HSC 201 Pharmacology Exit HESI

The nurse should observe most closely for drug toxicity when a client receives a medication that has which characteristic?  Low bioavailability  Rapid onset of action  Short half life  Narrow therapeutic index.  Rationale: A drug with a narrow therapeutic index has a high risk for toxicity because there is a narrow range between the therapeutic dose and the toxic dose. Nurse is conducting DC teaching about anti-anxiety drug diazepam (valium) Evaluate the ingredients of all over-the-counter drugs for alcohol content Nursing instruction most important for patient on Zyloprim Increase fluid intake Client getting Tofranil (Imipramine) Give medication at night Magnesium antidote Calcium gluconate Patient with hyperthyroidism taking inderal (propanalol