NURS 751 FINAL EXAM (2025)
100%VERIFIED |complete QUESTIONS
AND ANSWERS | GRADED A+.
ClinicalvSignificancevofvResiliencev-vcorrect-answersv-Lowersvriskvof:
Depression
Anxiety
PTSD
ovModeratesvresponsevtovtreatment
DefinitionvofvResiliencev-vcorrect-answersv-Capacityvtoveffectivelyvcopevwithvandvrespondvtovstress
Neurobiological,vCognitivevandvBehavioralvfeaturesvofvResiliencev-vcorrect-answersv-
ovIntactvrewardvandvmotivationvsystems
ovAppropriatevfearvresponses
ovAdaptivevsocialvbehaviorsv(altruism,vsocialvbonding)
ovAccuratevthreatvappraisal
,ovAvoidsvoverlyvnegativevorvoverlyvpositivevbiases
First-linevagentvforvPTSDv-vcorrect-answersv-SSRIsvarevfirst-linevforvPTSD
ovSertralinev(Zoloft)vcarriesvanvFDAvindicationvforvPTSD
TreatmentvforvSleepvDisturbancesvassociatedvwithvPTSDv-vcorrect-answersv-
Temazepamv(benzodiazepine)vGAGBA-Avagonist.vmayvbevusedvforvshort-termvforvsleepvdisruption
•vTrazodonev(α1vantagonist)vmayvalsovhelpvwithvPTSD-relatedvinsomniav(off-label)
•vPrazosinv(minipress)v(α1vantagonist)visvespeciallyvhelpfulvforvnightmaresvinvveterans
Dosingvprotocolvforvprazosinv-vcorrect-answersv-ovStart:v1vmgvatvbedtimevforv≥3vnights
ovTitrate:v3-15vmgv(meanvdosev~10vmg)
v Improvesvsleepvlatencyvandvduration
WhatvisvusedvforvadrenergicvmodulationvinvPTSD?v-vcorrect-answersv-Propranololv(betavblocker)
WhatvtovknowvaboutvPropanololvforvPTSD?v-vcorrect-answersv-BetavBlocker
mayvpreventvPTSDvifvgivenvearly
ovCrossesvblood-brainvbarrierv→vbluntsvadrenergicvoverconsolidationvofvtrauma
memory
ovMostveffectivevifvinitiatedvwithinv6-24vhoursvofvtrauma
ovTypicalvdose:v40vmgvTIDvtovQIDvforv7-10vdays
NNT-v6-8.v(experimental)
, NNH-v50+v(bradycardia,vfatigue)
WhatvisvusedvtovtreatvhyperarousalvinvPTSD?v-vcorrect-answersv-ClonidinevandvGuanfacinev
ovAvoidvabruptvwithdrawalv→vreboundvhypertensionv(especiallyvwithvclonidine)
•vClonidine:vbindsvtovα2A,vα2B,vα2Cv→vmorevsedating
(reducesvhyperarousalvandvsympatheticvtone)
•vGuanfacine:vmorevselectivevforvα2Av→vlessvsedationv(improvesvsleepvandvemotionalvregulation)
StudyvbasedvdosingvrecommendationsvforvHydrocortisonevinvtreatingvPTSDv-vcorrect-answersv-
100vmgvhydrocortisonevIVvTIDvforv5vdaysvpost-op
100-140vmg/dayvhydrocortisonevforv10vdaysvpost-trauma
Avsinglev100vmgvIVvdosevofvhydrocortisonevadministeredvwithinv6vhoursvof
traumavwasvassociatedvwithvreducedvintrusivevmemoriesvandvlowervCAPSvscoresvatv1
month.
20-30vmgvPOvBIDvxv10vdaysvstartingvwithinv12vhoursvofvtraumavreduced
PTSDvsymptomsvandvdecreasedvemotionalvmemoryvconsolidation.
whatvtovknowvaboutvhydrocortisonevforvPTSDv-vcorrect-answersv-preventativevuse
Mechanism-HPAvaxisvmodulation;vbluntsvtraumavmemoryvconsolidation
100%VERIFIED |complete QUESTIONS
AND ANSWERS | GRADED A+.
