NUR 325 EXAM 1 ASU UPDATED WITH MOST TESTED
QUESTIONS AND ANSWERS | GRADED A+ | ASSURED SUCCESS
WITH DETAILED RATIONALES
1. Which of the following statements correctly differentiates a generic drug from a brand-
name drug?
A. A generic name is capitalized and more expensive than the brand name. B. A generic name is
not capitalized and is less expensive than the brand name. C. A brand name is always cheaper
than the generic name. D. There is no difference between generic and brand names.
Answer: B. A generic name is not capitalized and is less expensive than the brand name.
Rationale: Generic drugs are chemically identical to brand-name drugs but are marketed under
their chemical name and are typically less expensive.
2. Which of the following forms of oral medication is absorbed the fastest into the
bloodstream?
A. Tablet B. Capsule C. Powder D. Liquid
Answer: D. Liquid Rationale: Liquids do not require disintegration and dissolve more quickly,
allowing faster absorption compared to solid forms.
3. Which oral medication form absorbs the slowest due to its design to resist stomach acid?
A. Capsule B. Powder C. Enteric-coated tablet D. Liquid
Answer: C. Enteric-coated tablet Rationale: Enteric-coated tablets are designed to resist
dissolution in the stomach to prevent irritation or drug degradation; they dissolve in the
intestines, delaying absorption.
4. Which of the following routes of parenteral drug administration delivers the medication
the fastest?
A. Subcutaneous injection B. Intramuscular injection C. Intravenous injection D. Oral
administration
,ESTUDYR
Answer: C. Intravenous injection Rationale: IV administration delivers the drug directly into
the bloodstream, bypassing absorption barriers and producing an immediate effect.
5. Pharmacokinetics is best defined as:
A. The study of drug safety and regulations B. Movement of drugs from the site of
administration to various tissues C. Psychological effects of medication on patients D. The
process of writing prescriptions
Answer: B. Movement of drugs from the site of administration to various tissues Rationale:
Pharmacokinetics describes how the body absorbs, distributes, metabolizes, and excretes drugs.
6. The first-pass effect refers to:
A. The immediate distribution of a drug throughout the body after IV injection B. Partial
deactivation of some oral drugs when metabolized in the liver before reaching systemic
circulation C. Absorption of medication through the lungs D. Direct entry of medication into
circulation bypassing metabolism
Answer: B. Partial deactivation of some oral drugs when metabolized in the liver before
reaching systemic circulation Rationale: The first-pass effect reduces the bioavailability of
some oral medications, requiring higher doses compared to parenteral administration.
7. Which factor primarily influences the distribution of a drug to different body tissues?
A. Patient's favorite diet B. Circulatory system and tissue perfusion C. The time of day
medication is administered D. Environmental temperature
Answer: B. Circulatory system and tissue perfusion Rationale: Organs with rich blood
supply (liver, heart, kidneys) receive more drug, while areas with natural barriers (brain, bones)
receive less.
8. Where does drug metabolism primarily occur in the body?
A. Kidneys B. Heart C. Liver D. Lungs
Answer: C. Liver Rationale: The liver biochemically alters drugs through metabolism to
facilitate excretion and modify pharmacologic activity.
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9. The half-life of a drug refers to:
A. The time it takes for a drug to begin exerting effects B. The time it takes for half of the drug
dose to be eliminated from the body C. The maximum concentration of the drug in the
bloodstream D. The duration of therapeutic effect
Answer: B. The time it takes for half of the drug dose to be eliminated from the body
Rationale: Half-life helps determine dosing intervals and duration of therapy.
10. Peak and trough levels are measured for which primary reason?
A. To determine patient satisfaction with the drug B. To maintain therapeutic drug levels and
avoid toxicity C. To measure drug cost-effectiveness D. To assess nursing performance
Answer: B. To maintain therapeutic drug levels and avoid toxicity Rationale: Monitoring
ensures drug concentrations remain effective without causing harm.
11. Pharmacodynamics is defined as:
A. The study of how drugs move through the body B. Biochemical and physiologic effects of
drugs on the body C. Legal regulations for drug administration D. Nursing interventions to
improve drug absorption
Answer: B. Biochemical and physiologic effects of drugs on the body Rationale:
Pharmacodynamics focuses on the drug’s mechanism of action and clinical effects.
12. The most severe adverse drug reaction is:
A. Nausea B. Rash C. Anaphylactic shock D. Headache
Answer: C. Anaphylactic shock Rationale: Anaphylaxis is life-threatening and requires
immediate intervention to prevent cardiovascular collapse and death.