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CARN-AP Exam Review (2025/2026) | 250+ Questions & Answers | Addictions Nursing, MAT, Withdrawal, Substance Use

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This in-depth study guide is designed for candidates preparing for the Certified Addiction Registered Nurse - Advanced Practice (CARN-AP) exam for the 2025/2026 cycle. The document includes over 250 exam-style questions and fully explained answers, based on the most current clinical practices and diagnostic frameworks. Topics span across substance use disorders (SUD), alcohol use disorder (AUD), opioid use disorder (OUD), medication-assisted treatment (MAT) options (e.g., naltrexone, disulfiram, buprenorphine), withdrawal syndromes, intoxication profiles, DSM-5 criteria, neurobiology, screening tools (e.g., AUDIT, CAGE, CRAFFT), and management of psychiatric comorbidities. The format promotes active recall and test readiness, making it ideal for students, nurse practitioners, and advanced practice clinicians in training. Whether you're in a PMHNP, FNP, AGNP, DNP, or MSN program, this material is tailored to support certification prep, board exams, and clinical rotations in addiction and mental health nursing. This resource is particularly useful for those affiliated with programs such as the University of Pennsylvania, Johns Hopkins University, UCLA School of Nursing, and members of the American Psychiatric Nurses Association (APNA) or other psychiatric nursing institutions. Keywords: CARN-AP, addictions nursing, substance use disorder, MAT, opioid use disorder, alcohol withdrawal, psychiatric nursing, DSM-5, clinical scenarios, naltrexone, disulfiram, benzodiazepines, nurse practitioner, PMHNP, FNP, NCLEX prep, advanced practice nursing, APNA, drug screening, Wernicke encephalopathy

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CARN-AP | ACTUAL EXAM 2025/2026
EXAM QUESTIONS AND ANSWERS |
100% PASS



One of the most common adverse effects seen in patients with ______

alcoholism is alcoholic neuropathy. - 🧠 ANSWER ✔✔chronic


Sensory symptoms often present _____ in alcoholic neuropathy. The first

clue may be _____ on the soles followed by dysesthesia on the feet. - 🧠

ANSWER ✔✔early


numbness

Activation of the sympathetic system by LSD causes:

- _______ blood pressure

- piloerection

- _____cardia

,- __________ body temperature


- pupillary _______ - 🧠 ANSWER ✔✔elevated


tachy

elevated

dilation

________- is known to cause vivid hallucinations with bright colors and

geometric objects. - 🧠 ANSWER ✔✔LSD


Flashbacks are associated with ______ use - 🧠 ANSWER ✔✔LSD


A 25-year-old female is being admitted to a residential treatment facility for

alcohol use disorder. Her last drink was 12 hours ago. On admission,

medication reconciliation is performed and it is discovered she is taking

bupropion for smoking cessation, sertraline for depression, and ibuprofen

as needed for headaches. Which of the following is the most appropriate

recommendation regarding the patient's medications at this time? - 🧠

ANSWER ✔✔Discontinue bupropion only.


Bupropion can only be administered _____

,Injection of dissolved bupropion can result in ____ and death - 🧠 ANSWER

✔✔orally.


seizure


Bupropion should be used with caution in patients with: - 🧠 ANSWER ✔✔-

CVD

- HTN

- CAD

Cognitive-behavioral groups are useful for changing what? - 🧠 ANSWER

✔✔beliefs and perceptions


This questionnaire is an introspective self-report questionnaire claiming to

indicate psychological preferences in how people make decisions and

perceive the world around them. - 🧠 ANSWER ✔✔The Myers-Briggs Type

Indicator (MBTI) assessment

Routine urine screens do not detect

- ______ cannabinoids

- _______

- _______

COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED

, - chemical variants of ______


- _____ - 🧠 ANSWER ✔✔synthetic


MDMA

ecstasy

opioids

PCP

Positive drug screens in patients without clinical symptoms may reflect the

detection of ________ and previous use - 🧠 ANSWER ✔✔metabolites


What is the name of an acute neurological condition characterized by a

clinical triad of:

1. ophthalmoparesis with nystagmus

2. gait ataxia


3. confusion - 🧠 ANSWER ✔✔Wernicke encephalopathy (WE)


The areas of the brain most often affected by Wernicke Korsakoff

syndrome are where? - 🧠 ANSWER ✔✔1. thalamus


2. mammillary bodies
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