PHARMACOLOGY ATI EXAM (2021) STUDY GUIDE UPDATED DOCS

PHARMACOLOGY ATI EXAM (2021) STUDY GUIDE UPDATED DOCS Chapter 1: Pharmacokinetics and Routes of Administration  Absorption – how quickly or how well it is absorbed; DEPENDS ON THE ROUTE o Oral – takes a while, must pass through the GI tract  Food can SLOW this down  pH juices play a role  Liquids vs extended release tablets o Sublingual – quick, under the tongue o Intradermal/topical – slow, gradual o Intravenous (IV) – the FASTEST route; immediate absorption  Distribution – requires binding proteins of medication o Albumin is a common binding protein  Metabolism – medication is inactivated o Occurs primarily in the LIVER o Factors that Influence Metabolism:  Age – dysfunction of liver  Children – metabolism is not mature yet..............