ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE LATEST
UPDATE ACTUAL EXAM QUESTIONS
DefineLneoadjuvantLtherapyL-
LCORRECTLANSWERSTreatmentLisLgivenLpriorLtoLsurgeryLtoLshrinkLtheLtumor
DefineLadjuvantLtherapyL-
LCORRECTLANSWERSAdditionalLcancerLtreatmentLgivenLafterLtheLprimaryLtreatmentLtoLlowerLtheLri
skLthatLtheLcancerLreoccur
3LsubcategoriesLofLalkylatingLagents:L-LCORRECTLANSWERS1.LNitrogenLmustards
2.LPlatinum-
basedLagentsL(doLnotLpossessLanLalkylLgroupLbutLstillLtermedLalkylatingLagentsLasLtheyLworkLsimilarl
y)
3.LNitrosoureas
CommonLalkylatingLagents:L-LCORRECTLANSWERSCyclophosphamideL(Cytoxan)
IfosfamideL(Ifex)
BendamustineL(Treanda)
CommonLplatinum-basedLagents:L-LCORRECTLANSWERSCisplatinL(Platinol)
CarboplatinL(Paraplatin)
WhatLisLuniqueLaboutLnitrosoureasLagents?L-LCORRECTLANSWERSAbleLtoLcrossLtheLblood-
brainLbarrier;LcanLbeLeffectiveLinLtreatingLsomeLbrainLtumors
CommonLnitrosoureasLagents:L-LCORRECTLANSWERSCarmustineL(BiCNU)
LomustineL(CeeNu)
,StreptozocinL(Zanosar)
HypersensitivityLcanLoccurLwithLlateLdosesLof:L-LCORRECTLANSWERSCarboplatin
TheseLagentsLareLtypicallyLcategorizedLasLhighlyLemetogenic:L-
LCORRECTLANSWERS1.LAlkylatingLagents
2.LNitrosoureas
Pre-administrationLlabsLforLalkylatingLagentsLandLnitrosoureas:L-LCORRECTLANSWERSBUN
Creatinine
CBCLw/Ldiff
WhatLisLtheLmedicationLMesnaLusedLfor?L-
LCORRECTLANSWERSBladderLprotectantLwithLadministrationLofLcyclophosphamideLorLifosfamide
InstructLptsLreceivingL________LtoLavoidLexposureLtoLcoldLairLandLconsumingLcoldLfluidsLforL3-
4LdaysLfollowingLtreatmentL-LCORRECTLANSWERSOxaliplatin
HowLdoLantimetabolitesLfunction?L-
LCORRECTLANSWERSByLblockingLDNALandLRNALgrowthLbyLinterferingLwithLenzymesLneededLforLnor
malLcellLmetabolism
AntimetabolitesLworkLinLtheL___Lphase.L-LCORRECTLANSWERSS
CommonLsideLeffectsLofLantimetabolites:L-LCORRECTLANSWERSMyelosuppression
GILtoxicities
Photosensitivity
, Hand-footLsyndrome
CommonLantimetaboliteLdrugs:L-LCORRECTLANSWERSAzacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
TheLinstituteLforLSafeLMedicationLPracticesLrecommendsLwhatLrouteLofLadministrationLforLvincristi
ne?L-LCORRECTLANSWERSIVLpiggybackLviaLgravity
AnthracyclineLantitumorLabxLworkLby:L-
LCORRECTLANSWERSInterferingLwithLenzymesLnecessaryLforLDNALtoLreplicateLinLALLLphasesLofLtheL
cellLcycle
TheLtwoLmajorLclassificationsLofLantitumorLantibioticsLare:L-LCORRECTLANSWERSAnthracyclines
Non-anthracyclines
CommonLanthracyclineLantitumorLabx:L-LCORRECTLANSWERSDaunorubicin
Doxorubicin
Epirubicin
Idarubicin
TheLantitumorLabxL___________LisLnotLanLanthracycline,LbutLhasLanthracycline-typeLproperties.L-