ClinicalvSignificancevofvResiliencev-vcorrect-answersv-Lowersvriskvof:
Depression
Anxiety
PTSD
ovModeratesvresponsevtovtreatment
DefinitionvofvResiliencev-vcorrect-answersv-Capacityvtoveffectivelyvcopevwithvandvrespondvtovstress
Neurobiological,vCognitivevandvBehavioralvfeaturesvofvResiliencev-vcorrect-answersv-
ovIntactvrewardvandvmotivationvsystems
ovAppropriatevfearvresponses
ovAdaptivevsocialvbehaviorsv(altruism,vsocialvbonding)
ovAccuratevthreatvappraisal
,ovAvoidsvoverlyvnegativevorvoverlyvpositivevbiases
First-linevagentvforvPTSDv-vcorrect-answersv-SSRIsvarevfirst-linevforvPTSD
ovSertralinev(Zoloft)vcarriesvanvFDAvindicationvforvPTSD
TreatmentvforvSleepvDisturbancesvassociatedvwithvPTSDv-vcorrect-answersv-
Temazepamv(benzodiazepine)vGAGBA-Avagonist.vmayvbevusedvforvshort-termvforvsleepvdisruption
•vTrazodonev(α1vantagonist)vmayvalsovhelpvwithvPTSD-relatedvinsomniav(off-label)
•vPrazosinv(minipress)v(α1vantagonist)visvespeciallyvhelpfulvforvnightmaresvinvveterans
Dosingvprotocolvforvprazosinv-vcorrect-answersv-ovStart:v1vmgvatvbedtimevforv≥3vnights
ovTitrate:v3-15vmgv(meanvdosev~10vmg)
v Improvesvsleepvlatencyvandvduration
WhatvisvusedvforvadrenergicvmodulationvinvPTSD?v-vcorrect-answersv-Propranololv(betavblocker)
WhatvtovknowvaboutvPropanololvforvPTSD?v-vcorrect-answersv-BetavBlocker
mayvpreventvPTSDvifvgivenvearly
ovCrossesvblood-brainvbarrierv→vbluntsvadrenergicvoverconsolidationvofvtrauma
memory
ovMostveffectivevifvinitiatedvwithinv6-24vhoursvofvtrauma
ovTypicalvdose:v40vmgvTIDvtovQIDvforv7-10vdays
NNT-v6-8.v(experimental)
, NNH-v50+v(bradycardia,vfatigue)
WhatvisvusedvtovtreatvhyperarousalvinvPTSD?v-vcorrect-answersv-ClonidinevandvGuanfacinev
ovAvoidvabruptvwithdrawalv→vreboundvhypertensionv(especiallyvwithvclonidine)
•vClonidine:vbindsvtovα2A,vα2B,vα2Cv→vmorevsedating
(reducesvhyperarousalvandvsympatheticvtone)
•vGuanfacine:vmorevselectivevforvα2Av→vlessvsedationv(improvesvsleepvandvemotionalvregulation)
StudyvbasedvdosingvrecommendationsvforvHydrocortisonevinvtreatingvPTSDv-vcorrect-answersv-
100vmgvhydrocortisonevIVvTIDvforv5vdaysvpost-op
100-140vmg/dayvhydrocortisonevforv10vdaysvpost-trauma
Avsinglev100vmgvIVvdosevofvhydrocortisonevadministeredvwithinv6vhoursvof
traumavwasvassociatedvwithvreducedvintrusivevmemoriesvandvlowervCAPSvscoresvatv1
month.
20-30vmgvPOvBIDvxv10vdaysvstartingvwithinv12vhoursvofvtraumavreduced
PTSDvsymptomsvandvdecreasedvemotionalvmemoryvconsolidation.
whatvtovknowvaboutvhydrocortisonevforvPTSDv-vcorrect-answersv-preventativevuse
Mechanism-HPAvaxisvmodulation;vbluntsvtraumavmemoryvconsolidation
