribing a sublingual medication is that the medication is: A. Absorbed rapidly Infants and young children are at higher risk of ADRs due to: B. Lack of safety and efficacy studies in the pediatric population Pharmacokinetic factors that affect prescribing include: C. Bioavailability Carbamazepine has a Black Box warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to: C. Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele Genetic polymorphisms account for differences in metabolism, including: D. All of the above A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is a(n): A. Cytotoxic hypersensitivity reaction The elderly are at high risk of ADRs due to: D. Age-related decrease in renal function The time required for the amount of drug in the body to decrease by 50% is called: Half-life The angiotensin converting enzyme (ACE) inhibitor lisinopril is a known teratogen. Teratogens cause Type ____ ADR D Common OTC pain relievers such as acetaminophen or ibuprofen: Are harmful if taken in higher than recommended amounts A patient’s nutritional intake and lab work reflect hypoalbuminemia. This is critical to prescribing because: Distribution of drugs to target tissue may be affected Warfarin resistance may be seen in patients with VCORC1 mutation, leading to: Decreased response to warfarin The first step in the prescribing process according to the World Health Organization is: C. Diagnosing the patient’s problem A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old because: A six-year-old may have problems swallowing a pill The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the: C Onset of Action When obtaining a drug history from Harold, he gives you a complete list of his prescription medications. He denies taking any other drugs, but you find that he occasionally takes aspirin for his arthritis flare-ups. This is an example of A common misconception that intermittently taken OTC medications are not an important part of his drug history Which one of the following statements about bioavailability is true? *Bioavailability issues are especially important for drugs with narrow therapeutic ranges or sustained release mechanisms All brands of a drug have the same bioavailability Drugs that are administered more than once a day have a greater bioavailability than drugs given once daily Combining an active drug with an inert substance does not affect bioavailability Beta blockers treat hypertension because they: Reduce peripheral resistance Which of the following is true about procainamide and its dosing schedule? Doses of this drug should be taken evenly spaced around the clock to keep an even blood level. Dulcea has type II diabetes and a high triglyceride level. She has gemfibrozil prescribed to treat her hypertriglyceridemia. A history of which of the following might contraindicate the use of this drug? Gallbladder disease Patients who have angina, regardless of Class who are also diabetic should be on ? ACE Inhibitors Donald has been diagnosed with hyperlipidemia. On the basis of his lipid profile, atorvastatin is prescribed. Rhabdomyolysis is a rare but serious adverse response to this drug. Donald should be told to: Report muscle weakness or tenderness and dark urine to his provider immediately