Simulatea reaction indirectly Stimulat
order of read
> suggested one
meta
_
,
Y .
3
glucato Cape glyceraldehyde 3-phosphate GAP)
24
Steps I-5 tructose-1 6-diphosphate <2
· ,
:
chi
,
·
>
c pyruvate
Steps 6-10 : x2 GAP
mont
Nad
+
Nash zado *
cytosolic
·
a
5
2 NAD" 2ADO 20
+
- A glucose + + + - -
pyruvate + 2 NADH + 2Ato + 2 +
·
prosthetic Lipoamite
I
Step 1 : hexokinase FAD B2
ATO
ADO + 1 +
Coenzyme A (COA) B ·
transfers acetyl to
lipayllysine 1st so it can
-Furthe
Coenzyme
u
+
NAD pick up sulfur high energy thioester band
B3
>
-
insulin-Blucokinea small
largedomain
1WATsentgenreNANAthatAlline
pyruvate
+
glucagon
Mgt find
feedforward) alaninessimirrias
↳attacks y phosphate ATP large domaina
:
+
acce
·
F- 1 , 6-BP /AMP) find PDP
PFK 1 -
Pfk 2 - ·
, allosterically
AMP ADP F-2 , 6-BP find
allosterically insulin-phosphatases dephosphorylate ATP pyruvate alanine find allosterically
3
· + , ,
, ,
samemechanis
a
ATP citrate find glucagon- Kinases-phosphorylate
>
allosterically
· ·
,
ec
~
-
2 .
amphiboliz = anabolic + catabolic Per cycle : = memorize structure
.
At
synthesis 3NADFA
3 NADH
Fatty
acid synthesis IFAD G
-
>
- late)
oysist
GGP
Petycot
use
c
3 -
.
On of c , attacks O of Ser
I
.
phosphoglucomutase
·intermetia b c goresist /Asp)
UC
~
7 GIP energy coupling)
6C
phosphorylates
Goog
·
C, in
up .
location
bond
glycosidic
UDulase
YAA
·
GD-p-V +
pp ; 5 = 0
·
releases synthesis
~
[PP > 24 :
°
1 G = -19kJ/M
neurotransmitter
Ibrain)
UDP-G ↳ Heme
synthesis
zionse ↓
ine
.
·
OH of Cy attacks G of UDP-G
·
Gadded to ends of glycogen
man-reducing
glycogen + UDP
& cells in
> pancreas >
-
glucagon mancing tap to +
pituitar
E adrenal cortex CRT
Succinate + FAD - > fumarate + FADH2
(G(u)
Hypothalamus Canterior >
-
SC
membrane
· oxidative phosphorylation :
a
~ adrenal medulla - >
epinephrine
·
cem
autonomic nervous
system
>
norepinephrine
4C
B1 , 2 ,
3 ,
5
,
6 ,7 ,
9 ,
12
P18 & Water ratios
·metomet
xitation
, gluconeogenesis -
·
B6 : nucleotide synthesis
↑Tintsenne
9 , 12
,
P10 exceptions
-B3S:fatty
acid metalsi s
Shuttle /faster)
·
glycerophosphate
n See
Inhibitors Complex ATP synthase
Rotenone Complex v
amytal
e-flow
from Itocol
·
,
Proton motive force drives Ht back into matrix viaa
Fo
↓
With
Antimycin A
ATP finds
synthase :
a se
cyanidelazie
IV
↳
also called po ratio because for everyo 2 .
F YHt (and He)
Uncouplers , used up to make H20 2 S . H2O/FADH2
FA activation
Fat mobilization ZAD
AT
synthese Late Boxidation Each round of Boxidation 1 .
Acyl dehydrogenase produces FADM
extra
adenylat CoA cannot IM (oo large)
docr-Go-store
Coinephrine-glucagon bind Acy) uses 1 H25 I COA double bond
·
cross ·
, to create
(B-OH)
triacyocerlisa
phosphorylates/activates 2 .
Hydratase adds 420 to double dond
2
- .
3 Dehydrogenase produces NADH
glycera-FAs
/glucoseAt
+ albumin
TAG . Thiolase
4
-
uses CoA to release acetyl CoA
↓ >
acyl
GNG produces I NADH
,
I FADH2 ,
L
acetyl CoA
carnitine
=
-
ferase acyarnitine
Carnitine
last round produces acetyl c o a s of round
TAGirt eca-cati no phosphatidate , o
FA synthesis , ACC -
·
insulin/protein phosphatases
reconn
acyl carrier protein (ACP)
fatty acid synthase (FAS) Malonyl COA >
-
malonyl-ACP-2C
: +
CO2 ...
↓ conservation reaction
Stra Kinase
.
2 Retox NADPH, AMP-activated protein
rxn using
Each cycle uses :
on
3 Dehydrationaeren
· 2 NADPH
using NADOL ↑
H
>
repeat wh
-
another
malonyl COA
# of
cycles = -1 NADPH +
02
Gluconeogenesis
-
·
-
chylomicrons :
dietary TAGs + cholesteral from S1-tissues ; Apoprotein 48
inmetoprote is &D
Y SI
HDL
-
:
cholesterol CEs from tissues liver ; LCAT
enzyme
I
+ >
-
GP
·
dietary liver cholestera
am
1
↑ cholestera uptake aldolase
S mevalonate (intermediate Uses : 2 glycerol + 2ATP + INAD" +
2H20
+
Produces : 1 glucose + CADD + 29 ; + INADH + 24
pyruvatena
-
L
to
genetic) h
-
↓ = I -
↑ ↑
&
9 i I
-
YTS
* Free Palestine
order of read
> suggested one
meta
_
,
Y .
