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Pathophysiology Module 10– BIOL 331/ BIOL331 (Latest
2026/2027) | Verified Q&A | Portage Learning | Grade A
Performance
Each of the following are true of gout except:
Uric acid dissolves readily in synovial fluid
Which of the following would a patient likely exhibit on an initial physical exam if you
suspect they have OA? (mark all that apply)
capsular pattern, crepitus with movement
Which of the following are true regarding synostoses? (mark all that apply)
they allow no movement between them, they are joined by dense connective tissue
Blood circulates through bone by what means? (mark all that apply)
via central Haversian and Volkmann canals, an anastomosis between perforating and
nutrient arteries, diffusion through endosteal surface of the bone and the canaliculi
Which of the following drugs is most commonly prescribed to treat osteoporosis?
alendronate
Which of the following cells regulate bone growth through the secretion of growth
factors and tumor necrosis factor?
osteoblasts
Which of the following are true of articular cartilage?
Proteoglycans of the extracellular matrix resist compression forces
Polypeptide chains give form and tensile strength
Interstitial osmotic pressure and available fluid contribute to joint lubrication
In the liver, the inactive form of Vitamin D is converted to which of the following? (mark
all that apply)
25-hydroxyvitamin D3
Which of the following medications is used to maintain normal levels of uric acid? (mark
all that apply)
allopurinol
Damage to the synovial membrane resulting in non-specific inflammation occurs in
which stage of OA?
, late stages
Which of the following is true regarding the synovium?
The synovium secretes fluid that facilitates movement between articulating surfaces
Premature Osteoporosis is characterized by which of the following? (mark all that apply)
often a result of chronic corticosteroid use,
premature birth
T/F - If False, change the statement to make it True
Osteoblast replication and activity are increased with age.
False, Osteoblast replication and activity are decreased with age.
T/F - if False, change the statement to make it True
Haversian canals contain the nerve and blood supply for the osteon.
true
T/F - if False, change the statement to make it True
Secondary gout is characterized by the overproduction or the underexcretion of uric
acid.
False, Primary gout is characterized by the overproduction or the underexcretion of uric
acid.
T/F - if False, change the statement to make it True
Prolonged immobilization can lead to structural joint changes associated with OA.
true
If someone loses their balance when walking on uneven terrain, explain how tendons
and ligaments work to protect the joint and structures within it.
The tendons and ligaments of joints serve in proprioception (the awareness of ones'
position in space or movement of the body). When these structures undergo stretch or
torsional strain, these proprioceptive nerve fibers will cause a reflexive response to
adjust the tension on the muscles (to maintain balance and not fall over) that support
the joint protecting the capsule and other joint structures.
A patient presents to the ER with severe pain in their right ankle. Blood tests reveal
serum uric acid levels of 7.8 mg/dL. They are kept for observation and their 24-hr urine
specimen reveals underexcretion of urate. Which phase of gout are they in? What is the
goal of your treatment given the phase they are in?
This patient is in phase 2 of gout or acute gout arthritis. The goal of treatment is to
manage symptoms and terminate the acute attack primarily through NSAIDS.
Give 2 reasons that males are at a decreased risk for developing osteoporosis than
females.
Males achieve 8-10% greater peak BMD than females do; they do not go through a
midlife decline of sex hormone production.
Pathophysiology Module 10– BIOL 331/ BIOL331 (Latest
2026/2027) | Verified Q&A | Portage Learning | Grade A
Performance
Each of the following are true of gout except:
Uric acid dissolves readily in synovial fluid
Which of the following would a patient likely exhibit on an initial physical exam if you
suspect they have OA? (mark all that apply)
capsular pattern, crepitus with movement
Which of the following are true regarding synostoses? (mark all that apply)
they allow no movement between them, they are joined by dense connective tissue
Blood circulates through bone by what means? (mark all that apply)
via central Haversian and Volkmann canals, an anastomosis between perforating and
nutrient arteries, diffusion through endosteal surface of the bone and the canaliculi
Which of the following drugs is most commonly prescribed to treat osteoporosis?
alendronate
Which of the following cells regulate bone growth through the secretion of growth
factors and tumor necrosis factor?
osteoblasts
Which of the following are true of articular cartilage?
Proteoglycans of the extracellular matrix resist compression forces
Polypeptide chains give form and tensile strength
Interstitial osmotic pressure and available fluid contribute to joint lubrication
In the liver, the inactive form of Vitamin D is converted to which of the following? (mark
all that apply)
25-hydroxyvitamin D3
Which of the following medications is used to maintain normal levels of uric acid? (mark
all that apply)
allopurinol
Damage to the synovial membrane resulting in non-specific inflammation occurs in
which stage of OA?
, late stages
Which of the following is true regarding the synovium?
The synovium secretes fluid that facilitates movement between articulating surfaces
Premature Osteoporosis is characterized by which of the following? (mark all that apply)
often a result of chronic corticosteroid use,
premature birth
T/F - If False, change the statement to make it True
Osteoblast replication and activity are increased with age.
False, Osteoblast replication and activity are decreased with age.
T/F - if False, change the statement to make it True
Haversian canals contain the nerve and blood supply for the osteon.
true
T/F - if False, change the statement to make it True
Secondary gout is characterized by the overproduction or the underexcretion of uric
acid.
False, Primary gout is characterized by the overproduction or the underexcretion of uric
acid.
T/F - if False, change the statement to make it True
Prolonged immobilization can lead to structural joint changes associated with OA.
true
If someone loses their balance when walking on uneven terrain, explain how tendons
and ligaments work to protect the joint and structures within it.
The tendons and ligaments of joints serve in proprioception (the awareness of ones'
position in space or movement of the body). When these structures undergo stretch or
torsional strain, these proprioceptive nerve fibers will cause a reflexive response to
adjust the tension on the muscles (to maintain balance and not fall over) that support
the joint protecting the capsule and other joint structures.
A patient presents to the ER with severe pain in their right ankle. Blood tests reveal
serum uric acid levels of 7.8 mg/dL. They are kept for observation and their 24-hr urine
specimen reveals underexcretion of urate. Which phase of gout are they in? What is the
goal of your treatment given the phase they are in?
This patient is in phase 2 of gout or acute gout arthritis. The goal of treatment is to
manage symptoms and terminate the acute attack primarily through NSAIDS.
Give 2 reasons that males are at a decreased risk for developing osteoporosis than
females.
Males achieve 8-10% greater peak BMD than females do; they do not go through a
midlife decline of sex hormone production.