LCORRECTLANSWERSMitoxantrone
UPDATE ACTUAL EXAM QUESTIONS
DefineLneoadjuvantLtherapyL-
LCORRECTLANSWERSTreatmentLisLgivenLpriorLtoLsurgeryLtoLshrinkLtheLtumor
DefineLadjuvantLtherapyL-
LCORRECTLANSWERSAdditionalLcancerLtreatmentLgivenLafterLtheLprimaryLtreatmentLtoLlowerLtheLri
skLthatLtheLcancerLreoccur
3LsubcategoriesLofLalkylatingLagents:L-LCORRECTLANSWERS1.LNitrogenLmustards
2.LPlatinum-
basedLagentsL(doLnotLpossessLanLalkylLgroupLbutLstillLtermedLalkylatingLagentsLasLtheyLworkLsimilarl
y)
3.LNitrosoureas
CommonLalkylatingLagents:L-LCORRECTLANSWERSCyclophosphamideL(Cytoxan)
IfosfamideL(Ifex)
BendamustineL(Treanda)
CommonLplatinum-basedLagents:L-LCORRECTLANSWERSCisplatinL(Platinol)
CarboplatinL(Paraplatin)
WhatLisLuniqueLaboutLnitrosoureasLagents?L-LCORRECTLANSWERSAbleLtoLcrossLtheLblood-
brainLbarrier;LcanLbeLeffectiveLinLtreatingLsomeLbrainLtumors
CommonLnitrosoureasLagents:L-LCORRECTLANSWERSCarmustineL(BiCNU)
LomustineL(CeeNu)
,StreptozocinL(Zanosar)
HypersensitivityLcanLoccurLwithLlateLdosesLof:L-LCORRECTLANSWERSCarboplatin
TheseLagentsLareLtypicallyLcategorizedLasLhighlyLemetogenic:L-
LCORRECTLANSWERS1.LAlkylatingLagents
2.LNitrosoureas
Pre-administrationLlabsLforLalkylatingLagentsLandLnitrosoureas:L-LCORRECTLANSWERSBUN
Creatinine
CBCLw/Ldiff
WhatLisLtheLmedicationLMesnaLusedLfor?L-
LCORRECTLANSWERSBladderLprotectantLwithLadministrationLofLcyclophosphamideLorLifosfamide
InstructLptsLreceivingL________LtoLavoidLexposureLtoLcoldLairLandLconsumingLcoldLfluidsLforL3-
4LdaysLfollowingLtreatmentL-LCORRECTLANSWERSOxaliplatin
HowLdoLantimetabolitesLfunction?L-
LCORRECTLANSWERSByLblockingLDNALandLRNALgrowthLbyLinterferingLwithLenzymesLneededLforLnor
malLcellLmetabolism
AntimetabolitesLworkLinLtheL___Lphase.L-LCORRECTLANSWERSS
CommonLsideLeffectsLofLantimetabolites:L-LCORRECTLANSWERSMyelosuppression
GILtoxicities
Photosensitivity
, Hand-footLsyndrome
CommonLantimetaboliteLdrugs:L-LCORRECTLANSWERSAzacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
TheLinstituteLforLSafeLMedicationLPracticesLrecommendsLwhatLrouteLofLadministrationLforLvincristi
ne?L-LCORRECTLANSWERSIVLpiggybackLviaLgravity
AnthracyclineLantitumorLabxLworkLby:L-
LCORRECTLANSWERSInterferingLwithLenzymesLnecessaryLforLDNALtoLreplicateLinLALLLphasesLofLtheL
cellLcycle
TheLtwoLmajorLclassificationsLofLantitumorLantibioticsLare:L-LCORRECTLANSWERSAnthracyclines
Non-anthracyclines
CommonLanthracyclineLantitumorLabx:L-LCORRECTLANSWERSDaunorubicin
Doxorubicin
Epirubicin
Idarubicin
TheLantitumorLabxL___________LisLnotLanLanthracycline,LbutLhasLanthracycline-typeLproperties.L-
LCORRECTLANSWERSMitoxantrone
