ABSITE TrueLearn-Style Practice Exam 2026 | High-Yield
General Surgery Questions with Verified Answers | Updated
ABSITE Board Review
The ABSITE TrueLearn-Style Practice Exam 2026 is a high-yield surgical review resource
designed for general surgery residents preparing for the American Board of Surgery In-
Training Examination (ABSITE). This practice exam mirrors the TrueLearn question style,
difficulty level, and clinical reasoning required for success on the ABSITE.
The question set emphasizes frequently tested and high-scoring ABSITE topics, including
clinical decision-making, operative management, perioperative care, surgical nutrition,
trauma, critical care, gastrointestinal surgery, hepatobiliary disease, endocrine surgery,
and surgical pathology. Each question includes verified correct answers to reinforce key
concepts and promote rapid exam readiness.
Updated for ABSITE 2026, this resource is ideal for daily question practice, targeted
remediation, and final review, helping residents strengthen weak areas and improve overall
exam performance.
• ABSITE TrueLearn practice exam
• ABSITE practice questions 2026
• General surgery ABSITE review
• TrueLearn style ABSITE questions
Pharmacokinetics Right Ans - how the organism affects the drug
can intestinalis pneumotosis be caused by pulmonary disease? Right Ans -
yes, rule out intestinal catastrophe first
Blind loop syndrome Right Ans - caused by bacterial overgrowth, leads to
fat malabsorption, steatorrhea and vit deficiency, can occur with crohns
,When to use fistulotomy Right Ans - If < 20% sphincter involved
cutting seton vs draining seton Right Ans - use cutting if > 20 % of
sphincter is involved ,use draining if purulent
second degree frostbite Right Ans - milky white blisters, aspirate to
prevent prostaglandin formation
hemorrhagic frostbite blisters Right Ans - do not aspirate
hydatid cysts most frequent organism Right Ans - echinococcus granulosus
hydatid cyst definitive host Right Ans - dogs
CEAP classification Right Ans - Clinical
Etiology
Anatomy
Pathophysiology
Lifethreatening side effect from protamine Right Ans - hypotension
What happens to non absorbed saccharides in the digestive tract? Right
Ans - Digested by intestinal bacteria to form short chain fatty acids
Very high vitamin D levels can cause what? Right Ans - increased mortality
and ACS
Monosaccharide glucose and galactose are transported by what mechanism?
Right Ans - Sodium dependent secondary transport
Monosaccharide fructose transported by what mechanism? Right Ans - Na
independent facilitated diffusion
Kidneys use what to perform gluconeogenesis? Right Ans - glutamine and
glutamate
, Most common etiology for ESRD requiring transplant? Right Ans - DM then
HTN
Vitamin deficiency 4-6 weeks after bariatric surgery with peripheral
neuropathy? Right Ans - Vit B1, thiamine. peripheral neuropathy
Recommended protein intake per day? Right Ans - 0.8 g/kg/day
Daily nitrogen requirement Right Ans - protein/6.25
Can you do bolus feeds through J tube? Right Ans - No, only gastric
Primary fuel of large bowel Right Ans - short chain fatty acids
Magnesium toxicity Right Ans - confusion, loss of deep tendon reflexes,
flaccid paralysis, hypotension, respiratory failure, cardiac arrhythmia, cardiac
arrest
Copper Deficiency Right Ans - pancytopenia, neuropathy with ataxia
When can chemotherapy for breast cancer be given in pregnancy? Right
Ans - second trimester
Chylous ascites Right Ans - triglycerides > 110, most common cause in
developed world: lymphoma, most common cause in undeveloped world:
infectious
Highly selective vagotomy Right Ans - preserves Latarget's nerves
(pylorus), posterior vagus (small intestine and pancreas) and anterior vagus
(liver and gallbladder)
Sudden rise in end tidal CO2 during operation Right Ans - increase tidal
volume, most likely atelectasis. Rare but concerning cause would be malignant
hyperthermia
Congenital lobar emphysema Right Ans - Can cause severe respiratory
distress, looks like pneumothorax, Chest tube makes it worse. If severe,
requires lobectomy
General Surgery Questions with Verified Answers | Updated
ABSITE Board Review
The ABSITE TrueLearn-Style Practice Exam 2026 is a high-yield surgical review resource
designed for general surgery residents preparing for the American Board of Surgery In-
Training Examination (ABSITE). This practice exam mirrors the TrueLearn question style,
difficulty level, and clinical reasoning required for success on the ABSITE.
