NR 508 WEEK 4 MIDTERM EXAM VERSION 2
COMPREHENSIVE TEST 2026 QUESTIONS AND
ANSWERS
◉ Azithromycin dosing requires that the first day's dosage be twice
those of the other 4 days of the prescription. This is considered a
loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four or five half lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues.
Answer: 1. Rapidly achieves drug levels in the therapeutic range
◉ The point in time on the drug concentration curve that indicates
the first sign of a
therapeutic effect is the:
,1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range. Answer: 3. Onset of action
◉ A laboratory result indicates that the peak level for a drug is
above the minimum toxic concentration. This means that the:
1. Concentration will produce therapeutic effects
2. Concentration will produce an adverse response
3. Time between doses must be shortened
4. Duration of action of the drug is too long. Answer: 2.
Concentration will produce an adverse response
◉ Drugs that are receptor agonists may demonstrate what property?
,1. Irreversible binding to the drug receptor site
2. Up-regulation with chronic use
3. Desensitization or down-regulation with continuous use
4. Inverse relationship between drug concentration and drug action.
Answer: 3. Desensitization or down-regulation with continuous use
◉ Drugs that are receptor antagonists, such as beta blockers, may
cause:
1. Down regulation of the drug receptor
2. And exaggerated response if abruptly discontinued
3. Partial blockade of the effects of agonist drugs
4. An exaggerated response to competitive drug agonsits. Answer: 2.
An exaggerated response if abruptly discontinued
◉ Factors that affect gastric drug absorption include
, 1. Liver enzyme activity
2. Protein-binding properties of the drug molecule
3. Lipid solubility of the drug
4. Ability to chew and swallow. Answer: 3. Lipid solubility of the
drug
◉ Drugs administered via IV;
1. Need to be lipid soluble in order to be easily absorbed
2. Begin distribution into the body immediately
3. Are easily absorbed if they are non ionized
4. May use pinocytosis to be absorbed. Answer: 2. Begin distribution
into the body immediiately
COMPREHENSIVE TEST 2026 QUESTIONS AND
ANSWERS
◉ Azithromycin dosing requires that the first day's dosage be twice
those of the other 4 days of the prescription. This is considered a
loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four or five half lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues.
Answer: 1. Rapidly achieves drug levels in the therapeutic range
◉ The point in time on the drug concentration curve that indicates
the first sign of a
therapeutic effect is the:
,1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range. Answer: 3. Onset of action
◉ A laboratory result indicates that the peak level for a drug is
above the minimum toxic concentration. This means that the:
1. Concentration will produce therapeutic effects
2. Concentration will produce an adverse response
3. Time between doses must be shortened
4. Duration of action of the drug is too long. Answer: 2.
Concentration will produce an adverse response
◉ Drugs that are receptor agonists may demonstrate what property?
,1. Irreversible binding to the drug receptor site
2. Up-regulation with chronic use
3. Desensitization or down-regulation with continuous use
4. Inverse relationship between drug concentration and drug action.
Answer: 3. Desensitization or down-regulation with continuous use
◉ Drugs that are receptor antagonists, such as beta blockers, may
cause:
1. Down regulation of the drug receptor
2. And exaggerated response if abruptly discontinued
3. Partial blockade of the effects of agonist drugs
4. An exaggerated response to competitive drug agonsits. Answer: 2.
An exaggerated response if abruptly discontinued
◉ Factors that affect gastric drug absorption include
, 1. Liver enzyme activity
2. Protein-binding properties of the drug molecule
3. Lipid solubility of the drug
4. Ability to chew and swallow. Answer: 3. Lipid solubility of the
drug
◉ Drugs administered via IV;
1. Need to be lipid soluble in order to be easily absorbed
2. Begin distribution into the body immediately
3. Are easily absorbed if they are non ionized
4. May use pinocytosis to be absorbed. Answer: 2. Begin distribution
into the body immediiately