3
glucato Cape glyceraldehyde 3-phosphate GAP)
24
Steps I-5 tructose-1 6-diphosphate <2
· ,
:
chi
,
·
>
c pyruvate
Steps 6-10 : x2 GAP
mont
Nad
+
Nash zado *
cytosolic
·
a
5
2 NAD" 2ADO 20
+
- A glucose + + + - -
pyruvate + 2 NADH + 2Ato + 2 +
·
prosthetic Lipoamite
I
Step 1 : hexokinase FAD B2
ATO
ADO + 1 +
Coenzyme A (COA) B ·
transfers acetyl to
lipayllysine 1st so it can
-Furthe
Coenzyme
u
+
NAD pick up sulfur high energy thioester band
B3
>
-
insulin-Blucokinea small
largedomain
1WATsentgenreNANAthatAlline
pyruvate
+
glucagon
Mgt find
feedforward) alaninessimirrias
↳attacks y phosphate ATP large domaina
:
+
acce
·
F- 1 , 6-BP /AMP) find PDP
PFK 1 -
Pfk 2 - ·
, allosterically
AMP ADP F-2 , 6-BP find
allosterically insulin-phosphatases dephosphorylate ATP pyruvate alanine find allosterically
3
· + , ,
, ,
samemechanis
a
ATP citrate find glucagon- Kinases-phosphorylate
>
allosterically
· ·
,
ec
~
-
2 .
amphiboliz = anabolic + catabolic Per cycle : = memorize structure
.
At
synthesis 3NADFA
3 NADH
Fatty
acid synthesis IFAD G
-
>
- late)
oysist
GGP
Petycot
use
c
3 -
.
On of c , attacks O of Ser
I
.
phosphoglucomutase
·intermetia b c goresist /Asp)
UC
~
7 GIP energy coupling)
6C
phosphorylates
Goog
·
C, in
up .
location
bond
glycosidic
UDulase
YAA
·
GD-p-V +
pp ; 5 = 0
·
releases synthesis
~
[PP > 24 :
°
1 G = -19kJ/M
neurotransmitter
Ibrain)
UDP-G ↳ Heme
synthesis
zionse ↓
ine
.
·
OH of Cy attacks G of UDP-G
·
Gadded to ends of glycogen
man-reducing
glycogen + UDP
& cells in
> pancreas >
-
glucagon mancing tap to +
pituitar
E adrenal cortex CRT
Succinate + FAD - > fumarate + FADH2
(G(u)
Hypothalamus Canterior >
-
SC
membrane
· oxidative phosphorylation :
a
~ adrenal medulla - >
epinephrine
·
cem
autonomic nervous
system
>
norepinephrine
4C
B1 , 2 ,
3 ,
5
,
6 ,7 ,
9 ,
12
P18 & Water ratios
·metomet
xitation
, gluconeogenesis -
·
B6 : nucleotide synthesis
↑Tintsenne
9 , 12
,
P10 exceptions
-B3S:fatty
acid metalsi s
Shuttle /faster)
·
glycerophosphate
n See
Inhibitors Complex ATP synthase
Rotenone Complex v
amytal
e-flow
from Itocol
·
,
Proton motive force drives Ht back into matrix viaa
Fo
↓
With
Antimycin A
ATP finds
synthase :
a se
cyanidelazie
IV
↳
also called po ratio because for everyo 2 .
F YHt (and He)
Uncouplers , used up to make H20 2 S . H2O/FADH2
FA activation
Fat mobilization ZAD
AT
synthese Late Boxidation Each round of Boxidation 1 .
Acyl dehydrogenase produces FADM
extra
adenylat CoA cannot IM (oo large)
docr-Go-store
Coinephrine-glucagon bind Acy) uses 1 H25 I COA double bond
·
cross ·
, to create
(B-OH)
triacyocerlisa
phosphorylates/activates 2 .
Hydratase adds 420 to double dond
2
- .
3 Dehydrogenase produces NADH
glycera-FAs
/glucoseAt
+ albumin
TAG . Thiolase
4
-
uses CoA to release acetyl CoA
↓ >
acyl
GNG produces I NADH
,
I FADH2 ,
L
acetyl CoA
carnitine
=
-
ferase acyarnitine
Carnitine
last round produces acetyl c o a s of round
TAGirt eca-cati no phosphatidate , o
FA synthesis , ACC -
·
insulin/protein phosphatases
reconn
acyl carrier protein (ACP)
fatty acid synthase (FAS) Malonyl COA >
-
malonyl-ACP-2C
: +
CO2 ...
↓ conservation reaction
Stra Kinase
.
2 Retox NADPH, AMP-activated protein
rxn using
Each cycle uses :
on
3 Dehydrationaeren
· 2 NADPH
using NADOL ↑
H
>
repeat wh
-
another
malonyl COA
# of
cycles = -1 NADPH +
02
Gluconeogenesis
-
·
-
chylomicrons :
dietary TAGs + cholesteral from S1-tissues ; Apoprotein 48
inmetoprote is &D
Y SI
HDL
-
:
cholesterol CEs from tissues liver ; LCAT
enzyme
I
+ >
-
GP
·
dietary liver cholestera
am
1
↑ cholestera uptake aldolase
S mevalonate (intermediate Uses : 2 glycerol + 2ATP + INAD" +
2H20
+
Produces : 1 glucose + CADD + 29 ; + INADH + 24
pyruvatena
-
L
to
genetic) h
-
↓ = I -
↑ ↑
&
9 i I
-
YTS
* Free Palestine
