Federal MPJE Practice Questions and Answers | Latest Version | 2025/2026 | Correct & Verified

Federal MPJE Practice Questions and Answers | Latest Version | 2025/2026 | Correct & Verified What is the purpose of the federal MPJE exam? To test knowledge and application of federal pharmacy law. Which federal agency regulates controlled substances? The Drug Enforcement Administration (DEA). Which federal law sets the standard for prescription drug safety and labeling? The Federal Food, Drug, and Cosmetic Act (FDCA). What federal law regulates the practice of controlled substances in the U.S.? The Controlled Substances Act (CSA). Who must register with the DEA to handle controlled substances? Pharmacists, pharmacies, prescribers, and manufacturers. Which schedule of drugs has the highest potential for abuse with no accepted medical use? Schedule I. 2 Which schedule of drugs has a lower potential for abuse than Schedule II and accepted medical use? Schedule III. What is required for a pharmacy to dispense Schedule II drugs? A written or electronic prescription signed by a DEA-registered prescriber. Can Schedule III-V prescriptions be faxed to a pharmacy? Yes, if compliant with federal regulations. What is the federal requirement for controlled substance inventories? An initial inventory and biennial inventories thereafter. What federal form is used to order Schedule I or II substances? DEA Form 222. What is required when a pharmacy discovers a theft or significant loss of controlled substances? Report immediately to the DEA using DEA Form 106. Can pharmacists refill Schedule II prescriptions? No, refills are not allowed for Schedule II drugs. 3 How many refills are allowed for Schedule III or IV prescriptions? Up to five refills within six months of the issue date. What is required for electronic prescriptions for controlled substances? DEA-compliant electronic prescribing system. What is the purpose of a DEA number? To uniquely identify prescribers and registrants authorized to handle controlled substances. What is the purpose of a DEA Form 41? To document destruction of controlled substances. Who is responsible for monitoring controlled substance diversion in pharmacies? The pharmacist-in-charge. What is required for transfer of Schedule III-V prescriptions between pharmacies? One-time transfer with proper documentation and DEA compliance. What is the federal requirement for recordkeeping of controlled substances? Maintain accurate, complete records for at least two years. What is the role of a pharmacist in patient counseling regarding controlled substances? 4 Provide guidance on proper use, side effects, and storage. What is required before dispensing a prescription for a narcotic under federal law? Verify the prescriber is DEA-registered and the prescription is valid. Can controlled substances be dispensed without a prescription? Only under emergency situations for Schedule II with proper documentation. What federal law requires reporting of adverse drug events? FDA’s MedWatch program under the FDCA. Which form must be completed to transfer Schedule