NU708 Alcohol Abuse Exam | Advanced Nursing Assessment & Substance Use Management
Alcohol is the _______ leading cause of preventable death in US - (ANSWER)3rd
What is "heavy" drinking - (ANSWER)4 or more drinks in 2 hrs for women; 5 or more drinks in 2 hrs for
men
DSM-5 Criteria for Alcohol Use Disorder - (ANSWER)Problematic pattern of alcohol use leading to
impairment or distress as manifested by 2 of the following in a 12 mth period: Craving to use, persistent
desire or unsuccessful attempts to cut down or control use, using larger amounts over longer period
than was intended, failure to fulfill obligations because of recurrent ETOH use, great deal of time spent
re: ETOH, continued use despite physical psychological social or interpersonal problems caused by
alcohol use, missing activities because of alcohol, tolerance, withdrawal
tolerance of alcohol - (ANSWER)a condition in which a person needs more of a drug to feel the original
effects of the drug
dependence on alcohol - (ANSWER)the condition that results when the brain develops a chemical need
for a drug and cannot function normally without it
DSM-5 classifications for alcohol use disorder - (ANSWER)Mild is 2-3 criteria net
Mod 4-5 Criteria met
Severe 6+ criteria met
Psychosocial risk factors for alcohol use disorder - (ANSWER)early life, trauma, or abuse, family, history
of alcoholism, parental psychopathy other than alcohol, negative affect, hyperactivity distress, poor
executive functioning, poor parenting deficits in emotional reactivity, conduct problems in young
children, parental or pure, substance, abuse, academic delinquency, male, gender and little parental
support.
Alcohol effects what part of the brain? - (ANSWER)cerebellum -
ventral tegmental area or VTA
Explain what happens in the VTA when alcohol is present - (ANSWER)normally dopamine cells in the VTA
are kept in checked by GABA neurons which act like breaks. When alcohol is present, it reduces the
effects of the Gabon neurons or breaks. With less breaking the dopamine cells, fire more and release
, NU708 Alcohol Abuse Exam | Advanced Nursing Assessment & Substance Use Management
more dopamine into other brain areas like the nucleus accumbens. The extra dopamine release makes
alcohol feel rewarding and pleasurable, which reinforces drinking behavior and contributes to addiction.
What opioid antagonists are used for Alcohol Use Disorder? - (ANSWER)Naltrexone (Vivitrol) &
Nalmefene (Revex)
GABA activated chloride channel activation medication for Alcohol use disorder? - (ANSWER)Topiramate
(Topamax)
This medication is superior to nalmefene, naltrexone and acamprosate on consumption outcomes but
it's safety profile is known to be poor - (ANSWER)Topiramate (Topamax)
What NMDA receptor/Ca+ channels - (ANSWER)Acamprosate (Campral)
What GABAb agonist is used for alcohol use disorder - (ANSWER)Baclofen
First line treatment of AUD - (ANSWER)Naltrexone and Acamprosate
Second line treatment of Alcohol Use Disorder - (ANSWER)Gabapentin, Topiramate, and Disulfiram
Non-pharmacological treatments for Alcohol Use Disorder - (ANSWER)CST - Communication skills
training
CBT - cognitive behavioral therapy
CET - Cue-elicited therapy
CAT - Chemical Aversion Therapy
What receptor does naltrexone work on? - (ANSWER)MU opiate receptors
Describe how naltrexone works in alcohol use disorder - (ANSWER)Now Trione block the MU opiate
receptors, which results in alcohol creating less of a reward reaction in the brain resulting in the patient
having less cravings for alcohol
Alcohol is the _______ leading cause of preventable death in US - (ANSWER)3rd
What is "heavy" drinking - (ANSWER)4 or more drinks in 2 hrs for women; 5 or more drinks in 2 hrs for
men
DSM-5 Criteria for Alcohol Use Disorder - (ANSWER)Problematic pattern of alcohol use leading to
impairment or distress as manifested by 2 of the following in a 12 mth period: Craving to use, persistent
desire or unsuccessful attempts to cut down or control use, using larger amounts over longer period
than was intended, failure to fulfill obligations because of recurrent ETOH use, great deal of time spent
re: ETOH, continued use despite physical psychological social or interpersonal problems caused by
alcohol use, missing activities because of alcohol, tolerance, withdrawal
tolerance of alcohol - (ANSWER)a condition in which a person needs more of a drug to feel the original
effects of the drug
dependence on alcohol - (ANSWER)the condition that results when the brain develops a chemical need
for a drug and cannot function normally without it
DSM-5 classifications for alcohol use disorder - (ANSWER)Mild is 2-3 criteria net
Mod 4-5 Criteria met
Severe 6+ criteria met
Psychosocial risk factors for alcohol use disorder - (ANSWER)early life, trauma, or abuse, family, history
of alcoholism, parental psychopathy other than alcohol, negative affect, hyperactivity distress, poor
executive functioning, poor parenting deficits in emotional reactivity, conduct problems in young
children, parental or pure, substance, abuse, academic delinquency, male, gender and little parental
support.
Alcohol effects what part of the brain? - (ANSWER)cerebellum -
ventral tegmental area or VTA
Explain what happens in the VTA when alcohol is present - (ANSWER)normally dopamine cells in the VTA
are kept in checked by GABA neurons which act like breaks. When alcohol is present, it reduces the
effects of the Gabon neurons or breaks. With less breaking the dopamine cells, fire more and release
, NU708 Alcohol Abuse Exam | Advanced Nursing Assessment & Substance Use Management
more dopamine into other brain areas like the nucleus accumbens. The extra dopamine release makes
alcohol feel rewarding and pleasurable, which reinforces drinking behavior and contributes to addiction.
What opioid antagonists are used for Alcohol Use Disorder? - (ANSWER)Naltrexone (Vivitrol) &
Nalmefene (Revex)
GABA activated chloride channel activation medication for Alcohol use disorder? - (ANSWER)Topiramate
(Topamax)
This medication is superior to nalmefene, naltrexone and acamprosate on consumption outcomes but
it's safety profile is known to be poor - (ANSWER)Topiramate (Topamax)
What NMDA receptor/Ca+ channels - (ANSWER)Acamprosate (Campral)
What GABAb agonist is used for alcohol use disorder - (ANSWER)Baclofen
First line treatment of AUD - (ANSWER)Naltrexone and Acamprosate
Second line treatment of Alcohol Use Disorder - (ANSWER)Gabapentin, Topiramate, and Disulfiram
Non-pharmacological treatments for Alcohol Use Disorder - (ANSWER)CST - Communication skills
training
CBT - cognitive behavioral therapy
CET - Cue-elicited therapy
CAT - Chemical Aversion Therapy
What receptor does naltrexone work on? - (ANSWER)MU opiate receptors
Describe how naltrexone works in alcohol use disorder - (ANSWER)Now Trione block the MU opiate
receptors, which results in alcohol creating less of a reward reaction in the brain resulting in the patient
having less cravings for alcohol