The question set emphasizes frequently tested and high-scoring ABSITE topics, including
clinical decision-making, operative management, perioperative care, surgical nutrition,
trauma, critical care, gastrointestinal surgery, hepatobiliary disease, endocrine surgery,
and surgical pathology. Each question includes verified correct answers to reinforce key
concepts and promote rapid exam readiness.
Updated for ABSITE 2026, this resource is ideal for daily question practice, targeted
remediation, and final review, helping residents strengthen weak areas and improve overall
exam performance.
• ABSITE TrueLearn practice exam
• ABSITE practice questions 2026
• General surgery ABSITE review
• TrueLearn style ABSITE questions
Pharmacokinetics Right Ans - how the organism affects the drug
can intestinalis pneumotosis be caused by pulmonary disease? Right Ans -
yes, rule out intestinal catastrophe first
Blind loop syndrome Right Ans - caused by bacterial overgrowth, leads to
fat malabsorption, steatorrhea and vit deficiency, can occur with crohns
,When to use fistulotomy Right Ans - If < 20% sphincter involved
cutting seton vs draining seton Right Ans - use cutting if > 20 % of
sphincter is involved ,use draining if purulent
second degree frostbite Right Ans - milky white blisters, aspirate to
prevent prostaglandin formation
hemorrhagic frostbite blisters Right Ans - do not aspirate
hydatid cysts most frequent organism Right Ans - echinococcus granulosus
hydatid cyst definitive host Right Ans - dogs
CEAP classification Right Ans - Clinical
Etiology
Anatomy
Pathophysiology
Lifethreatening side effect from protamine Right Ans - hypotension
What happens to non absorbed saccharides in the digestive tract? Right
Ans - Digested by intestinal bacteria to form short chain fatty acids
Very high vitamin D levels can cause what? Right Ans - increased mortality
and ACS
Monosaccharide glucose and galactose are transported by what mechanism?
Right Ans - Sodium dependent secondary transport
Monosaccharide fructose transported by what mechanism? Right Ans - Na
independent facilitated diffusion
Kidneys use what to perform gluconeogenesis? Right Ans - glutamine and
glutamate
, Most common etiology for ESRD requiring transplant? Right Ans - DM then
HTN
Vitamin deficiency 4-6 weeks after bariatric surgery with peripheral
neuropathy? Right Ans - Vit B1, thiamine. peripheral neuropathy
Recommended protein intake per day? Right Ans - 0.8 g/kg/day
Daily nitrogen requirement Right Ans - protein/6.25
Can you do bolus feeds through J tube? Right Ans - No, only gastric
Primary fuel of large bowel Right Ans - short chain fatty acids
Magnesium toxicity Right Ans - confusion, loss of deep tendon reflexes,
flaccid paralysis, hypotension, respiratory failure, cardiac arrhythmia, cardiac
arrest
Copper Deficiency Right Ans - pancytopenia, neuropathy with ataxia
When can chemotherapy for breast cancer be given in pregnancy? Right
Ans - second trimester
Chylous ascites Right Ans - triglycerides > 110, most common cause in
developed world: lymphoma, most common cause in undeveloped world:
infectious
Highly selective vagotomy Right Ans - preserves Latarget's nerves
(pylorus), posterior vagus (small intestine and pancreas) and anterior vagus
(liver and gallbladder)
Sudden rise in end tidal CO2 during operation Right Ans - increase tidal
volume, most likely atelectasis. Rare but concerning cause would be malignant
hyperthermia
Congenital lobar emphysema Right Ans - Can cause severe respiratory
distress, looks like pneumothorax, Chest tube makes it worse. If severe,
requires lobectomy
