Pharm II Exam 1 UAMS CON Questions and
Answers (100% Correct Answers) Already
Graded A+
autoimmune disorder; begins usually between ages 30-60;
usually affects joints symmetrically and cartialge begins
to self destruct [ Ans: ] Rheumatoid arthritis (RA)
What medication classes are used to treat RA? [ Ans: ]
DMARDS, Glucocorticoids, NSAIDS
What is the purpose of DMARDS? [ Ans: ] To slow the
progression of RA
What are the 5 prototype drugs for DMARDS I? [ Ans: ]
Hydroxychloroquine, leflunomide, methotrexate,
minocycline, and sulfasalazine
What are the 3 prototype drugs for DMARDS II? (AIE) [ Ans:
] Adalimumab, infliximab, etanercept
What are the 4 prototype drugs for DMARDS III? (APAC) [
Ans: ] Auranofin, penicillamine, azathioprine,,
cyclosporine
How long could it take for DMARDS to become
therapeutic? [ Ans: ] 3-6 weeks for any response; and
several months to be therapeutic
What is the purpose of glucocorticoids when treating RA? [
Ans: ] Reduce inflammation and pain
,What are the 2 prototypes for glucocorticoids? [ Ans: ]
Prednisone and prednisolone
What is an Intra articular injection? [ Ans: ] injection into a
joint
How can glucocorticoids be administered? [ Ans: ] PO or
intra articular
What is the purpose of NSAIDS when treating RA? [ Ans: ]
Rapidly reduce pain and inflammation
List some NSAIDS [ Ans: ] Aspirin
Ibuprofen
Diclofenac
Indomethacin
Meloxicam
Naproxen
Celecoxib
What is the main goal when treating RA? [ Ans: ] Reduce
swelling and stiffness in joints, improve ability to
maintain joint function, and reduce pain
What are the 4 major side effects of DMARDS? [ Ans: ] -
immunosuppression
, -bone marrow suppression
-skin and GI issues
-liver and renal issues
What will the nurse monitor when a patient is taking
DMARDS? And why? [ Ans: ] -CBC and labs because of bone
marrow suppression and liver and renal issues
What does the patient need to report when taking
DMARDS? [ Ans: ] Any bruising, bleeding (gums), and s/s
of illness (immunosuppression)
What is a major side effect of Hydroxychloroquine?
(DMARDS I) [ Ans: ] Retinal damage
What exam should a patient before and while taking
hydroxychloroquine? [ Ans: ] Eye exam before and every 6
months while on medicine
What medicine should not be given with cyclosporine?
(DMARD) [ Ans: ] Erythromycin; increases risk of toxicity
of cyclo
What are signs of toxicity in patients taking methotrexate
and auranofin? [ Ans: ] Mouth sores
What pregnancy category is methotrexate? [ Ans: ]
Pregnancy Category X
Answers (100% Correct Answers) Already
Graded A+
autoimmune disorder; begins usually between ages 30-60;
usually affects joints symmetrically and cartialge begins
to self destruct [ Ans: ] Rheumatoid arthritis (RA)
What medication classes are used to treat RA? [ Ans: ]
DMARDS, Glucocorticoids, NSAIDS
What is the purpose of DMARDS? [ Ans: ] To slow the
progression of RA
What are the 5 prototype drugs for DMARDS I? [ Ans: ]
Hydroxychloroquine, leflunomide, methotrexate,
minocycline, and sulfasalazine
What are the 3 prototype drugs for DMARDS II? (AIE) [ Ans:
] Adalimumab, infliximab, etanercept
What are the 4 prototype drugs for DMARDS III? (APAC) [
Ans: ] Auranofin, penicillamine, azathioprine,,
cyclosporine
How long could it take for DMARDS to become
therapeutic? [ Ans: ] 3-6 weeks for any response; and
several months to be therapeutic
What is the purpose of glucocorticoids when treating RA? [
Ans: ] Reduce inflammation and pain
,What are the 2 prototypes for glucocorticoids? [ Ans: ]
Prednisone and prednisolone
What is an Intra articular injection? [ Ans: ] injection into a
joint
How can glucocorticoids be administered? [ Ans: ] PO or
intra articular
What is the purpose of NSAIDS when treating RA? [ Ans: ]
Rapidly reduce pain and inflammation
List some NSAIDS [ Ans: ] Aspirin
Ibuprofen
Diclofenac
Indomethacin
Meloxicam
Naproxen
Celecoxib
What is the main goal when treating RA? [ Ans: ] Reduce
swelling and stiffness in joints, improve ability to
maintain joint function, and reduce pain
What are the 4 major side effects of DMARDS? [ Ans: ] -
immunosuppression
, -bone marrow suppression
-skin and GI issues
-liver and renal issues
What will the nurse monitor when a patient is taking
DMARDS? And why? [ Ans: ] -CBC and labs because of bone
marrow suppression and liver and renal issues
What does the patient need to report when taking
DMARDS? [ Ans: ] Any bruising, bleeding (gums), and s/s
of illness (immunosuppression)
What is a major side effect of Hydroxychloroquine?
(DMARDS I) [ Ans: ] Retinal damage
What exam should a patient before and while taking
hydroxychloroquine? [ Ans: ] Eye exam before and every 6
months while on medicine
What medicine should not be given with cyclosporine?
(DMARD) [ Ans: ] Erythromycin; increases risk of toxicity
of cyclo
What are signs of toxicity in patients taking methotrexate
and auranofin? [ Ans: ] Mouth sores
What pregnancy category is methotrexate? [ Ans: ]
Pregnancy Category X
